Oxidation of Hantzsch 1,4- Dihydropyridines to Pyridines with Thallium Triacetate [PDF]
Hantzsch 1, 4-dihydropyridines (1,4-DHPs) can be oxidized to the corresponding pyridine derivatives by thallium triacetate in high yields.
Mohammad Mahmoodi Hashemi +2 more
doaj
An Efficient Method for The Synthesis of Dihydropyridine by Hantzsch Reaction with Fe/SiO2 Nano Heterogeneous Catalysts [PDF]
An efficient method for the synthesis of dihydropyridines (DHPs) by Hantzsch reaction with Fe/SiO2 heterogeneous catalysts was developed. The Fe/SiO2 catalysts was prepared by impregnation method.
Nehemia, P. N. +2 more
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Anticonvulsant effects of nimodipine alone and combination with phenytoin on MES induced seizures [PDF]
Background: To evaluate the anticonvulsant activity of Nimodipine alone and in combination with Phenytoin, in MES induced seizures.Methods: The study was conducted in mice and MES seizure was induced by Techno electroconvulsometer. In first part of study,
Jain, Ashish, Jain, Raina
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Synthesis of 2-Mono and 2,6-Disubstituted Methyl-1,4-Dihydropyridines [PDF]
The 2-mono and 2,6-disubstituted methyl-1,4-dihydropyridines were synthesized by reaction of morpholine, thiophenol, 8-hydroxyquinoline, 2-naphthol and 2-mercopto-1-methyl imidazole with the 2-mono bromo and 2,6-dibromo-1,4-dihidropyridines.
Yousef Rastgar Mirzaei +1 more
doaj
Cytotoxic effect of some 1, 4-dihydropyridine derivatives containing nitroimidazole moiety.
The 1,4-dihydropyridine (DHP) derivatives are a known class of calcium channel blockers. Some derivatives of DHP showed significant cytotoxicity. It was shown that this effect may not be the result of interaction with Ca(2+) channels. In this study, we performed an investigation about the intrinsic cytotoxicity of some derivatives of DHP containing ...
Miri, Ramin +6 more
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New Organocatalytic Asymmetric Synthesis of Highly Substituted Chiral 2-Oxospiro-[indole-3,4′- (1′,4′-dihydropyridine)] Derivatives [PDF]
Herein, we report our preliminary results concerning the first promising asymmetric synthesis of highly functionalized 2-oxospiro-[indole-3,4′-(1′,4′-dihydropyridine)] via the reaction of an enamine with isatylidene malononitrile derivatives in the presence of a chiral base organocatalyst.
Fernando Auria-Luna +4 more
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One-Pot Synthesis of 1, 4-Dihydropyridines in PEG Under Catalyst-Free Conditions [PDF]
A simple, inexpensive, and efficient one-pot synthesis of 1,4-dihydropyridine via Hantzsch reaction was achieved in good to excellent yields under catalyst free conditions by using PEG400 as solvent. In this reaction, PEG-400 was used as the solvent, which has such advantages: absolutely nontoxic, inexpensive, thermally stable, recoverable and easy to ...
Shuwei Zhang +5 more
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Anticancer Activity of 4-Aryl-1,4-Dihydropyridines
We have synthesized 22 symmetric and asymmetric 4-aryl-1,4-dihydropyridines (1,4-DHPs) by a “green” microwave-assisted one-pot multicomponent Hantzsch reaction and evaluated their cytotoxicity to three human cancer cell lines regarding U-251MG (human ...
Thaís A. S. Oliveira +5 more
doaj +1 more source
An efficient Hantzsch synthesis of 1,4-dihydropyridines using p-toluenesulfonic acid under solvent-free condition [PDF]
An efficient Hantzsch synthesis of various substituted 1,4-dihydropyridines from an aldehyde, a β-dicarbonyl compound and ammonium acetate using p-toluenesulfonic acid in a solvent-free condition in the absence of any other co ...
Masoud Nasr-Esfahani +2 more
doaj +1 more source
Sol - Gel synthesis and characterization of magnesium peroxide nanoparticles [PDF]
Magnesium peroxide is an excellent source of oxygen in agriculture applications, for instance it is used in waste management as a material for soil bioremediation to remove contaminants from polluted underground water, biological wastes treatment to ...
Chan, Yen
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