Results 101 to 110 of about 85,474,312 (231)

One-pot synthesis of Dihydropyridines under solvent-free condition

, 2005
One-pot condensation of 1,3-dicarbonyl compounds with a range of aldehydes in the presence of ammonium bicarbonate was carried out under solvent-free condition at 70 degrees C to afford 1,4-dihydropyridines in 86%similar to 97 ...
Zhang, GL, Chinese Acad Sci, Chengdu Inst Biol, Chengdu 610041, Peoples R China., Cai, XH, Zhang, GL   +2 more
core  

Cyclization and N‑Iodosuccinimide-Induced Electrophilic Iodocyclization of 3‑Aza-1,5-enynes To Synthesize 1,2-Dihydropyridines and 3‑Iodo-1,2-dihydropyridines

, 2016
Metal-free cyclization and N-iodosuccinimide-induced electrophilic iodocyclization of readily available 3-aza-1,5-enynes have been developed. The reactions selectively give 1,2-dihydropyridines and 3-iodo-1,2-dihydropyridines involving an aza-Claisen ...
Dongping Wang (134633), Xiaoyi Xin (1545994), Xincheng Li (1546003), Fan Wu (43375), Boshun Wan (1546000)   +4 more
core   +1 more source

Synthesis, Molecular Docking and Preliminary in-Vitro Cytotoxic Evaluation of Some Substituted Tetrahydro-naphthalene (2',3',4',6'-Tetra-O-Acetyl-β-D-Gluco/-Galactopyranosyl) Derivatives

Molecules, 2012
A facile, convenient and high yielding synthesis of novel <em>S</em>-glycosides and <em>N</em>-glycosides incorporating 1,2,3,4-tetrahydronaphthalene and or 1,2-dihydropyridines moieties has been described. The aglycons <strong&
Maha S. Al-Mutairi, Ebtehal S. Al-Abdullah, Mogedda E. Haiba, Mohammed A. Khedr, Wafaa A. Zaghary   +4 more
doaj   +1 more source

Scaffold Hopping Provides Liver X Receptor Agonist With Preference for the β Subtype

ChemMedChem, Volume 21, Issue 19, 14 October 2026.
A scaffold hopping strategy was pursued to enhance the binding pocket engagement and β‐subtype selectivity of liver X receptor agonist 2. The resulting spirocyclic lead compound, (S)‐7, demonstrates superior potency, enhanced potency‐based selectivity for LXRβ, and improved microsomal stability over the existing scaffold.
Annette Kärcher, Fiona L. Motel, Felix F. Lillich, Astrid Kaiser, Ewgenij Proschak, Pascal Heitel   +5 more
wiley   +1 more source

Cyclization and N-Iodosuccinimide-Induced Electrophilic Iodocyclization of 3-Aza-1,5-enynes To Synthesize 1,2-Dihydropyridines and 3-Iodo-1,2-dihydropyridines

, 2013
Metal-free cyclization and N-iodosuccinimide-induced electrophilic iodocyclization of readily available 3-aza-1,5-enynes have been developed. The reactions selectively give 1,2-dihydropyridines and 3-iodo-1,2-dihydropyridines involving an aza-Claisen ...
Boshun Wan, Wu, Fan, Wan, Boshun, Dongping Wang, Xiaoyi Xin, Xincheng Li, Fan Wu, Li, Xincheng, Wang, Dongping, Xin, Xiaoyi   +9 more
core   +1 more source

Synthesis of new organic-inorganic hybride of Kit-6-NH2@Vanillin@α-methyleneacetophenone@ acridine-Cu(ꟾ) as a recoverable Lewis acid catalyst and its application for the synthesis of azoacridines

Results in Chemistry
Kit-6-NH2@Vanillin@ α-methyleneacetophenone @ acridine-Cu (ꟾ) nanoparticles were synthesized and were characterized completely. Then, the application of this new nano catalyst for the preparation of azo-derived dihydropyridines (acridines) via the ...
Leila Zare Fekri, Mohammad Nikpassand, Mogharab Torabi   +2 more
doaj   +1 more source

One-pot synthesis of 1,5-diketones from 3-acetyl-4-hydroxycoumarin and effective cyclization to unexpected 3,4-dihydropyridines

, 2018
A one-pot synthesis of new 4-hydroxycoumarin-based 1,5-diketones and effective cyclization to quite stable and unexpected 3,4-dihydropyridines has been developed.
Mohd Waheed, Naseem Ahmed, Mohammed Issa Alahmdi, Meshari A. Alsharif, Sayeed Mukhtar   +4 more
core   +1 more source

Synthesis and in vitro Evaluation of the Antimycobacterial Activity of N-aryl-1,4-dihydropyridine-3,5-dicarboxamides [PDF]

Journal of Sciences, Islamic Republic of Iran, 2012
Dihydropyridines (DHPs) with carboxamides in the 3 and 5 positions show anti-tuberculosis activity. The purpose of the present study was to synthesize new DHPs that would possibly possess anti-tuberculosis activity.
F. Mohammadpour
doaj  

Gallium(III) chloride as an efficient new catalyst for the production of Hantzsch 1 ,4-dihydropyridines

, 2009
Department of Chemistry, Punjabi University, Patiala-147 002, Punjab, india E-mail : j_sandhu2002@yahoo.com Manuscript received 16 March 2009, accepted 26 May 2009 Hantzsch 1,4-dihydropyridines (DHPs) are synthesized In good to excellent yields from aldehydes, 1,3-dicarbonyl compounds and ammonium acetate using gallium(lll) chloride which acts as ...
Dhruva Kumar, Saini, Anil, , Suresh, Sandhu, Jagir S.   +3 more
openaire   +1 more source

Synthesis of 1, 4-Dihydropyridine Derivatives using FeCl3 as Catalyst under Solvent-free Condition

Oriental Journal Of Chemistry, 2013
Chemistry of dihydropyridines in 1882 with Ar thur Hansh reports the β-keto ester, aldehydes and ammonia can be combined to form 1, 4-dihydropyridine was developed. Because of the many benefits of 1, 4-dihydropridine is presented and now as vital medicines to treat angina, high blood pressure and allergies have been introduced.
ABDORRAHMAN KEYHANI, FARHAD HATAMJAFARI
openaire   +1 more source