Results 41 to 50 of about 5,843 (268)

EVALUATION OF HEMATOTOXICITY OF NEW DERIVATIVES OF CONDENSED 3-AMINOTHIENO[2,3-B]PYRIDINES AND 1,4-DIHYDROPYRIDINES WITH HIGH ANALGESIC ACTIVITY

Паёми Сино, 2023
Objective: To assess changes in blood parameters in rats after a two-week administration of the most commonly used clinically NSAIDs and new derivatives of the 3-aminothieno[2,3-b]pyridine and 1,4-dihydronicotinamide series with the most pronounced ...
I.V. BIBIK, A.A. PANKOV, K.A. FROLOV, V.V. DOTSENKO, S.G. KRIVOKOLYSKO, E.YU. BIBIK   +5 more
doaj   +1 more source

Recent Progresses in the Catalytic Stereoselective Dearomatization of Pyridines

Molecules, 2023
1,2- and 1,4-dihydropyridines and N-substituted 2-pyridones are very important structural motifs due to their synthetic versatility and vast presence in a variety of alkaloids and bioactive molecules.
Lucrezia Margherita Comparini, Mauro Pineschi   +1 more
doaj   +1 more source

The effect of dissolution medium, rotation speed and compaction pressure on the intrinsic dissolution rate of amlodipine besylate, using the rotating disk method [PDF]

, 2014
The aim of this study was to evaluate the effect of dissolution medium, rotation speed and compaction pressure on the intrinsic dissolution rate (IDR) of the antihypertensive drug amlodipine besylate, using the rotating disk method.
Ferraz, Humberto Gomes, Giorgetti, Leandro, Issa, Michele Georges   +2 more
core   +4 more sources

Additive‐Manufactured, Multifunctional Bioreactor Technology for Dynamic Culture of 3D Bioprinted Tissue Models

Advanced Materials Technologies, EarlyView.
We introduce an additively manufactured bioreactor with a perfusion flow system and integrated temperature and pH sensors for skeletal muscle tissue biofabrication. The bioreactor's performance was evaluated by assessing the viability, spreading of the myoblast cells in a printed scaffold, and contraction of the isolated murine musculi interossei ...
Lys Sprenger, Johann Schorzmann, Hsuan‐Heng Lu, Muhammad Osama, Julian Bauer, Michael Haug, Oliver Friedrich, Aldo R. Boccaccini, Frank Döpper, Sahar Salehi   +9 more
wiley   +1 more source

Síntese de compostos híbridos dihidropiridina-dihidropiridina via Cicloadição 1,3-dipolar azida-alceno catalisada por cobre (CuAAC) [PDF]

, 2022
As relações entre proteínas, estruturas químicas e propriedades semelhantes a drogas fornecem uma base para o desenvolvimento de uma abordagem probabilística para a descoberta de drogas que pode ser explorada para aumentar a produtividade da pesquisa ...
Cesar, Camila Duque
core  

RNA-Seq reveals differential expression profiles and functional annotation of genes involved in retinal degeneration in Pde6c mutant Danio rerio. [PDF]

, 2020
BACKGROUND: Retinal degenerative diseases affect millions of people and represent the leading cause of vision loss around the world. Retinal degeneration has been attributed to a wide variety of causes, such as disruption of genes involved in ...
Bouras, Adam, Huang, Hu, Lennikov, Anton, Saddala, Madhu Sudhana   +3 more
core   +1 more source

Deep Extractive Oxidative Desulfurization of Model Oil/Crude Oil using Different Keggin Heteropoly Acids Supported on K10 Montmorillonite [PDF]

, 2023
This study investigated the catalytic performance of three polyoxometalates (H3PMo12O40 (PMo), H3PW12O40 (PW), and H4SiW12O40 (SiW)) supported on montmorillonite K10 for oxidative desulfurization (ODS) of thiophenic model oil, crude oil, and gasoline ...
Ezzat Rafiee, Gholam Reza Moradi, Sadegh Sahraei   +2 more
core   +1 more source

Stabilization of Single Metal Atoms on Graphitic Carbon Nitride: Synthetic Strategies and Emerging Applications

Advanced Science, EarlyView.
This review highlights recent advancements in stabilizing single metal atoms on graphitic carbon nitride emphasizing innovative synthesis strategies and emerging applications in electrocatalysis, photocatalysis and organic transformations, along with key challenges and future perspective. Abstract Emerging as a new frontier in catalysis science, single‐
Wenyao Zhang, Junjie Cui, Zhenjie Yao, Boyuan Zhu, Nithinraj Panangattu Dharmarajan, Ajayan Vinu, Junwu Zhu   +6 more
wiley   +1 more source

Effects of dietary diludine supplementation on growth, proximate composition, muscle and texture structure of rainbow trout juveniles [PDF]

, 2018
A feeding trial which lasted for eight weeks was conducted to investigate the effects of diludine, a growth promoter, on feed efficiency, muscle structure and proximate composition of juvenile rainbow trout. Diludine was added at 0.0(D0) 0.2(D1), 0.5(D2)
Gürkan, M., Hisar, O., Hisar, S.A., Karaoğlu, M.M., Kaya, H., Yanik, T.   +5 more
core  

Beyond right or wrong: How partial credit scoring on multiple‐choice questions improves student performance and assessment perceptions

British Journal of Clinical Pharmacology, EarlyView.
Aims In this study, we examined the effects of assigning partial credit to selected answer choices on student performance and perceptions in a pharmacology course using Type A multiple‐choice questions (MCQs). Methods Partial credit scoring was incorporated into quizzes and exams in a 10‐week pharmacology course for postbaccalaureate premedical ...
Stephen D. Schneid, Chris Armour, Katharina Brandl   +2 more
wiley   +1 more source