Results 81 to 90 of about 4,227 (116)

Synthesis and Biological Evaluation of New 1, 4-Dihydropyridines as Antihypertensives Agents in Rats

2003
New analogues of nifedipine, as a known calcium channel blocker, were synthesized by replacing the orthonitrophenyl group on position 4 with 1-(4-Nitrobenzyl)-5-imidazolyl or 2methylthio-1-(4-Nitrobenzyl)-5-imidazolyl substituent. Effects of the new synthesized compounds on blood pressure were studied at 15, 30 and 60 min after administration by ...
Jorjani, M, Rastegar, H, Roshanzamir, F, Varmazyari, M, Abdollahi, M, Zarghi, Afshin   +5 more
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Hybrid Docking-QSAR Studies of 1, 4-dihydropyridine-3, 5-Dicarboxamides as Potential Antitubercular Agents

Current Computer-Aided Drug Design, 2018
Tuberculosis is one of the main medical problems and some people are suffering still from this infectious disease. 1, 4-dihydropyridines are multi-target ligands that recently are recognized as anti-tubercular agents.In the current research, computational studies were conducted of some synthesized 1, 4- dihydropyridine-3, 5-dicarboxamides in non ...
Yasaman, Rasouli, Asghar, Davood
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Enantioselective analysis of 1, 4-dihydropyridine drugs by luquid chromatography

2004
The analyses for the following substances were performed: isradipine, nitrendipine, nicardipine, nisoldipine and felodipine. The most successful separations for the all investigated compounds were achieved on Chiralpak AD column that consist of amylose tris(3, 5-dimethylphenylcarbamat) as chiral selector.
Kalčić, Igor, Vinković, Vladimir, Litvić, Mladen   +2 more
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ChemInform Abstract: Synthesis, Properties, and Cardiovascular Activity of Substituted 4‐Dihydropyridine‐2(3H)‐thiones.

ChemInform, 1988
AbstractThe dihydropyridinethiolates (V), prepared by common cyclization reactions, are converted to the thiones (VIII), the betaines (IX), and the sodium salts (X).
A. A. KRAUZE, R. O. VITOLIN'A, M. R. ROMANOVA, G. YA. DUBUR   +3 more
openaire   +1 more source

Aromatization of 1, 4-dihydropyridine derivatives

2006
Pripravljeno je ukupno 29 različito supstituiranih 1, 4-dihidropiridinskih derivata korištenjem nekoliko varijanti Hantzschove kondenzacije. Prilikom pokušaja priprave derivata 35 sa prisutnom metoksi skupinom u ortho-položaju arilne grupe, korištenjem Hantzschove metode sa dva mola aminokrotonatnog estera, izoliran je literaturno novi spoj 49 kao ...
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Enantioselective and diastereoselective preparation of 1, 4-dihydropyridines

2004
Ispitane su različite metode za pripravu enantiomerno čistih 1, 4-dihidropiridinskih spojeva (1, 4-DHP). Rezultati pokazuju da se ovaj tip spojeva dobiva vrlo teško u enantiomerno čistom obliku i da ne postoji jedna općenita metoda za njihovu pripravu.
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Synthesis and pharmacological activity of 4-aryl-l,4-dihydropyridines

Pharmaceutical Chemistry Journal, 1982
V. V. Kastron, G. Ya. Dubur, R. O. Vitolin', A. A. Kimenis, M. Ya. Selga, N. V. Kondratenko, L. M. Yagupol'skii, D. Ya. Tirzite, Yu. A. Fialkov, S. V. Shelezhenko   +9 more
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Synthese de diacyl-1,4 alcoyl-4 dihydropyridines

Tetrahedron Letters, 1969
P.M. Atlani, J.F. Biellmann
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Chiral Phosphoric Acid Catalyzed Enantioselective Desymmetrization of 1,4‐Dihydropyridines by C(sp3)−H Bromination

Angewandte Chemie - International Edition, 2022
Guang-Xun Li
exaly  

Oxidative and photooxidative phosphorylation by means of 1-phosphoryl-1, 4-dihydropyridines

Tetrahedron Letters, 1973
Shozo Matsumoto, Hiroaki Masuda, Ken-ichi Iwata, Oyo Mitsunobu   +3 more
openaire   +1 more source