Results 31 to 40 of about 85,474,312 (231)
1-Aryl-4-phenyl-1-azadienes undergo facile, regioselective [4 + 2] cycloaddition to the C2,C3 π-bond of allenic esters in refluxing benzene, and the formed adducts undergo a 1,3-H shift to afford novel 2-alkyl-1-aryl-3-ethoxycarbonyl-4-phenyl-1,4 ...
Sumanjit Kaur (3063594) +7 more
core +1 more source
Substituent Effect on the Photolability of 4-Aryl-1,4-Dihydropyridines [PDF]
Artículo de publicación ISIThe electronic nature of substituents attached to the 4-aryl moiety of 1,4-dihydropyridines strongly affects the photophysical and photochemical behavior of these family of compounds.
García, Cristóbal +7 more
core +1 more source
Rapid, Greener and One-pot Four Component Synthesis of 1, 4-Dihydropyridine Derivatives
In this current research framework, an efficient greener synthesis has been developed for new pyridine derivatives using one-pot four-component reaction. We have synthesized a new series of 1,4-dihydropyridine derivatives in excellent yield via telescopic multicomponent reaction among the aldehyde, malononitrile, anilines and diethyl ...
Jadeja, Kiranba F., Joshi, Hitendra S.
openaire +1 more source
Unique Structure−Activity Relationship for 4-Isoxazolyl-1,4-dihydropyridines
A series of 4-isoxazolyl-1,4-dihydropyridines (IDs) were prepared and characterized, and their interaction with the calcium channel was studied by patch clamp analysis.
Alex Blumenfeld (2306734) +7 more
core +1 more source
Nickel oxide loaded on zirconia (NiO/ZrO2) as an expedient catalyst is reported for the synthesis of 18 unsymmetrical 1,4-dihydropyridine derivatives.
Werner E. van Zyl (2966031) +3 more
core +3 more sources
Synthesis of 2-Mono and 2,6-Disubstituted Methyl-1,4-Dihydropyridines [PDF]
The 2-mono and 2,6-disubstituted methyl-1,4-dihydropyridines were synthesized by reaction of morpholine, thiophenol, 8-hydroxyquinoline, 2-naphthol and 2-mercopto-1-methyl imidazole with the 2-mono bromo and 2,6-dibromo-1,4-dihidropyridines.
Yousef Rastgar Mirzaei +1 more
doaj
Anticancer Activity of 4-Aryl-1,4-Dihydropyridines
We have synthesized 22 symmetric and asymmetric 4-aryl-1,4-dihydropyridines (1,4-DHPs) by a “green” microwave-assisted one-pot multicomponent Hantzsch reaction and evaluated their cytotoxicity to three human cancer cell lines regarding U-251MG (human ...
Thaís A. S. Oliveira +5 more
doaj +1 more source
Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities
Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley +1 more source
An efficient Hantzsch synthesis of 1,4-dihydropyridines using p-toluenesulfonic acid under solvent-free condition [PDF]
An efficient Hantzsch synthesis of various substituted 1,4-dihydropyridines from an aldehyde, a β-dicarbonyl compound and ammonium acetate using p-toluenesulfonic acid in a solvent-free condition in the absence of any other co ...
Masoud Nasr-Esfahani +2 more
doaj +1 more source
Selective shielding of one side of the pyridinium face by way of intramolecular cation−π complex formation enabled nucleophiles to attack only from the non-shielded side, and consequently, chiral 1,4-dihydropyridines were produced stereoselectively with ...
Shinji Yamada (1488268) +1 more
core +1 more source

