Results 31 to 40 of about 85,474,312 (231)

Facile, Regioselective [4 + 2] Cycloaddition Involving 1-Aryl-4-phenyl-1-azadienes and Allenic Esters:  An Efficient Route to Novel Substituted 1-Aryl-4-phenyl-1,4-dihydropyridines

open access: yes, 2016
1-Aryl-4-phenyl-1-azadienes undergo facile, regioselective [4 + 2] cycloaddition to the C2,C3 π-bond of allenic esters in refluxing benzene, and the formed adducts undergo a 1,3-H shift to afford novel 2-alkyl-1-aryl-3-ethoxycarbonyl-4-phenyl-1,4 ...
Sumanjit Kaur (3063594)   +7 more
core   +1 more source

Substituent Effect on the Photolability of 4-Aryl-1,4-Dihydropyridines [PDF]

open access: yes, 2014
Artículo de publicación ISIThe electronic nature of substituents attached to the 4-aryl moiety of 1,4-dihydropyridines strongly affects the photophysical and photochemical behavior of these family of compounds.
García, Cristóbal   +7 more
core   +1 more source

Rapid, Greener and One-pot Four Component Synthesis of 1, 4-Dihydropyridine Derivatives

open access: yesAnalytical Chemistry Letters, 2022
In this current research framework, an efficient greener synthesis has been developed for new pyridine derivatives using one-pot four-component reaction. We have synthesized a new series of 1,4-dihydropyridine derivatives in excellent yield via telescopic multicomponent reaction among the aldehyde, malononitrile, anilines and diethyl ...
Jadeja, Kiranba F., Joshi, Hitendra S.
openaire   +1 more source

Unique Structure−Activity Relationship for 4-Isoxazolyl-1,4-dihydropyridines

open access: yes, 2016
A series of 4-isoxazolyl-1,4-dihydropyridines (IDs) were prepared and characterized, and their interaction with the calcium channel was studied by patch clamp analysis.
Alex Blumenfeld (2306734)   +7 more
core   +1 more source

Four-Component Fusion Protocol with NiO/ZrO2 as a Robust Recyclable Catalyst for Novel 1,4-Dihydropyridines

open access: yes, 2019
Nickel oxide loaded on zirconia (NiO/ZrO2) as an expedient catalyst is reported for the synthesis of 18 unsymmetrical 1,4-dihydropyridine derivatives.
Werner E. van Zyl (2966031)   +3 more
core   +3 more sources

Synthesis of 2-Mono and 2,6-Disubstituted Methyl-1,4-Dihydropyridines [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 1997
The 2-mono and 2,6-disubstituted methyl-1,4-dihydropyridines were synthesized by reaction of morpholine, thiophenol, 8-hydroxyquinoline, 2-naphthol and 2-mercopto-1-methyl imidazole with the 2-mono bromo and 2,6-dibromo-1,4-dihidropyridines.
Yousef Rastgar Mirzaei   +1 more
doaj  

Anticancer Activity of 4-Aryl-1,4-Dihydropyridines

open access: yesFuture Pharmacology
We have synthesized 22 symmetric and asymmetric 4-aryl-1,4-dihydropyridines (1,4-DHPs) by a “green” microwave-assisted one-pot multicomponent Hantzsch reaction and evaluated their cytotoxicity to three human cancer cell lines regarding U-251MG (human ...
Thaís A. S. Oliveira   +5 more
doaj   +1 more source

Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities

open access: yesAGING MEDICINE, EarlyView.
Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley   +1 more source

An efficient Hantzsch synthesis of 1,4-dihydropyridines using p-toluenesulfonic acid under solvent-free condition [PDF]

open access: yesMaejo International Journal of Science and Technology, 2014
An efficient Hantzsch synthesis of various substituted 1,4-dihydropyridines from an aldehyde, a β-dicarbonyl compound and ammonium acetate using p-toluenesulfonic acid in a solvent-free condition in the absence of any other co ...
Masoud Nasr-Esfahani   +2 more
doaj   +1 more source

Face-Selective Addition to a Cation−π Complex of a Pyridinium Salt:  Synthesis of Chiral 1,4-Dihydropyridines

open access: yes, 2016
Selective shielding of one side of the pyridinium face by way of intramolecular cation−π complex formation enabled nucleophiles to attack only from the non-shielded side, and consequently, chiral 1,4-dihydropyridines were produced stereoselectively with ...
Shinji Yamada (1488268)   +1 more
core   +1 more source

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