Strategies for Selecting Reliable Reference-Gene Combinations Across 2D and 3D Cell Culture Models. [PDF]
Life (Basel)Grigorova N.
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Shikonin: From Biosynthesis and Pharmacological Mechanisms to Translational Safety and Drug Delivery
ChemBioChem, Volume 27, Issue 21, 12 November 2026.Shikonin, biosynthesised in Boraginaceae roots from phenylalanine‐derived PHB and isoprenoid GPP, modulates redox balance, cellular stress, signalling pathways, and regulated cell death. Preclinical studies support diverse pharmacological activities, while nanocarriers improve dispersion and delivery.
Namini Joshi +6 more
wiley +1 more source
A diarylheptanoid from <i>Alpinia officinarum</i> ameliorates insulin resistance in 3T3-L1 adipocytes and db/db mice through modulation of PPARγ/PI3K/AKT signaling pathway. [PDF]
Front PharmacolChen Q +9 more
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Advanced Healthcare Materials, Volume 15, Issue 41, 6 November 2026.Recent advances in microfluidic technologies for microgel fabrication are critically reviewed, highlighting the capabilities and limitations of major microfluidic platforms and discussing how platform design, material selection, and crosslinking strategies influence microgel architecture and functionality. Current challenges and future opportunities in
Afshin Abrishamkar +6 more
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Transient activation of ciliary CCR2 signaling promotes the initiation of adipogenesis. [PDF]
Nat CommunWu Y +6 more
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Advanced Materials for Biologics Delivery to Brain Tumors
Advanced Materials, Volume 38, Issue 61, 2 November 2026.Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng +4 more
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Advanced Materials Interfaces, Volume 13, Issue 21, 6 November 2026.Strongly adhered cells align with concentric circular ridges and exhibit predominantly tangential motion, whereas weakly adhered cells fail to follow topographical guidance and display enhanced radial inward motion. ABSTRACT Living cells establish long‐range orientational order through collective alignment, giving rise to topological defects whose ...
Prasoon Awasthi +4 more
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Optical‐Field Engineering and Instrumentation in Brillouin Microscopy
Advanced Photonics Research, Volume 7, Issue 11, November 2026.Brillouin microscopy provides label‐free mechanical contrast through gigahertz light–acoustic interactions. This Review examines how optical‐field engineering and instrument architecture shape spectral precision, acquisition throughput, background rejection, spatial performance, and optical exposure.
Kangwen Tong +5 more
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Silver nanoparticles induce stress-associated upregulation of VEGF and FGF in fibroblasts as a compensatory response. [PDF]
PeerJTepchalee P +4 more
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BOULE is Essential for the Dynamic Disassembly of Heat Shock Granules in Male Germ Cells
Advanced Science, Volume 13, Issue 61, 3 November 2026.BOULE orchestrates stress granule disassembly in germ cells via a two‐pronged mechanism: it promotes G3BP1 ubiquitination by upregulating TRIM27, generating a signal for VCP/FAF2 recruitment, and it maintains G3BP1 and FAF2 protein levels. BOULE deficiency disrupts disassembly complex formation, leading to impaired heat shock granule clearance ...
Xin Li +8 more
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