Results 21 to 30 of about 532 (88)

Hepatoprotective effect of kaempferol glycosides isolated from Cedrela odorata L. leaves in albino mice: involvement of Raf/MAPK pathway

Research in Pharmaceutical Sciences, 2021
Background and purpose: Paracetamol is the most implicated xenobiotic in inducing hepatotoxicity. Our study aimed to determine the impact of some kaempferol glycosides isolated from the leaves of Cedrela odorata L.
Gihan Farag Asaad, Heba Mohammed Ibrahim Abdallah, Hala Shaaban Mohammed, Yousra Ahmed Nomier   +3 more
doaj   +1 more source

Formation and biological role NO at an allergic inflammation

Бюллетень сибирской медицины, 2009
In the review ways and mechanisms of formation nitric oxide are considered. Effects metabolite nitric oxide in regulation of an allergic inflammation are analysed.
O. V. Kozina, L. M. Ogorodova
doaj   +1 more source

Relationship of Serum 3-Nitrotyrosine Levels with Inflammation in Patients with Rheumatoid Arthritis

Diagnostics
Objective: 3-Nitrotyrosine (3-NT) is a byproduct of tyrosine nitration, mediated by reactive nitrogen species such as peroxynitrite and nitrogen dioxide. It serves as a marker of cellular damage, inflammation, and nitric oxide activity.
Juan C. Quevedo-Abeledo, Fuensanta Gómez-Bernal, María García-González, Marta Hernández-Díaz, Cristina Almeida-Santiago, Pedro Abreu-González, Candelaria Martín-González, Miguel Á. González-Gay, Iván Ferraz-Amaro   +8 more
doaj   +1 more source

Exploring cardiovascular risk in subclinical hypothyroidism: The impact of TSHR gene expression and systemic biomarkers [PDF]

Journal of Cardiovascular and Thoracic Research
Introduction: Subclinical hypothyroidism (SCH), defined by elevated thyroid-stimulating hormone (TSH) with normal thyroid hormone levels, affects approximately 3–8% of the population.
Manjusha Kottola, Desigamani Kanniyappan, Damodaran Boopathi, Jeyapal Vidhyadharan, Vishnu Manjerikattil Govindan, Vineetha Vijayan, Joby Paruthiparayil Jose, Jisha Anjali Madhavan Pillai, Rajitha Puthiya Purayil, Swathi Thoduvayil, Midhun Thazhissery Mohanan, Dinesh Roy Divakaran   +11 more
doaj   +1 more source

How developmental stressors affect mitochondrial respiratory function: a systematic review and meta‐analysis

Biological Reviews, EarlyView.
ABSTRACT The environmental conditions organisms experience during early development can have powerful and sustained effects on morphology, physiology, behaviour, and performance. Such developmental effects can influence reproductive success, survival, and life‐history strategies and can be transmitted across generations (i.e.
Ondi L. Crino, Christopher R. Friesen, Geoffrey E. Hill, Dalton C. Leibold, Pablo Recio, Karine Salin, Kristoffer H. Wild, Daniel W.A. Noble   +7 more
wiley   +1 more source

Blood Levels of Glutamine and Nitrotyrosine in Patients with Chronic Viral Hepatitis

International Journal of General Medicine, 2021
Hussam Murad,1,2 Haythum Tayeb,3 Mahmoud Mosli,4 Misbahuddin Rafeeq,1 Mohammed Basheikh5 1Department of Pharmacology, Faculty of Medicine, Rabigh, King Abdulaziz University, Jeddah, Saudi Arabia; 2Department of Pharmacology, Faculty of Medicine, Ain ...
Murad H, Tayeb H, Mosli M, Rafeeq M, Basheikh M   +4 more
doaj  

Specific peptide enrichment strategies for neuropsychiatric disorders: From material design to diagnostic applications

Interdisciplinary Medicine, EarlyView.
This review outlines specific peptide enrichment strategies, including metal, magnetic oxides, functional polymers, and antibody‐based approaches, and their mechanisms, highlighting applications in biomarker discovery for major neurological and psychiatric disorders.
Xue Zhang, Yejiao Shi, Minghui Guo, Yang Huang, Yirong Wang, Leping Huang, Helena S. Azevedo, Honggang Hu, Xin Dong   +8 more
wiley   +1 more source

Simultaneous determination of 3-chlorotyrosine and 3-nitrotyrosine in human plasma by direct analysis in real time–tandem mass spectrometry

Acta Pharmaceutica Sinica B, 2015
A novel method for the simultaneous determination of 3-nitrotyrosine (NT) and 3-chlorotyrosine (CT) in human plasma has been developed based on direct analysis in real time–tandem mass spectrometry (DART–MS/MS).
Yuqiao Song, Jie Liao, Cheng Zha, Bin Wang, Charles C. Liu   +4 more
doaj   +1 more source

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source

Malondialdehyde and 3-Nitrotyrosine in Exhaled Breath Condensate in Retired Elderly Coal Miners with Chronic Obstructive Pulmonary Disease

Safety and Health at Work, 2014
Background: Chronic obstructive pulmonary disease (COPD) is an important cause of occupational mortality in miners exposed to coal mine dust. Although the inflammatory mediators involved in COPD have not been defined, many studies have shown that ...
Jong Seong Lee, Jae Hoon Shin, Ju-Hwan Hwang, Jin Ee Baek, Byung-Soon Choi   +4 more
doaj   +1 more source