Results 101 to 110 of about 3,746 (131)

Validation of 4β-hydroxycholesterol and evaluation of other endogenous biomarkers for the assessment of CYP3A activity in healthy subjects. [PDF]

Br J Clin Pharmacol, 2014
Kasichayanula S, Boulton DW, Luo WL, Rodrigues AD, Yang Z, Goodenough A, Lee M, Jemal M, LaCreta F.   +8 more
europepmc   +1 more source

A comparison of 4β-hydroxycholesterol : cholesterol and 6β-hydroxycortisol : cortisol as markers of CYP3A4 induction. [PDF]

Br J Clin Pharmacol, 2013
Mårde Arrhén Y, Nylén H, Lövgren-Sandblom A, Kanebratt KP, Wide K, Diczfalusy U.   +5 more
europepmc   +1 more source

Evaluation of 4β-Hydroxycholesterol as a Clinical Biomarker of CYP3A4 Drug Interactions Using a Bayesian Mechanism-Based Pharmacometric Model. [PDF]

CPT Pharmacometrics Syst Pharmacol, 2014
Leil TA, Kasichayanula S, Boulton DW, LaCreta F.   +3 more
europepmc   +1 more source

4β-Hydroxycholesterol, an endogenous marker of CYP3A4/5 activity in humans. [PDF]

Br J Clin Pharmacol, 2011
Diczfalusy U, Nylén H, Elander P, Bertilsson L.   +3 more
europepmc   +1 more source

The Disruption of <i>Cyp7b1</i> Controls IGFBP2 and Prediabetes Exerted Through Different Hydroxycholesterol Metabolites. [PDF]

Int J Mol Sci
Martínez-Beamonte R, Guillén N, Sánchez-Marco J, Herrera-Marcos LV, Surra JC, Navarro MA, Barranquero C, Arnal C, Puente JJ, Rodríguez-Yoldi MJ, Mendiara I, Domeño C, Nerín C, Geurts AM, Osada J, Laclaustra M.   +15 more
europepmc   +1 more source

Plasma Biomarker Profiling of 2-Hydroxypropyl-β-Cyclodextrin (HPβCD) Treatment in an Aged Mouse Model of Ischemic Stroke. [PDF]

Int J Mol Sci
Becktel DA, Frye JB, Le EH, Schnellmann RG, Doyle KP.   +4 more
europepmc   +1 more source

Drug Interaction PBPK Modeling: Review of the Literature Exposes the Need for Increased Verification of Model Inputs and Outputs as Part of Credibility Assessment. [PDF]

Clin Transl Sci
Rodrigues D, Gibson CR, Isoherranen N.
europepmc   +1 more source

Impact of Efavirenz on Heme Protein Induction and Biomarkers: Insights From In Vitro Experiments and a Clinical Study. [PDF]

Clin Transl Sci
Potzel L, Kinzi J, Seibert I, Grube M, Siegmund W, Meyer Zu Schwabedissen HE.   +5 more
europepmc   +1 more source

<i>JAHA</i> Go Red for Women Spotlight 2026. [PDF]

J Am Heart Assoc
Peterson PN.
europepmc   +1 more source

Malignant hypertension and pseudohyperaldosteronism associated with rifampicin therapy. [PDF]

Cardiovasc Diabetol Endocrinol Rep
Szedleski A, Ilbert C, Goncette V, Vroonen L, Huart J.   +4 more
europepmc   +1 more source