Results 111 to 120 of about 3,746 (131)

Deconvoluting Gut Versus Liver Cytochrome P450 3A4 Function: Drug Probes, Biomarkers, and Tissue Biopsy. [PDF]

J Clin Pharmacol
Rodrigues D.
europepmc   +1 more source

25-Hydroxycholesterol Effect on Membrane Structure and Mechanical Properties [PDF]

International Journal of Molecular Sciences, 2021
Cholesterol is responsible for the plasticity of plasma membranes and is involved in physiological and pathophysiological responses. Cholesterol homeostasis is regulated by oxysterols, such as 25-hydroxycholesterol.
Marco M Domingues, Barbara Gomes, Axel Hollmann   +2 more
exaly   +2 more sources

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Attenuation of 7-ketocholesterol- and 7β-hydroxycholesterol-induced oxiapoptophagy by nutrients, synthetic molecules and oils: Potential for the prevention of age-related diseases

Ageing Research Reviews, 2021
J P Pais de Barros, M Hammami, John J Mackrill   +2 more
exaly  

The cholesterol metabolite 25-hydroxycholesterol restrains the transcriptional regulator SREBP2 and limits intestinal IgA plasma cell differentiation

Immunity, 2021
Bruno C Trindade, Simona Ceglia, Alyssa Berthelette   +2 more
exaly  

The cholesterol metabolite 27-hydroxycholesterol inhibits SARS-CoV-2 and is markedly decreased in COVID-19 patients

Redox Biology, 2020
Alessandro Marcello, Rafaela Milan Bonotto, Lais Nascimento Alves   +2 more
exaly  

The Controversial Role of 24-S-Hydroxycholesterol in Alzheimer’s Disease

Antioxidants, 2021
Paola Gamba, Serena Giannelli, Erica Staurenghi   +2 more
exaly  

Crossing the barrier: net flux of 27-hydroxycholesterol into the human brain

Journal of Lipid Research, 2005
Steve Meaney, Dieter Lütjohann, Ulf Diczfalusy   +2 more
exaly  

4β‐Hydroxycholesterol as an endogenous marker for CYP3A4/5 activity. Stability and half‐life of elimination after induction with rifampicin

British Journal of Clinical Pharmacology, 2009
Ulf Diczfalusy, Kajsa P Kanebratt, Tommy B Andersson   +2 more
exaly  

Time course of the increase in 4β‐hydroxycholesterol concentration during carbamazepine treatment of paediatric patients with epilepsy

British Journal of Clinical Pharmacology, 2008
Leif Bertilsson, Ulf Diczfalusy
exaly  

Induction of oxiapoptophagy on 158N murine oligodendrocytes treated by 7-ketocholesterol-, 7β-hydroxycholesterol-, or 24(S)-hydroxycholesterol: Protective effects of α-tocopherol and docosahexaenoic acid (DHA; C22:6 n-3)

Steroids, 2015
Thomas Nury, Amira Zarrouk, John J Mackrill   +2 more
exaly