Results 101 to 110 of about 19,839 (264)
Synthesis and Characterization of Novel (E)-1-(Aylideneamino)-6-(4-Methoxyphenyl)-2-Oxo-4-(Trifluoromethyl)-1,2-Dihydropyridine-3-Carbonitrile Derivatives [PDF]
Hasmukh R. Khunt +4 more
openalex +3 more sources
QSAR Modeling of COX-2 Inhibitory Activity of Thiazinan, Benzthiazinan and Benzdiazinan Derivatives [PDF]
COX-2 inhibitory activities of some thiazinan, benzdiazinan and benzthiazinan derivatives were modeled by quantitative structure–activity relationship (QSAR) with stepwise-multiple linear regression (SW-MLR) method.
Akbarpour Avini, Sara +3 more
core +2 more sources
A Case Report of Acute Renal Failure due to Amlodipine Overdose and Alcohol Consumption
ABSTRACT Amlodipine intoxication is clinically common yet life‐threatening, usually resulting in severe cardiovascular collapse and end‐organ hypoperfusion. Here, we report a case of a 46‐year‐old male with amlodipine (420 mg) and ethanol intoxication who unexpectedly presented without severe hypotension or shock.
Yi Xi
wiley +1 more source
As a follow-up to our previous studies on differently substituted 1,4-dihydropyridines endowed with a peculiar cardiac selectivity, in this paper, a small series of hybrid compounds bearing the pharmacophore fragment of lidoflazine in position 2 or 3 on ...
Alessandra Bisi +5 more
doaj +1 more source
Investigating the Anti-Cancer Properties of Novel Hybrid 1,4-Dihydropyridine Derivatives in U-87MG Glioblastoma Cell [PDF]
Glioblastoma is the most devastating of brain cancers with a very high death rate and a low survival rate of less than 15 months after diagnosis. Glioblastoma is a cancer of astrocytes which are the majority of the brain glial cells that support neurons ...
Hunyenyiwa, Tendai
core +1 more source
Organophotoredox/Cobalt‐Catalyzed Retro‐Hydroformylation of Aldehydes
A new photoredox/cobalt retro‐hydroformylation is developed. This one‐pot two‐step process involves the in situ formation of the corresponding 1,4‐dihydropyridine as key intermediate. Under mild reaction conditions, alkenes are efficiently produced from a wide range of aliphatic α‐monosubstituted aldehydes, with high functional‐group tolerance.
Augustin Nouaille +3 more
wiley +1 more source
Idhayadhulla Akbar,1 Surendrakumar Radhakrishnan,1 Karpakavalli Meenakshisundaram,2 Aseer Manilal,3 Ashraf Atef Hatamleh,4 Bassam Khalid Alnafisi,4 Anis Ahamed,4 Ravindran Balasubramani5 1Research Department of Chemistry, Nehru Memorial College ...
Akbar I +7 more
doaj
One-pot two-step Hantzsch synthesis of 4-(3,5-dibromo-4-hydroxyphenyl)-3- butoxycarbonyl-5-ethoxycarbonyl-2-methyl-6-phenyl-1,4-dihydropyridine under solvent- and catalyst-free conditions promoted with microwave irradiation is presented.
Zhen Wang, Qingjian Liu
doaj +1 more source

