Results 121 to 130 of about 9,315,415 (239)
The crystal structures of two dihydropyridines were solved by direct methods and refined by full-matrix least-squares procedure. 2,6-Dimethyl-3,5-di[N-methyl]-carbamoyl-4-[3,4-methoxy]phenyl-1,4-dihydropyridine hemihydrate, C38H50N6O9 (compound 1 ...
core +1 more source
Abstract Heart failure with preserved ejection fraction (HFpEF) is associated with skeletal muscle dysfunction that contributes to exercise intolerance and disease progression. Altered Ca2+ homeostasis and increased oxidative stress have been proposed as mechanisms underlying muscle weakness in HFpEF; however, the effects of aerobic exercise on ...
Cielo Martínez Martínez +8 more
wiley +1 more source
Diethyl 4-(6-chloroimidazo[2,1-b]thiazol-5-yl)-2,6-dimethyl-1,4-dihydropyridine- 3,5-dicarboxylate and ethyl 4-(6-chloroimidazo[2,1-b]thiazol-5-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate were obtained simultaneously by the Biginelli ...
Mirella Rambaldi +9 more
core +1 more source
Recent Approaches for the Synthesis of Pyridine and Quinoline Cores Present in Natural Products
An anthology of the most recent methods used to synthesize pyridines and quinolines found in natural products over the last decade. Pyridines, quinolines, and their derivatives represent a class of significant heterocyclic compounds that are prevalent in a multitude of natural products, including alkaloids found in plants, fungi, insects, marine ...
Carl Bowman +2 more
wiley +1 more source
Application of a new high performance liquid chromatography method to the pharmacokinetics of dibudipine in rats [PDF]
Purpose: To develop a HPLC method for assay of dibudipine in biological fluids and to study its pharmacokinetics in the rat. Methods. HPLC: 2 μl (20 μg/ml) mebudipine as internal standard, 0.2 ml NaOH 1 M and 2 ml ethyl acetate were added to 0.2 ml of ...
محمودیان, مسعود +3 more
core
A New Synthetic Approach to the Preparation of Indolo[3,2‐c]quinolines From Sulfonylalkyl Indoles
Functionalized indolo[3,2‐c]quinolines can be efficiently prepared from sulfonylalkyl indoles by a cascade process involving reduction, vinylogous aza‐Michael and aromatization reactions triggered by zinc powder in acetic acid at reflux. The reductive cyclization of sulfonylalkyl indoles obtained from 2‐(o‐nitroaryl)indoles, provides an efficient ...
Francesca Cecchini +3 more
wiley +1 more source
Dimethyl 4-(3-hydroxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
The 1,4-dihydropyridine ring in the title compound, C17H19NO5, has a flattened-boat conformation, and the benzene ring is almost orthogonal to it [dihedral angle = 82.98 (12)°]. The hydroxy group is disordered over two positions in a 0.
V. Vijayakumar +9 more
core +1 more source
4H-Chromenyl-tetrahydro-2H-pyrancarboxylates 3a–k have been conveniently prepared by the reaction of 3-formylchromones 1a–k and ethyl 4,4,4-trifluoro-3-oxobutanoate 2a with good yields. Thus obtained 4H-chromenyl-tetrahydro-2H-pyrancarboxylates 3a–k were
Bhimapaka China Raju (736492) +3 more
core +1 more source
Propargilaizvietotāju saturošu 4-(N-alkilpiridil)-1,4-dihidropiridīna atvasinājumu iegūšana un īpašību pētījumi. Jēkabsone M. zinātniskais vadītājs doktorants, M.Sc. Ruciņš M.
Jēkabsone, Madara
core
Alzheimer’s disease is the most common cause of dementia in the elderly, and no disease-modifying therapy is yet available for this devastating pathology.
Srivastava, S. +7 more
core +1 more source

