Results 61 to 70 of about 5,843 (268)
HgO/I2 as an Efficient Reagent for the Oxidative Aromatization of Hantzsch 1-NH, 4-Dihydropyridines under Mild and Heterogeneous Conditions [PDF]
, 2015 A variety of Hantzsch 1-NH, 4-dihydropyridines were efficiently aromatized to the corresponding pyridine derivatives by treatment with HgO/I2 reagent in dichloromethane under mild and heterogeneous conditions in good to excellent yields at room ...
Habibi, MH +2 more
core +1 more source
SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF 1,4-DIHYDROPYRIDINE DERIVATIVE [PDF]
, 2017 A series of substituted 1,4-dihydopyridine derivatives (SC1-SC10) was synthesized via condensation of acetoacetanilide /4-chloro acetoacetanilide and substituted benzaldehyde in methanol with excess amount of ammonia.
Chourey, Shikha +2 more
core +2 more sources
Inherited metabolic epilepsies–established diseases, new approaches
Epilepsia Open, EarlyView.Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
Preliminary Methodology on the Integrated Chiroptical Spectroscopy of Polymorphic Chiral Compounds [PDF]
, 2016 摘要 与手性立体化学和手性技术相关的研究不仅在化学和医药领域不可或缺，而且在材料、环境和生命科学等领域也有重要应用。本文以手性1，4-二氢吡啶类(1，4-DHPs)衍生物尼莫地平和氨氯地平，手性保健品氨基糖类，以及手性聚集诱导发光(AIE)化合物为研究对象，开展X-射线单晶结构分析、X-射线粉末衍射(XRD)、晶型、绝对构型关联、电子圆二色(ECD)和振动圆二色(VCD)光谱等手性检测方法学研究。本论文各章节的主要构成为： 第一章为绪论，着重强调了晶型手性药物和手性保健品的重要性及研究意义 ...
郭栋
core
EVALUATION OF ANTI-ANXIETY EFFECT OF NIFEDIPINE COMPARED TO DIAZEPAM IN SWISS ALBINO MICE USING BEHAVIOURAL MODELS [PDF]
, 2020 Objective: The present study was undertaken to evaluate the acute and chronic anxiolytic effects of nifedipine in comparison to diazepam using in Swiss Albino mice using two behavioral models. Methods: 30 Swiss albino mice were divided into 5 groups with
SHANKPAL, PRAMOD, SURVE, SHWETA
core +1 more source
Medicinal Research Reviews, EarlyView.ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur +6 more
wiley +1 more source
Sleep Research, EarlyView.Abstract Study objectives To investigate the use of automated analysis to detect heart rate accelerations (HRAs) to screen for sleep‐disordered breathing (SDB) among patients who use chronotropic medications. Methods Nocturnal polysomnography (NPSG) recordings from 933 participants in the Sleep Heart Health Study were analyzed using an automated method
Nabila Ahmed +11 more
wiley +1 more source
The Chemical Record, EarlyView.This review highlights recent advances in the use of organic carbonates, dimethyl carbonate (DMC), diethyl carbonate (DEC), and propylene carbonate (PC), as solvents in organic synthesis. Based on over seventy studies from the past 6 years, it shows their application in different organic reaction types, emphasizing their role in safer and more ...
Gabriela T. Quadros +5 more
wiley +1 more source
Synthesis and anticonvulsant activity of some 1,4-dihydropyridine derivatives [PDF]
, 2021 A series of asymmetrical 4-alkyl/aryl-2,6-dimethyl-3-N-(aryl/heteroaryl)-carbamoyl-5-ethoxycarbonyl-1, 4-dihydropyridines 3a-d and symmetrical 4-alkyl/aryl-2,6-dimethyl-3,5-bis-(ethoxycarbonyl)-1,4-dihydropyridines 4a and 4b have been prepared by the ...
Begum, Safia , Sirisha, Kalam
core +4 more sources
Dihydropyridines as Calcium Channel Blockers: An Overview [PDF]
, 2017 Cardiovascular disease remains one of the leading causes of death in the United States. It is estimated that 1 in every 3 American adults suffer from high blood pressure.
Bandyopadhyay, Debasish +2 more
core +1 more source