Results 81 to 90 of about 3,746 (131)
Plasma levels of 24S-hydroxycholesterol in patients with neurological diseases
, 2000 The brain is the exclusive or almost exclusive site of formation of 24S-hydroxycholesterol and we have shown that the circulating level of 24S-hydroxycholesterol is dependent upon the relation between cerebral production and hepatic clearance.
Siden, A +9 more
core +1 more source
, 1995 The cytotoxicity of 25-hydroxycholesterol, 26-hydroxycholesterol and its analogue, 26-aminocholesterol was investigated in murine epidermal cell line, HEL-30.
R. Paoletti +4 more
core +1 more source
Missing Selectivity of Targeted 4β-Phorbol Prodrugs Expected to be Potential Chemotherapeutics
, 2019 Targeting cytotoxic 4β-phorbol esters toward cancer tissue was attempted by conjugating a 4β-pborbol derivative with substrates for the proteases prostate-specific antigen (PSA) and prostate-specific membrane antigen (PSMA) expressed in cancer tissue ...
Maria Helena Jäntti (8194386) +8 more
core +1 more source
, 1997 The first stereoselective synthesis of 2α,3α-epoxy-9β-benzoyloxy-β-agarofuran (3) and 2,3-dehydro-4β,12-epoxy-9β-benzoyloxy-β-dihydroagarofuran (4) from (-)-carvone in 13 steps, respectively, has been described.
Fajun Nan +5 more
core +1 more source
, 2007 The oxysterols 7 beta-hydroxycholesterol and 7-ketocholesterol are cholesterol autoxidation products. These two oxysterols are formed as a result of low density lipoprotein oxidation and in a study on biomarkers for oxidative stress in patients with ...
Diczfalusy U. +3 more
core +1 more source
, 1987 Oxidized derivatives of cholesterol, such as 26-hydroxycholesterol are an enzymatic oxidation product of cholesterol, which have been studied in vivo and in vitro systems.
Kou, I-Ling
core
, 2011 Formation of cholesterol oxidation products (COPs) during dry heating of cholesterol films at 150°C for 48 h was studied. A method based on aminopropyl solid-phase extraction (SPE), followed by GC-MS analysis was employed for the identification and ...
l. G. Medina Meza +4 more
core
Betydning av CYP3A4/5- og POR-genotype for individuell variasjon i nivå av 4β-hydroksykolesterol
, 2015 Problemstilling: Enzymer tilhørende cytokrom P450 3A (CYP3A)-subfamilen representerer de viktigste i metabolisme av legemidler. Det er stor individuell variasjon i CYP3A-fenotype, og 4β-hydroksykolesterol (4β-OH-K) er en aktuell biomarkør for denne ...
Heitmann, Kristine
core
Sterol Metabolism in Ovariectomized Rats: Potential Roles of Campesterol and 4β-Hydroxycholesterol in Osteoporosis. [PDF]
LipidsHe W +4 more
europepmc +1 more source
Relevance of 24S-hydroxycholesterol as a biomarker of optic neuropathies
, 2009 Purpose: 24S-Hydroxycholesterol is formed by enzymatic oxidation of cholesterol via cholesterol-24S-hydroxylase (CYP46A1) activity in neurons, including retinal ganglion cells and neurons from the inner retina.
Pasquis, Bruno +8 more
core