Results 121 to 130 of about 85,474,312 (231)

Lanthanide and asymmetric catalyzed syntheses of sterically hindered 4-isoxazolyl-1,4-dihydropyridines and 4-isoxazolyl-quinolones

, 2016
The Ytterbium (III) triflate catalyzed Hantzsch synthesis allows for the preparation of sterically hindered 4-isoxazolyl-1,4-dihydropyridines in moderate to good yields.
Li, Chun, Steiger, Scott A., Natale, Nicholas R., Campana, Charles F.   +3 more
core  

4-Heterotricyclic substituted 1,4-dihydropyridines with a potent selective bradycardic effect

, 1991
A series of 4-heterotricyclic substituted 1,4-dihydropyridines were prepared. The compounds were evaluated for inotropic, chronotropic and calcium antagonist properties.
Valenti P., Chiarini A., Bisi A., Rampa A., Budriesi R.   +4 more
core  

Use of dissolving metals in the partial reduction of pyridines: formation of 2-alkyl-1,2-dihydropyridines

, 2001
The partial reduction of a series of electron deficient pyridines to give both 1,2- and 2,5-dihydropyridines is described. The factors that lead to formation of such dihydropyridines are discussed and it was found that, generally, the presence of two ...
Andrew J. McRiner, Peter Sheldrake, Madeleine Helliwell, Timothy J. Donohoe   +3 more
core   +1 more source

General Synthesis Method of Hantzsch dihydropyridine Using Scrap Automobile Catalyst (SAC)

Journal of the Turkish Chemical Society Section B: Chemical Engineering
1,4-Dihydropyridine (DHP) derivatives are an important class of organic compounds known for their broad biological and pharmacological activities, particularly as calcium channel blockers, which make them valuable in medicinal chemistry.
Tuna Demirci
doaj   +1 more source

Exploring 1, 4-Dihydropyridines: Synthesis, Biological Activities, Therapeutic Potentials and Computational Studies

Abstract: 1, 4-dihydropyridines and their derivatives are the foremost notable class of Nitrogen-containing heterocyclic scaffolds and have been extensively used since they are occupying the highest position in the pharmaceutical industry because of its wider range of biological and medicinal uses.
Sodah, Karun, Khilnani, Dr. Veena, Sharma, Prerna   +2 more
openaire   +1 more source

Antimicrobial Activity of Some Derivatives of 1,4-Dihydropyridines

, 2020
Hantzsch reported the synthesis of functionalized 1,4-dihydropyridines via three-component condensation of an aromatic aldehyde, ketoester, and ammonium hydroxide.
Prabha Mehta, Prabha Verma
core  

A Review: Alternative Methods of Preparing 1, 4- Dihydropyridine Derivatives by Hantzsch Reaction

Journal of Scientific Research, 2021
Sandhya Patil, Leena Sarkar
openaire   +1 more source

Prior use of dihydropyridines is associated with reduced mortality among patients with sepsis in the intensive care unit: a retrospective cohort study using the MIMIC-IV database. [PDF]

Am J Transl Res
Wang Z, Zhou Q, Zhou M, Li P, Huang J, Li S, Wu C.   +6 more
europepmc   +1 more source

Hantzsch reaction: Recent advances in Hantzsch 1,4-dihydropyridines

, 2008
95-111Hantzsch reaction seems to be one of the earliest procedures for the production of pyridines. Later on, Hantzsch 1,4- dihydropyridines, which mimic NADH reduction process in vitro, have shown promising biological activities.
Kumar, Sanjay, Sandhu, Jagir S, Saini, Anil   +2 more
core  

"Store-and-Release" Strategy Enables Nickel-Catalyzed Deaminative Migratory Arylation of Aliphatic Amines. [PDF]

J Am Chem Soc
Kadam AA, Lee K, Liao Y, Knyazev A, Lourenço MJ, Tung P, Cauley AN, Dones JM, Oderinde MS, Kempson J, Roque JB.   +10 more
europepmc   +1 more source