Results 101 to 110 of about 4,522 (127)

Validation of 4β-hydroxycholesterol and evaluation of other endogenous biomarkers for the assessment of CYP3A activity in healthy subjects. [PDF]

Br J Clin Pharmacol, 2014
Kasichayanula S, Boulton DW, Luo WL, Rodrigues AD, Yang Z, Goodenough A, Lee M, Jemal M, LaCreta F.   +8 more
europepmc   +1 more source

A comparison of 4β-hydroxycholesterol : cholesterol and 6β-hydroxycortisol : cortisol as markers of CYP3A4 induction. [PDF]

Br J Clin Pharmacol, 2013
Mårde Arrhén Y, Nylén H, Lövgren-Sandblom A, Kanebratt KP, Wide K, Diczfalusy U.   +5 more
europepmc   +1 more source

Untargeted Metabolomics Reveal New Endogenous Plasma Biomarkers Associated with CYP3A Inhibition in Humans. [PDF]

Clin Pharmacol Ther
Yee SW, Kadar EP, Cerny MA, Vourvahis M, Tang LWT, Obach RS, Troutman MD, Varma MVS.   +7 more
europepmc   +1 more source

Evaluation of 4β-Hydroxycholesterol as a Clinical Biomarker of CYP3A4 Drug Interactions Using a Bayesian Mechanism-Based Pharmacometric Model. [PDF]

CPT Pharmacometrics Syst Pharmacol, 2014
Leil TA, Kasichayanula S, Boulton DW, LaCreta F.   +3 more
europepmc   +1 more source

4β-Hydroxycholesterol, an endogenous marker of CYP3A4/5 activity in humans. [PDF]

Br J Clin Pharmacol, 2011
Diczfalusy U, Nylén H, Elander P, Bertilsson L.   +3 more
europepmc   +1 more source

27-Hydroxycholesterol in bile duct tissue promotes cholangiocarcinoma progression through estrogen receptor signaling. [PDF]

Am J Cancer Res
Konishi N, Miyazaki T, Shimoda M, Morishita Y, Honda A, Ikegami T, Suzuki S.   +6 more
europepmc   +1 more source

The Disruption of <i>Cyp7b1</i> Controls IGFBP2 and Prediabetes Exerted Through Different Hydroxycholesterol Metabolites. [PDF]

Int J Mol Sci
Martínez-Beamonte R, Guillén N, Sánchez-Marco J, Herrera-Marcos LV, Surra JC, Navarro MA, Barranquero C, Arnal C, Puente JJ, Rodríguez-Yoldi MJ, Mendiara I, Domeño C, Nerín C, Geurts AM, Osada J, Laclaustra M.   +15 more
europepmc   +1 more source

25-Hydroxycholesterol Effect on Membrane Structure and Mechanical Properties [PDF]

International Journal of Molecular Sciences, 2021
Cholesterol is responsible for the plasticity of plasma membranes and is involved in physiological and pathophysiological responses. Cholesterol homeostasis is regulated by oxysterols, such as 25-hydroxycholesterol.
Nuno C. Santos, Axel Hollmann, Marco M Domingues   +2 more
exaly   +2 more sources

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Attenuation of 7-ketocholesterol- and 7β-hydroxycholesterol-induced oxiapoptophagy by nutrients, synthetic molecules and oils: Potential for the prevention of age-related diseases

Ageing Research Reviews, 2021
Pierre Andreoletti, John Mackrill, Atanas G. Atanasov   +2 more
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The cholesterol metabolite 27-hydroxycholesterol inhibits SARS-CoV-2 and is markedly decreased in COVID-19 patients

Redox Biology, 2020
Lais Nascimento Alves, Paolo Brambilla, David Lembo   +2 more
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