Results 111 to 120 of about 19,839 (264)

The Brain‐Gut Axis in Parkinson's Disease Pathology

open access: yesComprehensive Physiology, Volume 16, Issue 2, April 2026.
Exposure to environmental toxins induces gut dysbiosis, increases intestinal epithelial barrier permeability, immune activation, and oxidative stress, promoting α‐syn misfolding and propagation. Brainstem DMV neurons exhibit α‐syn pathology, dysregulating neuronal excitability and vagal control of GI functions.
Kudret Selin Ozkaya   +1 more
wiley   +1 more source

Hydronium 4-oxo-1,4-dihydropyridine-3-sulfonate dihydrate

open access: yesActa Crystallographica Section E, 2009
2-Hydroxypyridine when treated with concentrated sulfuric acid is sulfonated at the 3-position to yield the title hydrated salt, H3O+·C5H4NO3S−·2H2O.
Zhi-Biao Zhu, Shan Gao, Seik Weng Ng
doaj   +1 more source

GREEN SYNTHESIS AND ANTIHYPERTENSIVE ACTIVITY OF SOME MANNICH BASES OF 1, 4 DIHYDROPYRIDINE COMPOUNDS

open access: yesInternational Journal of Biomedical Research, 2012
Some new Mannich Bases of 1, 4 Dihydropyridine derivatives were synthesised by reaction of 1, 4 Dihydropyridine derivatives formaldehyde (HCHO) & secondary amines (e.g. morpholine, 1-methyl piperazine) in 1:1 ratio under acidic condition in presence of trace HCl.
Pravin Jadhav   +2 more
openaire   +2 more sources

7-(3-Nitrophenyl)-9,10-dihydro-7H-benzo[h]cyclopenta[b]quinolin-8(11H)-one

open access: yesActa Crystallographica Section E, 2011
In the title compound, C22H16N2O3, the naphthalene ring, the 1,4-dihydropyridine ring and the cyclopent-2-enone ring are nearly coplanar, with the dihedral angles between the neighbouring rings being 1.93 (11) and 2.30 (9)&#176 ...
Tuanjie Li, Honghong Zhang
doaj   +1 more source

Evaluation of anticonvulsant activity of amlodipine in albino rats [PDF]

open access: yes, 2017
Background: The objective of the study was to evaluate the anticonvulsant activity of amlodipine in albino rats.Methods: Anticonvulsant activity of amlodipine was done in three graded doses (1 mg/kg, 2 mg/kg, 4 mg/kg), and combination group with low dose
B., Roopa   +2 more
core   +2 more sources

Kuwait Atrial Fibrillation Management Analysis—Insights From a Tertiary Center in Kuwait

open access: yesJournal of Arrhythmia, Volume 42, Issue 2, April 2026.
Among patients with non‐valvular AF, rhythm control (RC) was pursued in 28.9%. RC was pursued for younger patients and those followed in electrophysiology clinics (33% vs. 5%, p < 0.001). 11.6% of patients received an underdosed DOAC. RC was underutilized in our study, falling short of international benchmarks and guideline recommendations.
S. AlKharji   +3 more
wiley   +1 more source

Spectroscopic studies of hydrophobic association of merocyanine dyes in cationic and anionic micelles [PDF]

open access: yes, 1977
Merocyanine dyes exhibit interesting changes in absorption spectra with changes in solvent polarity. For example solutions of 1-methyl-4- (oxocyclohexadienylidene) ethylidene -1,4-dihydropyridine (MOED) are yellow, red, violet, or blue, in water, ethanol,
Shah, Sayed Sadiq
core   +1 more source

Síntesis y evaluación antioxidante para monocarbonil curcuminoides y sus derivados [PDF]

open access: yes, 2018
Introduction: Curcumin is a yellow pigment extracted from the Curcuma longa L, which have a several biological activities and pharmacological properties.
E, Abood, K N, Agel, T, Alsalim
core   +3 more sources

Predictors and Outcomes of Pharmacological and Electrical Cardioversion for Atrial Fibrillation and Flutter in an Indian Emergency Department: A Retrospective Study

open access: yesJournal of Arrhythmia, Volume 42, Issue 2, April 2026.
In a real‐world emergency department study of atrial fibrillation and flutter, cardioversion restored sinus rhythm in 68% of patients. Electrical cardioversion achieved the highest success, while pharmacological and mixed strategies predicted failure. Complications were infrequent but clinically significant.
Abid M. Sadiq   +3 more
wiley   +1 more source

Investigation of Novel Heterocyclic Compounds as Inhibitors of Al-3Mg Alloy Corrosion in Hydrochloric Acid Solutions

open access: yesInternational Journal of Electrochemical Science, 2012
The inhibition of Al-3Mg alloy corrosion in 0.5 M and 1 M HCl by newly prepared compounds namely: 4-(methoxymethyl)-1,6-dimethyl-2-oxo-1,2- dihydropyridine-3-carbonitrile (compound A) and 4-amino-3,5-bis [6-(methoxymethyl)-3,4-dimethyl-2-oxo-1,2 ...
Jasna Halambek   +3 more
doaj   +1 more source

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