Results 111 to 120 of about 90,592,261 (228)

Diethyl 4-(6-Chloroimidazo[2,1-b]thiazol-5-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate and Ethyl 4-(6-Chloroimidazo[2,1-b]thiazol-5-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

, 2012
Diethyl 4-(6-chloroimidazo[2,1-b]thiazol-5-yl)-2,6-dimethyl-1,4-dihydropyridine- 3,5-dicarboxylate and ethyl 4-(6-chloroimidazo[2,1-b]thiazol-5-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate were obtained simultaneously by the Biginelli ...
Mirella Rambaldi, LEONI, ALBERTO, Alessandra Locatelli, Rita Morigi, MORIGI, RITA, RAMBALDI, MIRELLA, Alberto Leoni, Alessandro Consorti, A. Consorti, LOCATELLI, ALESSANDRA   +9 more
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Synthesis and crystal structure of a novel substituted 1,4-dihydropyridine [PDF]

, 2007
The title compound, C15H16N2O3, was synthesized, characterized spectroscopically, and finally confirmed by X-ray diffraction studies. The compound crystallizes in the monoclinic space group P21/n with cell parameters a = 10.314(9) Å, b = 17.976(15) Å, c =
Naveen, S., Virsodia, Vijay, Shashidhara Prasad, J., Kakadiya, Rajesh, Bariwal, Jitender, Anandalwar, Sridhar M., Karia, Denish, Shah, Anamik   +7 more
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Diethyl 4-(2,4-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

, 2010
In the title compound, C19H21Cl2NO4, the dihydropyridine ring adopts a flattened boat conformation. The dichlorophenyl ring is oriented almost perpendicular to the planar part of the dihydropyridine ring [dihedral angle = 89.1 (1)&#176 ...
V. Vijayakumar, P. L. Nilantha Lakshman, P. Palakshi Reddy, J. Suresh, T. Narasimhamurthy   +4 more
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Dihydropyridine Isomerism in the Chemical Delivery System Series [PDF]

, 1993
A theoretical study was performed for three structured isomers of the dihydropyridine-targetor btised chemical delivery systems of estradiol euid azidothymine.
Bodor, Nicholas, Brewster, Marcus E., Huang, Ming-Ju, Pop, Emil   +3 more
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Multitarget Drug Design for Cardiovascular Disease: Bridging Chemistry and Medicine [PDF]

ChemMedChem
Many pathophysiological pathways associated with cardiovascular diseases involve multiple drug targets. This article reviews recent advances in the development of pharmacological compounds capable of simultaneously modulating multiple mechanisms. Multitarget drugs offer a promising therapeutic approach for complex cardiovascular disorders, including ...
Mitronova G, Belov V, Schmidt C, Lehnart S.   +3 more
europepmc   +2 more sources

A simple and convenient synthesis of tautomeric (6 or 2)-hydroxy-4-methyl-(2 or 6)-oxo-1-(substituted phenyl)-(1,2 or 1,6)-dihydropyridine-3-carbonitriles

, 2013
A simple and convenient synthesis of tautomeric (6 or 2)-hydroxy-4-methyl-(2 or 6)-oxo-1-(substituted phenyl)-(1,2 or 1,6)-dihydropyridine-3-carbonitriles from ethyl acetoacetate and 2-cyano-N-(substituted phenyl)ethanamides using microwave-assisted ...
Brković, Danijela, Veselin Maslak, Danijela Brkovic, Marinković, Aleksandar, Milos Milcic, Aleksandar Marinkovic, Brković, Danijela V, Ajaj, Ismail A., Mijin, Dušan, Maslak, Veselin, Todorović, Nina, Ajaj, Ismail, Marinković, Aleksandar D., Ismail Ajaj, Dusan Mijin, Milčić, Miloš K., Milčić, Miloš, Nina Todorovic   +17 more
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PartI. Study of 1-Acyl-2-dimethylphenylsilyl-2,3-dihydro-4-pyridone as Synthetic Intermediates. Part II. Synthesis of Nicotine Derivatives from Nicotine.

, 2005
Various methodologies were investigated to build synthetic intermediates from 1-acyl-2-dimethylphenylsilyl-2,3-dihydro-4-pyridones and to synthesize nicotine derivatives from nicotine.
Smith, Emilie Despagnet
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Bactericidal and immunomodulatory properties of magnetic nanoparticles functionalized by 1,4-dihydropyridines

International Journal of Nanomedicine, 2018
Katarzyna Niemirowicz-Laskowska,1 Katarzyna Głuszek,1 Ewelina Piktel,1 Karlis Pajuste,2 Bonita Durnaś,3 Grzegorz Król,3 Agnieszka Z Wilczewska,4 Paul A Janmey,5 Aiva Plotniece,2 Robert Bucki1 1Department of Microbiological and Nanobiomedical ...
Niemirowicz-Laskowska K, Głuszek K, Piktel E, Pajuste K, Durnaś B, Król G, Wilczewska AZ, Janmey PA, Plotniece A, Bucki R   +9 more
doaj  

Onset time of Ca antagonistic action of CD-349 in comparison with other dihydropyridine compounds

, 2007
AN0016561X-20071226-77We examined the relationship between the tissue distribution and the time of onset of the calcium antagonistic action of CD-349 in comparison with nicardipine and nitrendipine.
WATAJIMA, Hiroshi, 1450, 1591, ワタジマ, ヒロシ, 1590, TSUCHIDA, Katsuharu, ツチダ, カツハル, OGAWA, Naoyoshi, 520, 335, オガワ, ナオヨシ, 土田, 勝晴, 519   +12 more
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High-affinity antibodies to the 1,4-dihydropyridine Ca2+- channel blockers (nitrendipine/nifedipine/nisoldipIne/Ca2' antgonsts/dihydropyridlne receptor)

, 2020
Antibodies with affinity and specificity for the 1,4-dihydropyridine Ca2+-channel blockers have been produced in rabbits by immunization with dihydropyridine-protein conjugates. Drugs that block these voltage-dependent Ca2' channels are used for the
Alan Sharp, Kevin P Campbell, Steven D Kahl, AND Molly Strom   +3 more
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