Results 11 to 20 of about 916,340 (306)

In Vitro three-dimensional (3D) cell culture tools for spheroid and organoid models

SLAS Discovery, 2023
Three-dimensional (3D) cell culture technology has been steadily studied since the 1990′s due to its superior biocompatibility compared to the conventional two-dimensional (2D) cell culture technology, and has recently developed into an organoid culture ...
Sang-Yun Lee, In-Seong Koo, Hyun Ju Hwang, Dong Woo Lee   +3 more
doaj   +1 more source

Is It Time to Start Transitioning From 2D to 3D Cell Culture?

Frontiers in Molecular Biosciences, 2020
Cell culture is an important and necessary process in drug discovery, cancer research, as well as stem cell study. Most cells are currently cultured using two-dimensional (2D) methods but new and improved methods that implement three-dimensional (3D ...
Caleb Jensen, Caleb Jensen, Yong Teng, Yong Teng, Yong Teng, Yong Teng   +5 more
doaj   +1 more source

Different Expression of Thyroid-Specific Proteins in Thyroid Cancer Cells between 2-Dimensional (2D) and 3-Dimensional (3D) Culture Environment

Cells, 2022
The two-dimensional (2D) monolayer culture as a conventional method has been widely applied in molecular biology fields, but it has limited capability to recapitulate real cell environments, being prone to misinterpretation with poor prediction of in ...
Ji Min Oh, Prakash Gangadaran, Ramya Lakshmi Rajendran, Chae Moon Hong, Jaetae Lee, Byeong-Cheol Ahn   +5 more
doaj   +1 more source

Development of Tissue Engineering Scaffolds for Cancer Cell Cultures [PDF]

Journal of Mazandaran University of Medical Sciences, 2023
The cell culture technique is one of the tools used in cellular and molecular biology such as cancer cell culture, regenerative medicine, and drug discovery.
Seyede Maryam Valizadeh Otaghsara, Hassan Dariushnejad, Amir Mellati, Elham Hasanzadeh, Mozhgan Abasi, Pedram Ebrahimnejad   +5 more
doaj  

3D Cell Culture in Alginate Hydrogels [PDF]

Microarrays, 2015
This review compiles information regarding the use of alginate, and in particular alginate hydrogels, in culturing cells in 3D. Knowledge of alginate chemical structure and functionality are shown to be important parameters in design of alginate-based matrices for cell culture. Gel elasticity as well as hydrogel stability can be impacted by the type of
Andersen, Therese, Auk-Emblem, Pia, Dornish, Michael   +2 more
openaire   +2 more sources

Microenvironment-Cell Nucleus Relationship in the Context of Oxidative Stress

Frontiers in Cell and Developmental Biology, 2018
The microenvironment is a source of reactive oxygen species (ROS) that influence cell phenotype and tissue homeostasis. The impact of ROS on redox pathways as well as directly on epigenetic mechanisms and the DNA illustrate communication with the cell ...
Shirisha Chittiboyina, Shirisha Chittiboyina, Yunfeng Bai, Sophie A. Lelièvre, Sophie A. Lelièvre, Sophie A. Lelièvre   +5 more
doaj   +1 more source

Expression of Tumor Assosiated and Epithelial-mesenchymal Transition Markers in 2d and 3d Cell Cultures of Mcf-7 [PDF]

, 2016
The target effects on the expression of epithelial-mesenchymal transition regulation molecules are promising for cancer therapy, including breast cancer.
Herheliuk, T. (Tetiana), Ostapchenko, L. (Lyudmila), Perepelytsina, O. (Olena), Sydorenko, M. (Mykhailo), Yurchenko, N. (Natalia)   +4 more
core   +2 more sources

Thiol-gelatin-norbornene bioink for laser‐based high‐definition bioprinting [PDF]

, 2020
Two-photon polymerization (2PP) is a lithography-based 3D printing method allowing the fabrication of 3D structures with sub-micrometer resolution.
Andriotis, Orestis G, Baudis, Stefan, Dobos, Agnes, Dubruel, Peter, Gruber, Peter, Markovic, Marica, Ovsianikov, Aleksandr, Rohatschek, Andreas, Steiger, Wolfgang, Thurner, Philipp J, Van Hoorick, Jasper, Van Vlierberghe, Sandra   +11 more
core   +1 more source

Multiplex Profiling of Cellular Invasion in 3D Cell Culture Models. [PDF]

, 2012
To-date, most invasion or migration assays use a modified Boyden chamber-like design to assess migration as single-cell or scratch assays on coated or uncoated planar plastic surfaces.
Burgstaller, Gerald, Eickelberg, Oliver, Koch, Ina, Lindner, Michael, Oehrle, Bettina   +4 more
core   +7 more sources

A miniaturized bioreactor system for the evaluation of cell interaction with designed substrates in perfusion culture [PDF]

, 2012
In tissue engineering, the chemical and topographical cues within three-dimensional (3D) scaffolds are normally tested using static cell cultures but applied directly to tissue cultures in perfusion bioreactors.
Anderson, Britland, Casey, Chen, Clark, Csaderova, Curtis, Curtis, Flemming, Gadegaard, Gadegaard, Gailit, Hubbell, Jelinek, Korin, Lakatos, Link, Lu, Massia, Mirastschijski, Mosmann, Noble, Robert, Salem, Seunarine, Stevens, Sun, Sun, Sørensen, Terai, Wojciak-Stothard, Zong   +31 more
core   +2 more sources