Results 91 to 100 of about 3,746 (131)

Was 4β-hydroxycholesterol ever going to be a useful marker of CYP3A4 activity? [PDF]

Br J Clin Pharmacol, 2018
Neuhoff S, Tucker GT.
europepmc   +1 more source

Modeling and simulation of the endogenous CYP3A induction marker 4β-hydroxycholesterol during enasidenib treatment. [PDF]

Clin Pharmacol, 2019
Li Y, Connarn JN, Chen J, Tong Z, Palmisano M, Zhou S.   +5 more
europepmc   +1 more source

CYP3A-fenotype, målt som 4β-hydroksykolesterol, hos pasienter før og etter nyretransplantasjon

, 2015
Bakgrunn: Cytokrom P450 3A (CYP3A)-enzymer er de viktigste enzymene i metabolisme av legemidler. Det er vist stor intra- og interdividuell variasjon i CYP3A-fenotype og 4β-hydroksykolesterol (4β-OH-K) er en aktuell endogen markør for denne variasjonen ...
Olastuen, Ane
core  

Kuypers and Vanhove reply to 'Was 4β-hydroxycholesterol ever going to be a useful marker of CYP3A4 activity?' by Neuhoff and Tucker. [PDF]

Br J Clin Pharmacol, 2018
Kuypers DRJ, Vanhove T.
europepmc   +1 more source

Gjestad et al. reply to 'Was 4β-hydroxycholesterol ever going to be a useful marker of CYP3A4 activity?' by Neuhoff and Tucker. [PDF]

Br J Clin Pharmacol, 2018
Gjestad C, Haslemo T, Andreassen OA, Molden E.   +3 more
europepmc   +1 more source

24-Hydroxycholesterol is a substrate for hepatic cholesterol 7 alpha-hydroxylase (CYP7A)

, 2000
(24S)-Hydroxycholesterol is formed from cholesterol in the brain and is important for cholesterol homeostasis in this organ. Elimination of (24S)-hydroxycholesterol has been suggested to occur in the liver but little is known about the metabolism of this
Toll, Anders,, Bjorkhem, Ingemar, Wikvall, Kjell,, Norlin, Maria,   +3 more
core  

4β-Hydroxycholesterol level significantly correlates with steady-state serum concentration of the CYP3A4 substrate quetiapine in psychiatric patients. [PDF]

Br J Clin Pharmacol, 2017
Gjestad C, Haslemo T, Andreassen OA, Molden E.   +3 more
europepmc   +1 more source

4β-Hydroxycholesterol Level in Patients With Rheumatoid Arthritis Before vs. After Initiation of bDMARDs and Correlation With Inflammatory State. [PDF]

Clin Transl Sci, 2017
Wollmann BM, Syversen SW, Lie E, Gjestad C, Mehus LL, Olsen IC, Molden E.   +6 more
europepmc   +1 more source

Differences in the Serum 4β-hydroxycholesterol Levels of Patients with Chronic Hepatitis C Virus (HCV) Infection: A Possible Impact on the Efficacy and Safety of Interferon (IFN)-free Treatment. [PDF]

Intern Med, 2018
Hirayama T, Ikegami T, Honda A, Miyazaki T, Yara SI, Kohjima M, Nakamuta M, Matsuzaki Y.   +7 more
europepmc   +1 more source

27-Hydroxycholesterol in bile duct tissue promotes cholangiocarcinoma progression through estrogen receptor signaling. [PDF]

Am J Cancer Res
Konishi N, Miyazaki T, Shimoda M, Morishita Y, Honda A, Ikegami T, Suzuki S.   +6 more
europepmc   +1 more source