Results 141 to 150 of about 5,043,774 (177)

In vitro reconstitution of chromatin domains shows a role for nucleosome positioning in 3D genome organization. [PDF]

Nat Genet
Oberbeckmann E, Quililan K, Cramer P, Oudelaar AM.   +3 more
europepmc   +1 more source

ChIPr: accurate prediction of cohesin-mediated 3D genome organization from 2D chromatin features. [PDF]

Genome Biol
Abbas A, Chandratre K, Gao Y, Yuan J, Zhang MQ, Mani RS.   +5 more
europepmc   +1 more source

Human Body Single-Cell Atlas of 3D Genome Organization and DNA Methylation

Zhou J, Wu Y, Liu H, Tian W, Castanon RG, Bartlett A, Zhang Z, Yao G, Shi D, Clock B, Marcotte S, Nery JR, Liem M, Claffey N, Boggeman L, Barragan C, e Drigo RA, Weimer AK, Shi M, Cooper-Knock J, Zhang S, Snyder MP, Preissl S, Ren B, O’Connor C, Chen S, Luo C, Dixon JR, Ecker JR.   +28 more
europepmc   +1 more source

Understanding 3D Genome Organization by Multidisciplinary Methods [PDF]

Nature Reviews Molecular Cell Biology, 2021
Understanding how chromatin is folded in the nucleus is fundamental to understanding its function. Although 3D genome organization has been historically difficult to study owing to a lack of relevant methodologies, major technological breakthroughs in genome-wide mapping of chromatin contacts and advances in imaging technologies in the twenty-first ...
Ivana Jerković, Giacomo Cavalli
exaly   +3 more sources

Three-Dimensional Genome Organization in Immune Cell Fate and Function

Nature Reviews Immunology, 2023
Immune cell development and activation demand the precise and coordinated control of transcriptional programmes. Three-dimensional (3D) organization of the genome has emerged as an important regulator of chromatin state, transcriptional activity and cell
Ralph Stadhouders, Grégoire Stik, Sergi Cuartero   +2 more
exaly   +2 more sources

Some of the next articles are maybe not open access.

Related searches:

Organization and function of the 3D genome

Nature Reviews Genetics, 2016
Understanding how chromatin is organized within the nucleus and how this 3D architecture influences gene regulation, cell fate decisions and evolution are major questions in cell biology. Despite spectacular progress in this field, we still know remarkably little about the mechanisms underlying chromatin structure and how it can be established, reset ...
Bonev, B, Cavalli, Giacomo
openaire   +3 more sources

The Role of 3D Genome Organization in Development and Cell Differentiation

Nature Reviews Molecular Cell Biology, 2019
In eukaryotes, the genome does not exist as a linear molecule but instead is hierarchically packaged inside the nucleus. This complex genome organization includes multiscale structural units of chromosome territories, compartments, topologically associating domains, which are often demarcated by architectural proteins such as CTCF and cohesin, and ...
Hui Zheng, Wei Xie
exaly   +3 more sources

The 3D organization of the Mammalian Genome

The FASEB Journal, 2016
The 3D genome organization plays an essential role in orchestrating the many essential nuclear processes including gene regulation. Great strides have been made recently to characterize the 3D chromatin architecture in mammalian cells, with the development of both technologies for genome‐wide study of chromatin interactions at increasing precision and ...
openaire   +1 more source