Objective: To assess changes in blood parameters in rats after a two-week administration of the most commonly used clinically NSAIDs and new derivatives of the 3-aminothieno[2,3-b]pyridine and 1,4-dihydronicotinamide series with the most pronounced ...
I.V. BIBIK +5 more
doaj +1 more source
Recent Progresses in the Catalytic Stereoselective Dearomatization of Pyridines
1,2- and 1,4-dihydropyridines and N-substituted 2-pyridones are very important structural motifs due to their synthetic versatility and vast presence in a variety of alkaloids and bioactive molecules.
Lucrezia Margherita Comparini +1 more
doaj +1 more source
RNA-Seq reveals differential expression profiles and functional annotation of genes involved in retinal degeneration in Pde6c mutant Danio rerio. [PDF]
BACKGROUND: Retinal degenerative diseases affect millions of people and represent the leading cause of vision loss around the world. Retinal degeneration has been attributed to a wide variety of causes, such as disruption of genes involved in ...
Bouras, Adam +3 more
core +1 more source
Aims In this study, we examined the effects of assigning partial credit to selected answer choices on student performance and perceptions in a pharmacology course using Type A multiple‐choice questions (MCQs). Methods Partial credit scoring was incorporated into quizzes and exams in a 10‐week pharmacology course for postbaccalaureate premedical ...
Stephen D. Schneid +2 more
wiley +1 more source
Synthesis of 1,4-Dihydropyridines Bearing a Carbamate Moiety on the 4-Position
A good range of 1,4-dihydropyridines bearing a carbamate moiety on the 4-position were synthesized from the primary reaction of different hydroxyaldehydes with phenyl isocyanates and the subsequent reaction of the obtained carbamates with methyl ...
Davood Habibi +2 more
doaj +1 more source
Effects of dietary diludine supplementation on growth, proximate composition, muscle and texture structure of rainbow trout juveniles [PDF]
A feeding trial which lasted for eight weeks was conducted to investigate the effects of diludine, a growth promoter, on feed efficiency, muscle structure and proximate composition of juvenile rainbow trout. Diludine was added at 0.0(D0) 0.2(D1), 0.5(D2)
Gürkan, M. +5 more
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Deep Extractive Oxidative Desulfurization of Model Oil/Crude Oil using Different Keggin Heteropoly Acids Supported on K10 Montmorillonite [PDF]
This study investigated the catalytic performance of three polyoxometalates (H3PMo12O40 (PMo), H3PW12O40 (PW), and H4SiW12O40 (SiW)) supported on montmorillonite K10 for oxidative desulfurization (ODS) of thiophenic model oil, crude oil, and gasoline ...
Ezzat Rafiee +2 more
core +1 more source
One-Pot Synthesis of 1, 4-Dihydropyridines in PEG Under Catalyst-Free Conditions [PDF]
A simple, inexpensive, and efficient one-pot synthesis of 1,4-dihydropyridine via Hantzsch reaction was achieved in good to excellent yields under catalyst free conditions by using PEG400 as solvent. In this reaction, PEG-400 was used as the solvent, which has such advantages: absolutely nontoxic, inexpensive, thermally stable, recoverable and easy to ...
Shuwei Zhang +5 more
openaire +1 more source
Aim A prior non‐randomized study suggests that potassium supplementation may improve survival among furosemide initiators, and a randomized trial suggests that salt substitutes containing potassium might lower stroke risk. We conducted a retrospective cohort study using health‐care data to confirm or refute these associations among new users of ...
Thanh Phuong Pham Nguyen +8 more
wiley +1 more source
Síntese de compostos híbridos dihidropiridina-dihidropiridina via Cicloadição 1,3-dipolar azida-alceno catalisada por cobre (CuAAC) [PDF]
As relações entre proteínas, estruturas químicas e propriedades semelhantes a drogas fornecem uma base para o desenvolvimento de uma abordagem probabilística para a descoberta de drogas que pode ser explorada para aumentar a produtividade da pesquisa ...
Cesar, Camila Duque
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