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Cells, 2020 Much interest has been directed towards stem cells, both in basic and translational research, to understand basic stem cell biology and to develop new therapies for many disorders.
Joni H. Ylostalo
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Novel 3D-Printed Cell Culture Inserts for Air–Liquid Interface Cell Culture
Life, 2022 In skin research, widely used in vitro 2D monolayer models do not sufficiently mimic physiological properties. To replace, reduce, and refine animal experimentation in the spirit of ‘3Rs’, new approaches such as 3D skin equivalents (SE) are needed to ...
Magdalena Bauer +5 more
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Design approaches for 3D cell culture and 3D bioprinting platforms. [PDF]
Biophys Rev (Melville)The natural habitat of most cells consists of complex and disordered 3D microenvironments with spatiotemporally dynamic material properties. However, prevalent methods of in vitro culture study cells under poorly biomimetic 2D confinement or homogeneous conditions that often neglect critical topographical cues and mechanical stimuli. It has also become
Sreepadmanabh M +2 more
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3D cell culture - Methods and protocols
European Journal of Histochemistry, 2011 3D cell culture - Methods and ...
Carlo Alberto Redi
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Establishment of patient-derived three-dimensional organoid culture in renal cell carcinoma [PDF]
Investigative and Clinical Urology, 2020 Purpose: Renal cell carcinoma is a heterogeneous kidney cancer, and over 403,000 cases were reported worldwide in 2018. Current methods for studying renal cell carcinoma are limited to two-dimensional (2D) culture of primary cell lines and patient ...
Joon Chae Na +9 more
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European Journal of Cell Biology, 2022 Mesenchymal stem cells (MSCs) show a decline in pluripotency and differentiation with increased cell culture passages in 2D cultures. The 2D monolayer culture fails to correctly imitate the architecture and microenvironments of in-vivo cell models ...
Gitika Thakur +10 more
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3D Cell Culture—Can It Be As Popular as 2D Cell Culture?
Advanced NanoBiomed Research, 2021 A 3D cell culture has developed rapidly in recent years, as cells growing on a flat substrate in a static environment are far from achieving an in vivo status. Currently, researchers have also gradually realized that to achieve cell morphology, structure,
Miao Sun +7 more
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Pharmaceuticals, 2022 Despite tremendous advancements in technologies and resources, drug discovery still remains a tedious and expensive process. Though most cells are cultured using 2D monolayer cultures, due to lack of specificity, biochemical incompatibility, and cell-to ...
Shaimaa M. Badr-Eldin +4 more
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Bioactive Materials, 2023 Three-dimensional (3D) stem cell culture systems have attracted considerable attention as a way to better mimic the complex interactions between individual cells and the extracellular matrix (ECM) that occur in vivo.
Woochan Kim +4 more
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Biosensors, 2022 Cell culture plays an essential role in tissue engineering and high-throughput drug screening. Compared with two-dimensional (2D) in vitro culture, three-dimensional (3D) in vitro culture can mimic cells in vivo more accurately, including complex ...
Chunyang Wei +5 more
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