Results 91 to 100 of about 4,503 (108)

Relevance of 24S-hydroxycholesterol as a biomarker of optic neuropathies

, 2009
 Purpose: 24S-Hydroxycholesterol is formed by enzymatic oxidation of cholesterol via cholesterol-24S-hydroxylase (CYP46A1) activity in neurons, including retinal ganglion cells and neurons from the inner retina.
Brétillon, Lionel, Pasquis, Bruno, Martine, Lucy, Bjorkhem, Ingemar, Schnebelen, Coralie, Bron, Alain, Acar, Niyazi, Creuzot Garcher, Catherine, Fourgeux, Cynthia   +8 more
core   +1 more source

Candidate-gene-based study of CYP3A-related single-nucleotide polymorphisms using 4β-hydroxycholesterol/cholesterol ratio as biomarker in a Japanese cohort. [PDF]

Eur J Clin Pharmacol
Tanaka R, Suzuki Y, Koyama T, Sumimoto T, Oda A, Sato H, Ozaki E, Tatsuta R, Yamamoto Y, Nakatochi M, Momozawa Y, Ohno K, Takashima N, Matsuo K, Itoh H.   +14 more
europepmc   +1 more source

Sterol Metabolism in Ovariectomized Rats: Potential Roles of Campesterol and 4β-Hydroxycholesterol in Osteoporosis. [PDF]

Lipids
He W, Eguchi S, Wang S, Tanaka Y, Sato M.   +4 more
europepmc   +1 more source

Was 4β-hydroxycholesterol ever going to be a useful marker of CYP3A4 activity? [PDF]

Br J Clin Pharmacol, 2018
Neuhoff S, Tucker GT.
europepmc   +1 more source

Modeling and simulation of the endogenous CYP3A induction marker 4β-hydroxycholesterol during enasidenib treatment. [PDF]

Clin Pharmacol, 2019
Li Y, Connarn JN, Chen J, Tong Z, Palmisano M, Zhou S.   +5 more
europepmc   +1 more source

Unusual oxidative pattern in thermo-oxidation of dry films of cholesterol

, 2017
Se estudió la formación de productos de oxidación del colesterol (POCs) durante calentamiento de una película seca de colesterol a 150°C. ha metodología empleada fue extracción en fase sólida (SPE), seguida por análisis en GC–MS para la identificación y ...
García, H.S., Rodríguez Estrada, M.T., Lercker, G., Soto Rodríguez, I., Medina Meza, I.G.   +4 more
core  

Kuypers and Vanhove reply to 'Was 4β-hydroxycholesterol ever going to be a useful marker of CYP3A4 activity?' by Neuhoff and Tucker. [PDF]

Br J Clin Pharmacol, 2018
Kuypers DRJ, Vanhove T.
europepmc   +1 more source

Gjestad et al. reply to 'Was 4β-hydroxycholesterol ever going to be a useful marker of CYP3A4 activity?' by Neuhoff and Tucker. [PDF]

Br J Clin Pharmacol, 2018
Gjestad C, Haslemo T, Andreassen OA, Molden E.   +3 more
europepmc   +1 more source

4β-Hydroxycholesterol level significantly correlates with steady-state serum concentration of the CYP3A4 substrate quetiapine in psychiatric patients. [PDF]

Br J Clin Pharmacol, 2017
Gjestad C, Haslemo T, Andreassen OA, Molden E.   +3 more
europepmc   +1 more source

4β-Hydroxycholesterol Level in Patients With Rheumatoid Arthritis Before vs. After Initiation of bDMARDs and Correlation With Inflammatory State. [PDF]

Clin Transl Sci, 2017
Wollmann BM, Syversen SW, Lie E, Gjestad C, Mehus LL, Olsen IC, Molden E.   +6 more
europepmc   +1 more source