Results 101 to 110 of about 5,528,770 (310)

Les rencontres du Consortium 3D SHS Création -Usage scientifique - Conservation des données 3D

, 2020
La multiplication des initiatives autour de la création, des usages et de la conservation des données 3D dans les sciences humaines et sociales montrent une réelle nécessité de se coordonner afin de définir des standards dans les usages, les ...
Consortium 3D SHS Team
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Epigenetic and 3D genome reprogramming during the aging of human hippocampus

bioRxiv
Age-related cognitive decline is associated with altered physiology of the hippocampus. While changes in gene expression have been observed in aging brain, the regulatory mechanisms underlying these changes remain underexplored.
Nathan R. Zemke, Seoyeon Lee, Sainath Mamde, Bing Yang, Nicole C. Berchtold, B. Maximiliano Garduño, Hannah S. Indralingam, Weronika M. Bartosik, P. Lau, Keyi Dong, A. Yang, Yasmine Tani, Chu-Mo Chen, Qiurui Zeng, Varun Ajith, Liqi Tong, Chanrung Seng, Dao-Feng Li, Ting Wang, Xiangmin Xu, Bing Ren   +20 more
semanticscholar   +1 more source

aLTAG3D, un logiciel pour l'archivage 3D

, 2020
" aLTAG3D est un logiciel libre offrant une interface utilisateur simple et efficace pour la génération d'archive à long terme de projets 3D. L'archive générée est immédiatement compatible avec les services du CINES
Consortium 3D SHS Team
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[Video] Scientists turn to 3D technology to help restore Notre Dame

, 2021
"Scientists have enlisted the help of 3D imaging technology to restore Notre Dame to its former glory. A digital team from France's National Centre for Scientific Research has been working on the site for the past two years since the cathedral was ...
Consortium 3D SHS Team
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Demystifying cancer etiology via 3D genome mapping [PDF]

, 2020
Ramanand et al. perform the first high-resolution 3D genome mapping via ChIA-PET to capture RNAPII-associated chromatin interactions in normal prostate epithelial and prostate cancer cells.

core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

ARGV: 3D genome structure exploration using augmented reality

BMC Bioinformatics
Over the past two decades, scientists have increasingly realized the importance of the three-dimensional (3D) genome organization in regulating cellular activity.
Chrisostomos Drogaris, Yanlin Zhang, Eric Zhang, Elena Nazarova, Roman Sarrazin-Gendron, Sélik Wilhelm-Landry, Yan Cyr, Jacek Majewski, Mathieu Blanchette, Jérôme Waldispühl   +9 more
doaj   +1 more source

L’archivage pérenne des modèles numériques 3D pour les SHS

, 2020
Ce document est la formalisation d’une étape de la réflexion consacrée à l'archivage des données 3D mené au sein du consortium 3D SHS en collaboration avec Huma-Num et le CINES.
Consortium 3D SHS Team
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Developing a Toolset for 3D Genome Visualisation and Analysis

, 2022
In recent years 3D models of the genome emerges from Hi-C analysis and Imaging methods. To gain a better understanding of long distance relationships in DNA the analysis of the 3D structure of the genome is beginning.
Hofsøy, William
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