Results 71 to 80 of about 477 (84)

4β-Hydroxycholesterol Level in Patients With Rheumatoid Arthritis Before vs. After Initiation of bDMARDs and Correlation With Inflammatory State. [PDF]

Clin Transl Sci, 2017
Wollmann BM, Syversen SW, Lie E, Gjestad C, Mehus LL, Olsen IC, Molden E.   +6 more
europepmc   +1 more source

4β-hydroxycholesterol correlates with dose but not steady-state concentration of carbamazepine: indication of intestinal CYP3A in biomarker formation? [PDF]

Br J Clin Pharmacol, 2016
Gjestad C, Huynh DK, Haslemo T, Molden E.   +3 more
europepmc   +1 more source

Differences in the Serum 4β-hydroxycholesterol Levels of Patients with Chronic Hepatitis C Virus (HCV) Infection: A Possible Impact on the Efficacy and Safety of Interferon (IFN)-free Treatment. [PDF]

Intern Med, 2018
Hirayama T, Ikegami T, Honda A, Miyazaki T, Yara SI, Kohjima M, Nakamuta M, Matsuzaki Y.   +7 more
europepmc   +1 more source

Validation of 4β-hydroxycholesterol and evaluation of other endogenous biomarkers for the assessment of CYP3A activity in healthy subjects. [PDF]

Br J Clin Pharmacol, 2014
Kasichayanula S, Boulton DW, Luo WL, Rodrigues AD, Yang Z, Goodenough A, Lee M, Jemal M, LaCreta F.   +8 more
europepmc   +1 more source

27-Hydroxycholesterol in bile duct tissue promotes cholangiocarcinoma progression through estrogen receptor signaling. [PDF]

Am J Cancer Res
Konishi N, Miyazaki T, Shimoda M, Morishita Y, Honda A, Ikegami T, Suzuki S.   +6 more
europepmc   +1 more source

A comparison of 4β-hydroxycholesterol : cholesterol and 6β-hydroxycortisol : cortisol as markers of CYP3A4 induction. [PDF]

Br J Clin Pharmacol, 2013
Mårde Arrhén Y, Nylén H, Lövgren-Sandblom A, Kanebratt KP, Wide K, Diczfalusy U.   +5 more
europepmc   +1 more source

Evaluation of 4β-Hydroxycholesterol as a Clinical Biomarker of CYP3A4 Drug Interactions Using a Bayesian Mechanism-Based Pharmacometric Model. [PDF]

CPT Pharmacometrics Syst Pharmacol, 2014
Leil TA, Kasichayanula S, Boulton DW, LaCreta F.   +3 more
europepmc   +1 more source

4β-Hydroxycholesterol, an endogenous marker of CYP3A4/5 activity in humans. [PDF]

Br J Clin Pharmacol, 2011
Diczfalusy U, Nylén H, Elander P, Bertilsson L.   +3 more
europepmc   +1 more source

The Disruption of <i>Cyp7b1</i> Controls IGFBP2 and Prediabetes Exerted Through Different Hydroxycholesterol Metabolites. [PDF]

Int J Mol Sci
Martínez-Beamonte R, Guillén N, Sánchez-Marco J, Herrera-Marcos LV, Surra JC, Navarro MA, Barranquero C, Arnal C, Puente JJ, Rodríguez-Yoldi MJ, Mendiara I, Domeño C, Nerín C, Geurts AM, Osada J, Laclaustra M.   +15 more
europepmc   +1 more source

Drug Interaction PBPK Modeling: Review of the Literature Exposes the Need for Increased Verification of Model Inputs and Outputs as Part of Credibility Assessment. [PDF]

Clin Transl Sci
Rodrigues D, Gibson CR, Isoherranen N.
europepmc   +1 more source