Results 111 to 120 of about 9,315,415 (239)

Malignant Hyperthermia in Sweden: Clinical Presentations and Genetic Findings

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 6, July 2026.
ABSTRACT Introduction Malignant hyperthermia (MH) is a pharmacogenetic, hypermetabolic and potentially lethal reaction to potent volatile anaesthetics and the muscle relaxant succinylcholine. To improve the understanding of MH, the aim of this retrospective study was to describe the Swedish cohort with respect to clinical manifestations, demographics ...
Anna Hellblom, Maria Soller, Carolina Samuelsson   +2 more
wiley   +1 more source

7-(3-Nitrophenyl)-9,10-dihydro-7H-benzo[h]cyclopenta[b]quinolin-8(11H)-one

Acta Crystallographica Section E, 2011
In the title compound, C22H16N2O3, the naphthalene ring, the 1,4-dihydropyridine ring and the cyclopent-2-enone ring are nearly coplanar, with the dihedral angles between the neighbouring rings being 1.93 (11) and 2.30 (9)&#176 ...
Tuanjie Li, Honghong Zhang
doaj   +1 more source

Gallium(III) chloride as an efficient new catalyst for the production of Hantzsch 1 ,4-dihydropyridines

, 2009
Department of Chemistry, Punjabi University, Patiala-147 002, Punjab, india E-mail : j_sandhu2002@yahoo.com Manuscript received 16 March 2009, accepted 26 May 2009 Hantzsch 1,4-dihydropyridines (DHPs) are synthesized In good to excellent yields from aldehydes, 1,3-dicarbonyl compounds and ammonium acetate using gallium(lll) chloride which acts as ...
Dhruva Kumar, Saini, Anil, , Suresh, Sandhu, Jagir S.   +3 more
openaire   +1 more source

A Case Report of PR Interval Prolongation Caused by Amlodipine

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Amlodipine is a widely used dihydropyridine calcium channel blocker. Its effects on the cardiac conduction system, especially PR interval prolongation, are rare but clinically important. We report a 25‐year‐old healthy male subject in a clinical trial with baseline first‐degree atrioventricular block (PR interval 230 ms).
Zhiying Fu, Suping Ling, Xiaoli Ji, He Zhu   +3 more
wiley   +1 more source

Persistent Arrhythmogenic Effects of COVID‐19: A Comprehensive Analysis of Device Implantation and Antiarrhythmic Interventions in Japan

Journal of Arrhythmia, Volume 42, Issue 3, June 2026.
COVID‐19 was associated with a sustained increase in device implantation and arrhythmia‐related interventions over 2 years. In a nationwide propensity score‐matched cohort, risks of pacemaker, ICD, CRT implantation, ablation procedures, and antiarrhythmic medication initiation remained higher after COVID‐19, supporting long‐term cardiovascular ...
Daisuke Miyamori, Shuhei Yoshida, Masanori Ito   +2 more
wiley   +1 more source

Investigation of Novel Heterocyclic Compounds as Inhibitors of Al-3Mg Alloy Corrosion in Hydrochloric Acid Solutions

International Journal of Electrochemical Science, 2012
The inhibition of Al-3Mg alloy corrosion in 0.5 M and 1 M HCl by newly prepared compounds namely: 4-(methoxymethyl)-1,6-dimethyl-2-oxo-1,2- dihydropyridine-3-carbonitrile (compound A) and 4-amino-3,5-bis [6-(methoxymethyl)-3,4-dimethyl-2-oxo-1,2 ...
Jasna Halambek, Marijana Jukić, Katarina Berković, Jasna Vorkapić-Furač   +3 more
doaj   +1 more source

Comparative Effectiveness and Safety of Three Oral Antihypertensive Therapies on Maternal and Infant Outcomes in a California Medicaid Population, 2016–2020

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 6, June 2026.
ABSTRACT Purpose To extend the Chronic Hypertension and Pregnancy (CHAP) trial findings, this study compared labetalol, nifedipine, and methyldopa initiation at or before 23 weeks' gestation in pregnant patients with chronic hypertension, examining effects on a composite effectiveness outcome and on small for gestational age birth (SGA).
Catherine Psaras, Erin Delker, Rebecca J. Baer, Clare M. Cutri‐French, Gretchen Bandoli   +4 more
wiley   +1 more source

Antischistosomal Activity of 1,4-Dihydropyridines

Drugs and Drug Candidates
Background/Objectives: Recent reports have demonstrated the antiparasitic activity of 1,4-dihydropyridine (1,4-DHPs). This study aimed to assess the in vitro antischistosomal activity of 24 1,4-DHPs against Schistosoma mansoni adult worms.
Thaís A. S. Oliveira, Matheus H. M. Zago, Larissa G. Maciel, Yan R. Robles, Lizandra G. Magalhães, Antônio E. M. Crotti   +5 more
doaj   +1 more source

Role of novel automated methods in pulse signal analysis to screen for sleep‐disordered breathing among patients on chronotropic medications

Sleep Research, Volume 3, Issue 2, Page 98-107, June 2026.
Abstract Study objectives To investigate the use of automated analysis to detect heart rate accelerations (HRAs) to screen for sleep‐disordered breathing (SDB) among patients who use chronotropic medications. Methods Nocturnal polysomnography (NPSG) recordings from 933 participants in the Sleep Heart Health Study were analyzed using an automated method
Nabila Ahmed, Moustafa Habra, Raya Nashef, Scott Maresh, Abed Najjar, Shivapriya Chandu, Adhithi Athikumar, Omar Ismail, Laurel A. Ravelo, Paul E. Peppard, M. Safwan Badr, Abdulghani Sankari   +11 more
wiley   +1 more source

Fixed‐Dose Combinations for Hypertension: Barriers to Use and Opportunities for Health Systems

The Journal of Clinical Hypertension, Volume 28, Issue 6, June 2026.
ABSTRACT Background: Uncontrolled hypertension is a leading driver of heart disease, chronic kidney disease, heart failure, dementia, stroke, and pregnancy‐related complications. Fixed‐dose combinations (FDCs) are guideline‐endorsed first‐line therapies that improve blood pressure control by reducing pill burden, improving adherence, and targeting ...
Pranay Narang, Josselyne Marquez, Neema Rashidi, Rohini Haar, Sandeep P. Kishore   +4 more
wiley   +1 more source