Metabolic Engineering of Yeast for the Production of 3-Hydroxypropionic Acid [PDF]
Frontiers in Microbiology, 2018 The beta-hydroxy acid 3-hydroxypropionic acid (3-HP) is an attractive platform compound that can be used as a precursor for many commercially interesting compounds.
Rong-Yu Ji +9 more
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Biocatalytic synthesis of 2-fluoro-3-hydroxypropionic acid [PDF]
Frontiers in Bioengineering and Biotechnology, 2022 Fluorine has become an important element for the design of synthetic molecules for use in medicine, agriculture, and materials. The introduction of fluorine atoms into organic compound molecules can often give these compounds new functions and make them ...
Wei Liu +4 more
doaj +4 more sources
Genome‐Scale Engineering Importing Property of Escherichia coli for Improving Production of 3‐Hydroxypropionic Acid [PDF]
Microbial BiotechnologyMicrobial biochemical production can suffer reduced growth and productivity from intracellular product accumulation, which can be mitigated by minimizing product import.
Seungjin Kim +4 more
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Enhanced 3-Hydroxypropionic Acid Production From Acetate via the Malonyl-CoA Pathway in Corynebacterium glutamicum [PDF]
Frontiers in Bioengineering and Biotechnology, 2022 Acetate is an economical and environmental-friendly alternative carbon source. Herein, the potential of harnessing Corynebacterium glutamicum as a host to produce 3-hydroxypropionic acid (3-HP) from acetate was explored.
Zhishuai Chang +8 more
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Engineering the synthetic β-alanine pathway in Komagataella phaffii for conversion of methanol into 3-hydroxypropionic acid. [PDF]
Microb Cell Fact, 2023 Background Methanol is increasingly gaining attraction as renewable carbon source to produce specialty and commodity chemicals, as it can be generated from renewable sources such as carbon dioxide (CO_2). In this context, native methylotrophs such as the
Àvila-Cabré S +3 more
europepmc +2 more sources
Benchmarking recombinant Pichia pastoris for 3‐hydroxypropionic acid production from glycerol [PDF]
Microbial Biotechnology, 2021 Summary The use of the methylotrophic yeast Pichia pastoris (Komagataella phaffi) to produce heterologous proteins has been largely reported. However, investigations addressing the potential of this yeast to produce bulk chemicals are still scarce.
Albert Fina +6 more
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Metabolic engineering to improve production of 3-hydroxypropionic acid from corn-stover hydrolysate in Aspergillus species. [PDF]
Biotechnol Biofuels Bioprod, 2023 Background Fuels and chemicals derived from non-fossil sources are needed to lessen human impacts on the environment while providing a healthy and growing economy.
Dai Z +14 more
europepmc +2 more sources
Engineering Glucose-to-Glycerol Pathway in Klebsiella pneumoniae and Boosting 3-Hydroxypropionic Acid Production Through CRISPR Interference [PDF]
Frontiers in Bioengineering and Biotechnology, 2022 The recent decline of the international biodiesel industry has led to decreased production and therefore increased the price of glycerol, which is a major by-product of biodiesel but a substrate for production of 3-hydroxypropionic acid (3-HP), that is ...
Hexin Liu, Peng Zhao, Pingfang Tian
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Adaptively evolved <i>Methylorubrum extorquens</i> with enhanced formate tolerance and its application in 3-hydroxypropionic acid production. [PDF]
Appl Environ MicrobiolMethylorubrum extorquens AM1, a native formate-utilizing bacterium, has exhibited limited capacity to tolerate formate. In this study, we employed an adaptive laboratory evolution (ALE) strategy to develop an evolved strain FT3 derived from M. extorquens
Mo X +7 more
europepmc +2 more sources
Construction and analysis of an artificial consortium based on the fast-growing cyanobacterium Synechococcus elongatus UTEX 2973 to produce the platform chemical 3-hydroxypropionic acid from CO2 [PDF]
Biotechnology for Biofuels, 2020 Background Cyanobacterial carbohydrates, such as sucrose, have been considered as potential renewable feedstock to support the production of fuels and chemicals.
Li Zhang +5 more
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