Results 81 to 90 of about 5,843 (268)

Study of the anti-exudative activity of new 3-cyano-1,4- dihydropyridines, cyanotioacetamide derivatives, on the model of acute formalin edema

Сибирский научный медицинский журнал
The inflammatory process accompanies most of the pathologies and requires pharmacological correction. In spite of significant achievements of scientists in the field of medicine and pharmacology, existing steroid and nonsteroidal antiinflammatory drugs ...
A. V. Bochev, E. Yu. Bibik, S. G. Krivokolysko, K. A. Frolov   +3 more
doaj   +1 more source

Synthetic routes within the parameters of green chemistry for 1,4-dihydropyrinides production [PDF]

, 2016
Las 1,4-dihidropiridinas (1,4-DHPs) son compuestos heterocíclicos de gran importantes en la industria farmacológica, por lo tanto es uno de los objetivos sintéticos más atractivos de la química orgánica.
Gutiérrez, Luisa Fernanda, Prieto Suarez, Gloria Astrid   +1 more
core  

Ceria-Molybdenum Mix Metal Oxide: A Mild and Efficient Recyclable Catalyst for One-Pot Synthesis of Polyhydroquinoline via Hantzsch Reaction [PDF]

, 2020
In laboratory, ceria-molybdenum mix metal oxide catalyst was synthesized by using simple grinding method and characterized by FT-IR, XRD, SEM, and EDX. Catalytic activities of catalyst were testified in Hantzsch condensation reaction for the synthesis of
Bansode, Nilam D., Gadekar, Sachin P., Gaikwad, Suresh T., Lande, Machhindra K.   +3 more
core   +1 more source

Antioxidant supplementation blunts the proteome response to 3 weeks of sprint interval training preferentially in human type 2 muscle fibres

The Journal of Physiology, EarlyView.
Abstract figure legend Sprint interval training (SIT) is a popular time‐efficient type of endurance training. Healthy young men performed nine SIT sessions (4–6 × 30 s all‐out cycling sprints) over 3 weeks while being supplemented with antioxidants (high doses of vitamins C and E) or placebo. Muscle biopsies taken before and after the first SIT session
Victoria L. Wyckelsma, Marta Murgia, Sigitas Kamandulis, Stefano Gastaldello, Marius Brazaitis, Audrius Snieckus, Nerijus Eimantas, Mati Pääsuke, Sebastian Edman, William Apro, Daniel C. Andersson, Håkan Westerblad, Tomas Venckunas   +12 more
wiley   +1 more source

SYNTHESIS OF 4-(1-BENZYL-5-IMIDAZOLYL)-1,4-DIHYDROPYRIDINES [PDF]

Journal of Sciences, Islamic Republic of Iran, 2002
The o-nitrophenyl group at position 4 of dihydropyridine of nifedipine analogues was replaced with 2-alkylthio-1-benzyl-5-imidazolyl substituent. Starting from dihydroxyacetone 2-alkythio-1-benzyl- 5-formyl imidazole (3) was first synthesized which was ...
doaj  

Nucleophilic dearomatization of 4-aza-6-nitrobenzofuroxan by CH acids in the synthesis of pharmacology-oriented compounds

Beilstein Journal of Organic Chemistry, 2017
4-Aza-6-nitrobenzofuroxan (ANBF) reacts with 1,3-dicarbonyl compounds and other CH acids to give carbon-bonded 1,4-adducts – 1,4-dihydropyridines fused with furoxan ring.
Alexey M. Starosotnikov, Dmitry V. Shkaev, Maxim A. Bastrakov, Ivan V. Fedyanin, Svyatoslav A. Shevelev, Igor L. Dalinger   +5 more
doaj   +1 more source

Silica gel supported chromium trioxide: An effective reagent for aromatization of 4- alkyl/aryl-I, 4-dihydropyridines [PDF]

, 1998
817 ...
Jaisinghani, Harsha, Khadilkar, Bhushan, Khare, Atul   +2 more
core  

Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes

The Journal of Physiology, EarlyView.
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière, Thomas Boulin, Maëlle Jospin, Alexandre Janin, Gilles Millat, Philippe Chevalier, Olga Andrini   +6 more
wiley   +1 more source

UNC45B Reduction With Aging: A Myofiber‐Intrinsic Promoting Factor for Sarcopenia

Aging Cell, Volume 25, Issue 5, May 2026.
Aging reduces Unc45b expression in fast‐twitch muscle, concomitant with reduction in muscle contractile capacity and muscle mass in mice. Unc45b deficiency initially reduces depolarization‐induced force, followed by a decline in fast‐twitch muscle mass in adult mice.
Taiga Mishima, Taiga Nagamune, Saori Tada, Daiki Watanabe, Nao Tokuda, Takashi Yamada, Akiko Hashimoto‐Hachiya, Sayaka Higo‐Yamamoto, Kohei Kido, Noriyuki Nagaoka, Aoi Ikedo, Yuuki Imai, Ryo Fujita, Seiya Mizuno, Satoru Takahashi, Katsutaka Oishi, Satoru Ato, Riki Ogasawara   +17 more
wiley   +1 more source

Assessment of possible biomarkers of individual representatives of 1,4-dihydropyridines by methods of molecular docking and predictor analysis

Research Results in Pharmacology
Introduction: Some of the promising classes of chemical compounds for research are 1,4-dihydropyridines, which have potential biological activity and low toxicity.
Elena Yu. Bibik, Ivan A. Nekrasa, Vladislav V. Bibik, Konstantin A. Frolov, Sergey G. Krivokolysko   +4 more
doaj   +1 more source