Results 111 to 120 of about 259,851 (238)

Δ9 Tetrahydrocannabinol and cannabis extracts differentially improve adipoinsular dysfunction in diet‐induced obesity

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend THC and extract administered to diet‐induced obese mice reduced body weight and fat storage. Extract, but not THC, improved glucose clearance by a mechanism that may include restoring adipoinsular function. Abstract Diet‐induced obesity (DIO) is associated with dysregulated adipoinsular axis and endocannabinoid system (eCBS ...
Bryant Avalos   +7 more
wiley   +1 more source

Meroterpenoids Produced by Fungi: Occurrence, Structural Diversity, and Biological Activity (An Update: February 2020 to December 2025)

open access: yesChemistry &Biodiversity, Volume 23, Issue 11, November 2026.
This review firstly summarizes the update of meroterpenoids from February 2020 to December 2025 by applying a new classification method based on twelve key non‐terpene precursors. ABSTRACT Meroterpenoids are a class of hybrid natural products, biosynthesized from terpenoid fragments and non‐terpenoid precursors, exhibiting a wide range of biological ...
Yuqian Tang   +6 more
wiley   +1 more source

Phosphatidylcholine causes adipocyte-specific lipolysis and apoptosis in adipose and muscle tissues.

open access: yesPLoS ONE, 2019
Phosphatidylcholine (PPC) formula has been therapeutically used to reduce areas of localized fat. However, no single research has been carried out on its effect on a variety of cells in adipose and muscle tissues.
Tae Woo Jung   +11 more
doaj   +1 more source

Biological activities and bioactive constituents of Flammulina velutipes: An updated systematic review

open access: yesJournal of the Science of Food and Agriculture, Volume 106, Issue 14, Page 8298-8314, November 2026.
Abstract Flammulina velutipes (enokitake) is an edible mushroom recognized for both its nutritional and medicinal properties. It exhibits a broad spectrum of biological activities, including antioxidant, anti‐inflammatory, antitumor, immunomodulatory, and gut microbiota‐regulating effects.
Rıdvan Özgen   +2 more
wiley   +1 more source

Depot‐Specific Insulin Receptor Isoform Dynamics During Human Adipose‐Derived Stem Cell Adipogenesis

open access: yesObesity, Volume 34, Issue 11, Page 2124-2134, November 2026.
Absolute quantification reveals depot‐specific insulin receptor (IR) isoform signatures in human adipose stem cells, with subcutaneous cells enriched in IRa and exhibiting greater adipogenic capacity and insulin responsiveness. The emergence of IR‐negative adipocytes highlights partially receptor‐independent pathways regulating human adipogenesis ...
Valentina Annamaria Genchi   +10 more
wiley   +1 more source

Grain–Oolong Tea Fermented Beverage Attenuates Adipogenesis-Related Phenotypes in 3T3-L1 Adipocytes

open access: yesFermentation
Obesity is a major global health concern, and functional fermented foods have attracted increasing attention for their potential metabolic benefits. Grain–oolong tea fermented beverage (GOFB), produced through a two-step spontaneous fermentation process,
Chih-Feng Wang   +4 more
doaj   +1 more source

Representative immunoblots of NF-κB activation in 3T3-L1 preadipocytes and mature adipocytes.

open access: yes, 2014
3T3-L1 cells were treated with LPS (10 ng/ml); Palmitic acid (0.5 mM); Myristic acid (0.5 mM); and Oleic acid (0.5 mM) for 0, 1 and 2 h. Phosphorylation levels of p65 (Ser536) relative to total p65; and total levels of IκBα relative to α-tubulin were ...
Aimee L. Dordevic (575119)   +2 more
core   +1 more source

Adipocyte‐Derived Palmitic Acid Promotes Breast Cancer Malignancy via ZDHHC15‐Mediated S‐Palmitoylation of PPARγ

open access: yesCancer Science, Volume 117, Issue 11, Page 3007-3021, November 2026.
Adipocyte‐derived palmitic acid induces ZDHHC15‐mediated PPARγ S‐palmitoylation at Cys159, triggering its proteasomal degradation and promoting breast cancer malignancy with rosiglitazone resistance. Inhibition of PPARγ S‐palmitoylation by 2‐bromopalmitate suppresses breast cancer progression and synergistically enhances rosiglitazone efficacy ...
Geon Ho Moon   +6 more
wiley   +1 more source

Preliminary Evidence for Adipocytokine Signals in Skeletal Muscle Glucose Uptake

open access: yesFrontiers in Endocrinology, 2018
The cross talk between the adipose tissue and insulin target tissues is a key mechanism for obesity-associated insulin resistance. However, the precise role of the interaction between the skeletal muscle and adipose tissue for insulin signaling and ...
Akihiro Kudoh   +4 more
doaj   +1 more source

Representative immunoblots of MAPK phosphorylation in 3T3-L1 preadipocytes and mature adipocytes.

open access: yes, 2014
3T3-L1 cells were treated with LPS (10 ng/ml); Palmitic acid (0.5 mM); Myristic acid (0.5 mM); and Oleic acid (0.5 mM) for 0, 1 and 2 h. Phosphorylation levels of p38 (Thr180/Tyr182) relative to total p38; and phosphor-JNK (Thr183/Tyr185) relative to ...
Aimee L. Dordevic (575119)   +2 more
core   +1 more source

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