Results 251 to 260 of about 19,839 (264)

Enantioselective analysis of 1, 4-dihydropyridine drugs by luquid chromatography

2004
The analyses for the following substances were performed: isradipine, nitrendipine, nicardipine, nisoldipine and felodipine. The most successful separations for the all investigated compounds were achieved on Chiralpak AD column that consist of amylose tris(3, 5-dimethylphenylcarbamat) as chiral selector.
Kalčić, Igor, Vinković, Vladimir, Litvić, Mladen   +2 more
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Enantioselective and diastereoselective preparation of 1, 4-dihydropyridines

2004
Ispitane su različite metode za pripravu enantiomerno čistih 1, 4-dihidropiridinskih spojeva (1, 4-DHP). Rezultati pokazuju da se ovaj tip spojeva dobiva vrlo teško u enantiomerno čistom obliku i da ne postoji jedna općenita metoda za njihovu pripravu.
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Exploring 1, 4-Dihydropyridines: Synthesis, Biological Activities, Therapeutic Potentials and Computational Studies

Abstract: 1, 4-dihydropyridines and their derivatives are the foremost notable class of Nitrogen-containing heterocyclic scaffolds and have been extensively used since they are occupying the highest position in the pharmaceutical industry because of its wider range of biological and medicinal uses.
Sodah, Karun, Khilnani, Dr. Veena, Sharma, Prerna   +2 more
openaire   +1 more source

Synthesis and Biological Evaluation of New 1, 4-Dihydropyridines as Antihypertensives Agents in Rats

2003
New analogues of nifedipine, as a known calcium channel blocker, were synthesized by replacing the orthonitrophenyl group on position 4 with 1-(4-Nitrobenzyl)-5-imidazolyl or 2methylthio-1-(4-Nitrobenzyl)-5-imidazolyl substituent. Effects of the new synthesized compounds on blood pressure were studied at 15, 30 and 60 min after administration by ...
Jorjani, M, Rastegar, H, Roshanzamir, F, Varmazyari, M, Abdollahi, M, Zarghi, Afshin   +5 more
openaire   +1 more source

Synthese de diacyl-1,4 alcoyl-4 dihydropyridines

Tetrahedron Letters, 1969
P.M. Atlani, J.F. Biellmann
openaire   +1 more source

Synthesis and pharmacological activity of 4-aryl-l,4-dihydropyridines

Pharmaceutical Chemistry Journal, 1982
V. V. Kastron, G. Ya. Dubur, R. O. Vitolin', A. A. Kimenis, M. Ya. Selga, N. V. Kondratenko, L. M. Yagupol'skii, D. Ya. Tirzite, Yu. A. Fialkov, S. V. Shelezhenko   +9 more
openaire   +1 more source

Rotational Barriers of 4‐Aryl‐1, 4‐dihydropyridines (Ca Antagonists)

Angewandte Chemie International Edition in English, 1984
Siegfried Goldmann, Walter Geiger
openaire   +1 more source

Catalytic Aromatization Of Hantzsch 1, 4 - Dihydropyridines With Tert-Butylhydroperoxide And iron (III) Phthalocyanine

2005
In this study we wish to report that t-butyl hydroperoxide is very efficient oxidant in the presence of iron(III)(phthalocyanine)Cl as catalyst for aromatization of 1, 4-DHPs (I), Scheme 1. These reactions are very clean and completed within ca. 30 minutes depending on substituents attached at phenyl ring.
Vinković, Vladimir, Litvić, Mladen, Filipan-Litvić, Mirela   +2 more
openaire   +1 more source

Oxidative and photooxidative phosphorylation by means of 1-phosphoryl-1, 4-dihydropyridines

Tetrahedron Letters, 1973
Shozo Matsumoto, Hiroaki Masuda, Ken-ichi Iwata, Oyo Mitsunobu   +3 more
openaire   +1 more source

Synthesis, properties, and cardiovascular activity of substituted 4-dihydropyridine-2(3H)-thiones

Pharmaceutical Chemistry Journal, 1988
A. A. Krauze, R. O. Vitolinya, M. R. Romanova, G. Ya. Dubur   +3 more
openaire   +1 more source