Results 21 to 30 of about 85,474,312 (231)

Enaminones in a multicomponent synthesis of 4-aryldihydropyridines for potential applications in photoinduced intramolecular electron-transfer systems

Beilstein Journal of Organic Chemistry, 2012
An efficient three component reaction with enaminones, primary amines and aldehydes resulted in easy access to 1,4-dihydropyridines with different substituents at the 1-, 3-, 4- and 5-positions.
Nouria A. Al-Awadi, Maher R. Ibrahim, Mohamed H. Elnagdi, Elizabeth John, Yehia A. Ibrahim   +4 more
doaj   +1 more source

Rearrangement of o-Nitrobenzaldehyde in the Hantzsch Reaction

Molecules, 2001
The reaction of 5-hydroxy-2-nitrobenzaldehyde with ethyl acetoacetate in ammonia gave the two expected isomeric 1,4- and 1,2-dihydropyridines resulting from the normal Hantzsch reaction.
R. Martínez, R. López- Castañares, A. Velázquez, A. Ramírez, I. Martínez, I. Menconi, H. Santillán, E. Angeles   +7 more
doaj   +1 more source

N,N'-Ethylene-bis(benzoylacetoniminato) Copper (II), Cu(C22H22N2O2), a New Reagent for Aromatization of Hantzsch 1,4-Dihydropyridines

Molecules, 2007
A variety of Hantzsch 1,4-dihydropyridines were oxidized to their corresponding pyridines in high yields in the presence of Cu(C22H22N2O2) in refluxing acetic acid.
Majid M Heravi, Saeed Dehghanpour, Fatemeh Derikvand   +2 more
doaj   +1 more source

Electron Donor–Acceptor Complex Catalysis in Synthetic Chemistry

Angewandte Chemie, EarlyView.
Electron donor–acceptor (EDA) complexes are moving beyond stoichiometric photoactivation toward catalytic platforms for radical generation. Productive EDA catalysis requires coordinated donor–acceptor association, charge‐transfer excitation, radical reactivity, and vcatalyst turnover.
Tristan von Münchow, Andrea Palone, Jonathan Samuel Trimble, Paolo Melchiorre   +3 more
wiley   +2 more sources

Direct Aminolysis of Ethoxycarbonylmethyl 1,4-Dihydropyridine-3-carboxylates

Molecules, 2015
The ethoxycarbonylmethyl esters of 1,4-dihydropyridines were directly converted into carbamoylmethyl esters in the presence of 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD) in good to excellent yields under mild conditions.
Brigita Vigante, Martins Rucins, Aiva Plotniece, Karlis Pajuste, Iveta Luntena, Brigita Cekavicus, Egils Bisenieks, Rufus Smits, Gunars Duburs, Arkadij Sobolev   +9 more
doaj   +1 more source

Cardiovascular Profile of Xanthone-Based 1,4 Dihydropyridines Bearing a Lidoflazine Pharmacophore Fragment

Molecules, 2018
As a follow-up to our previous studies on differently substituted 1,4-dihydropyridines endowed with a peculiar cardiac selectivity, in this paper, a small series of hybrid compounds bearing the pharmacophore fragment of lidoflazine in position 2 or 3 on ...
Alessandra Bisi, Matteo Micucci, Silvia Gobbi, Federica Belluti, Roberta Budriesi, Angela Rampa   +5 more
doaj   +1 more source

Cytotoxic effect of some 1, 4-dihydropyridine derivatives containing nitroimidazole moiety.

Iranian journal of pharmaceutical research : IJPR, 2011
The 1,4-dihydropyridine (DHP) derivatives are a known class of calcium channel blockers. Some derivatives of DHP showed significant cytotoxicity. It was shown that this effect may not be the result of interaction with Ca(2+) channels. In this study, we performed an investigation about the intrinsic cytotoxicity of some derivatives of DHP containing ...
Miri, Ramin, Javidnia, Katayoun, AmirGhofran, Zahra, Salimi, Seyyed Hossein, Sabetghadam, Zahra, Meili, Savis, Mehdipour, Ahmad Reza   +6 more
openaire   +2 more sources

A Systematic Review on 1, 4-Dihydropyridines and its Analogues: An Elite Scaffold

Biointerface Research in Applied Chemistry, 2021
1,4-Dihydropyridines are a group of pyridine-based molecules possessing a magnificent set of biological and therapeutic potentials. Belonging to the class of calcium channel blockers, they are known to be effective in the conditions, angina, hypertension, myocardial infarction and show vasodilatory and cardiac depressant effects.
openaire   +1 more source

Oxidation of Hantzsch 1,4- Dihydropyridines to Pyridines with Thallium Triacetate [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2003
Hantzsch 1, 4-dihydropyridines (1,4-DHPs) can be oxidized to the corresponding pyridine derivatives by thallium triacetate in high yields.
Mohammad Mahmoodi Hashemi, Mohammad Sadegh Zakeri, Saeed Arianfar   +2 more
doaj  

Catalytic Asymmetric Synthesis of Both Enantiomers of 4‑Substituted 1,4-Dihydropyridines with the Use of Bifunctional Thiourea-Ammonium Salts Bearing Different Counterions

Molecules, 2010
Organoammonium salts composed of a Brønsted acid and an anilinothiourea promoted the Michael addition of β-keto esters and α,β-unsaturated aldehydes in the presence of primary amines to give functionalized 1,4-dihydropyridines enantioselectively.
Kohzo Yoshida, Tsubasa Inokuma, Kiyosei Takasu, Yoshiji Takemoto   +3 more
doaj   +1 more source