Results 111 to 120 of about 85,474,312 (231)

De Novo Synthesis of 1,4-Dihydropyridines and Pyridines

, 2016
An efficient and general method for the synthesis of 1,4-dihydropyridines and pyridines based on a lithiation/isomerization/intramolecular carbolithiation sequence is reported. This procedure provides an efficient, divergent, and straightforward entry to
Gwilherm Evano (1355874), François Couty (1819657), Wafa Gati (1944688), Mohamed B. Rammah (1819654), Mohamed M. Rammah (1819666)   +4 more
core   +1 more source

A QUANTUM CHEMICAL STUDY OF STRUCTURE -ACTIVITY RELATIONSHIPS OF DIHYDROPYRIDINE CALCIUM ANTAGONISTS [PDF]

Journal of Sciences, Islamic Republic of Iran, 1990
Quantum chemical (MNDo)caleulations have beenused toelucidate the molecular properties and structure - activity relationships of dihydropyridine (DHP) type calcium antagonists.
doaj  

De Novo Synthesis of 1,4-Dihydropyridines and Pyridines

, 2012
An efficient and general method for the synthesis of 1,4-dihydropyridines and pyridines based on a lithiation/isomerization/intramolecular carbolithiation sequence is reported. This procedure provides an efficient, divergent, and straightforward entry to
Rammah, B. Mohamed, Rammah, M. Mohamed, Couty, François, Evano, Gwilherm, gati, Wafa   +4 more
core   +1 more source

Peroxynitric Acid: A Convenient Oxygen Source for Oxidation of Organic Compounds Catalyzed by Polyimide-Supported Manganese (III) Tetrakis(4-methoxylphenyl)porphyrin Acetate [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2017
In this work, a polyimide (PI) containing triazole units was synthesized using 3,5-diamino-1,2,4-triazole and pyromellitic dianhydride in N-methyl-2-pyrrolidinone.
Gholamreza Karimipour, Zahra Rafiee, Massomeh Bahramian   +2 more
doaj  

Synthesis and NMR spectroscopic properties of some methyl-substituted 1-methyl-1,4-dihydropyridines

, 1980
The synthesis and NMR spectroscopic properties of some methyl-substituted 1-methyl-1,4-dihydropyridines are ...
de Bie, M. J. A., Bie, M.J.A. de, Budzelaar, P.H.M., Koning, A.J. de, de Koning, A. J., Budzelaar, P. H. M., Boersma, J., Brandsma, L.   +7 more
core   +1 more source

Construction of 3,5-dinitrated 1,4-dihydropyridines modifiable at 1,4-positions by a reaction of β-formyl-β-nitroenamines with aldehydes [PDF]

A novel and efficient method for the synthesis of 4-substituted 3,5-dinitro-1,4-dihydropyridines by a reaction of β-formyl-β-nitroenamines with aldehydes was developed.
Nishiwaki, Nagatoshi, Hamada, Mai, Nakaike, Yumi, Asahara, Haruyasu   +3 more
core  

Copper Catalyst-Promoted Regioselective Multicomponent Cascade Cyclization of 3‑Aza-1,5-enynes with Sulfur Dioxide and Cycloketone Oxime Esters to Access Cyanoalkylsulfonylated 1,2-Dihydropyridines

Radical cascade cyclization via the cracking of alkenyl C–H has emerged as an attractive and remarkable tool for the rapid construction of ring frameworks with endocyclic double bonds.
Le Yang (345935), Tao Ma (88669), Dong Gang (17828427), Yue-Yuan Mao (17828430), Ran Ding (396326), Bing Zhang (129), Hui Gao (169623)   +6 more
core   +1 more source

1,4-Dihydropyridines: Reactivity of nitrosoaryl and nitroaryl derivatives with alkylperoxyl radicals and ABTS radical cation [PDF]

, 2004
In the present paper, a direct quenching of radical species by a number of synthesized nitrosoaryl 1,4-dihydropyridines and their parent nitroaryl 1,4-dihydropyridines was determined in aqueous media at pH 7.4. These two series of compounds were compared
Squella Serrano, Juan, López Alarcón, Camilo, Núñez Vergara, Luis, Valenzuela, V., Camargo Grandón, Rodrigo, Santander, P.   +5 more
core  

Establishing the Thermodynamic Cards of Dipine Models’ Oxidative Metabolism on 21 Potential Elementary Steps

Molecules
Dipines are a type of important antihypertensive drug as L-calcium channel blockers, whose core skeleton is the 1,4-dihydropyridine structure. Since the dihydropyridine ring is a key structural factor for biological activity, the thermodynamics of the ...
Guang-Bin Shen, Shun-Hang Gao, Yan-Wei Jia, Xiao-Qing Zhu, Bao-Chen Qian   +4 more
doaj   +1 more source

Computational Screening of Heterocyclic L-Type Calcium Channel Blockers for Potential Anti-Parkinson’s Activity

Journal of Pharmaceutical Research
Treating cardiovascular disorders like hypertension, arrhythmias, angina pectoris, and congestive heart failure involves using calcium channel blockers that bind allosterically to Cave L-type channels in myocytes in cardiac muscle.
Thomas Kurian, Rani Sebastian
doaj   +1 more source