Results 131 to 140 of about 43,182 (237)

The Eubacterium Rectale Derived Extracellular Vesicles Alleviate Cancer Cachexia Induced Lipolysis by Inhibiting Macrophage Polarization

Journal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
ABSTRACT Cancer cachexia (CC) is a complex pathological condition associated with cancer progression and poor prognosis, particularly in gastrointestinal cancers, and is closely linked to the gut microbiota. Lipolysis in CC may play a key role in driving cachexia progression.
Jiaqi Wang, Gulisudumu Maitiabula, Sirui Liu, Ruowen Li, Shijie Wang, Pinwen Zhou, Yufei Xia, Longchang Huang, Xin Chen, Xuejin Gao, Li Zhang, Xinying Wang   +11 more
wiley   +1 more source

Proteomic and Super‐Resolution Analyses of Murine Brown Adipocyte‐Derived Extracellular Vesicles

Journal of Extracellular Biology, Volume 5, Issue 5, May 2026.
Graphical Abstract ABSTRACT Thermogenic brown adipocytes (BAs) are not only an energy sink but also regulate systemic metabolic health through secreted factors and extracellular vesicles (EVs). Here, we investigate the baseline profiles BA‐EVs and how cold‐induced thermogenesis alters the proteome of BA‐EVs.
Menchus Quan, Yi‐Kai Liu, Maryam Mahmoodi, Muhammad Asif, Madeline Kay, Yongjie Yang, Fang Huang, Weiguo Andy Tao, Shihuan Kuang   +8 more
wiley   +1 more source

Isobavachromene ameliorates insulin resistance via inactivating the MAPK/NF-κB signaling pathway

Food Science and Human Wellness
Inflammation caused by obesity, particularly in adipose tissue and the liver, can lead to insulin resistance (IR) and trigger type 2 diabetes mellitus (T2DM). It is crucial to identify therapeutic agents that alleviate IR by reducing inflammation.
Zhenhua Liu, Zhenhua Liang, Lanting Xu, Jiajia Yuan, Yiqi Li, Wenyi Kang, Yan Zhang, Bin Cong   +7 more
doaj   +1 more source

Preliminary Evidence for Adipocytokine Signals in Skeletal Muscle Glucose Uptake

Frontiers in Endocrinology, 2018
The cross talk between the adipose tissue and insulin target tissues is a key mechanism for obesity-associated insulin resistance. However, the precise role of the interaction between the skeletal muscle and adipose tissue for insulin signaling and ...
Akihiro Kudoh, Hiroaki Satoh, Hiroyuki Hirai, Tsuyoshi Watanabe, Michio Shimabukuro   +4 more
doaj   +1 more source

The Evolving Therapeutic Landscape of Gallic Acid: A Review of Mechanistic Insights and Clinical Potential

Molecular Nutrition &Food Research, Volume 70, Issue 9, 13 May 2026.
ABSTRACT Gallic acid (GA), a plant‐derived phenolic compound, is evolving from a general antioxidant into a specific molecular modulator and a functional building block for advanced biomedical materials. This review synthesizes recent insights underpinned by GA's “redox duality”—its capacity to act as either a radical scavenger or a pro‐oxidant.
Woo Hyun Park
wiley   +1 more source

Grain–Oolong Tea Fermented Beverage Attenuates Adipogenesis-Related Phenotypes in 3T3-L1 Adipocytes

Fermentation
Obesity is a major global health concern, and functional fermented foods have attracted increasing attention for their potential metabolic benefits. Grain–oolong tea fermented beverage (GOFB), produced through a two-step spontaneous fermentation process,
Chih-Feng Wang, Chih-Chung Wu, Yi-Jou Chung, Cui-Rou Huang, Ying-Chen Lu   +4 more
doaj   +1 more source

Freely Available Tool (FAT) for automated quantification of lipid droplets in stained cells [PDF]

, 2017
In this study, wepropose an automatic procedure for digital image processing. Wedescribe a method that can efficiently quantify and characterizelipid droplets distributions in different cell types in culture.Prospectively, the lipid droplets detection ...
Bustos, Diego Martin, del Veliz, Samanta, Frontini López, Yesica Romina, Gojanovich, Aldana Daniela, Masone, Diego Fernando, Uhart, Marina   +5 more
core  

Effects of Phaseolus vulgaris Extract on Lipolytic Activity and Differentiation of 3T3-L1 Preadipocytes into Mature Adipocytes: A Strategy to Prevent Obesity

Journal of Nutrition and Metabolism, 2019
Background. Overweight and obesity are defined as abnormal or excessive fat accumulation that may be harmful for health. A global trend in this area is the search for natural compounds that have a proven beneficial effect and no clinical complications ...
Felipe Castillo, Daniel R. González, Rodrigo Moore-Carrasco   +2 more
doaj   +1 more source

The novel E3 ligase of PPAR?? TRIM25 regulates adipocyte differentiation [PDF]

, 2018
Department of Biological SciencesPeroxisome proliferator-activated receptor ?? (PPAR??) is a ligand-dependent transcription factor which regulates glucose homeostasis and adipocyte differentiation.
Lee, Jae Min
core  

Assessment of Adipocyte Transduction Using Different AAV Capsid Variants

Pharmaceuticals
Background/Objectives: Adeno-associated viruses (AAVs) are widely used as viral vectors for gene delivery in mammalian cells. We focused on the efficacy of the transduction of AAV2/5, 2/6, 2/8 and 2/9 expressing GFP in preadipocyte cells by live imaging ...
Stanislav Boychenko, Alina Abdullina, Viktor S. Laktyushkin, Andrew Brovin, Alexander D. Egorov   +4 more
doaj   +1 more source