Results 251 to 260 of about 5,843 (268)

ChemInform Abstract: Synthesis, Properties, and Cardiovascular Activity of Substituted 4‐Dihydropyridine‐2(3H)‐thiones.

ChemInform, 1988
AbstractThe dihydropyridinethiolates (V), prepared by common cyclization reactions, are converted to the thiones (VIII), the betaines (IX), and the sodium salts (X).
A. A. KRAUZE, R. O. VITOLIN'A, M. R. ROMANOVA, G. YA. DUBUR   +3 more
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Electrochemical reduction of 1, 4-dihydropyridine-3, 5-dicarboxylic acid derivatives in an aprotic medium

Chemistry of Heterocyclic Compounds, 1978
The polarographic reduction of 1, 4-dihydropyridine-3, 5-dicarboxylic acid derivatives in dimethylformamide was studied. It is shown that the first diffusion waves of these compounds are irreversible one-electron waves and correspond to electrical reduction of the C=C bond of the conjugated system of the 1, 4-dihydropyridine ring to give a tetrahydro ...
V. P. Kadysh, G. Ya. Dubur, Ya. P. Stradyn, Ya. R. Uldrikis   +3 more
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Topochemical investigations of dimerizing 4-aryl-1, 4-dihydropyridines by X-ray crystal structure analysis

Journal of Molecular Structure, 1999
Abstract X-ray crystal structures of dimerizing 4-aryl-1,4-dihydropyridines and their solid-state irradiation products, either antidimers or cage dimers, were determined to investigate their topochemistry. The products of the solid-state reactions prove to be geometrically defined by the crystal packing of the monomers.
A. Hilgeroth, U. Baumeister, F.W. Heinemann   +2 more
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Aromatization of 1, 4-dihydropyridine derivatives

2006
Pripravljeno je ukupno 29 različito supstituiranih 1, 4-dihidropiridinskih derivata korištenjem nekoliko varijanti Hantzschove kondenzacije. Prilikom pokušaja priprave derivata 35 sa prisutnom metoksi skupinom u ortho-položaju arilne grupe, korištenjem Hantzschove metode sa dva mola aminokrotonatnog estera, izoliran je literaturno novi spoj 49 kao ...
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Enantioselective analysis of 1, 4-dihydropyridine drugs by luquid chromatography

2004
The analyses for the following substances were performed: isradipine, nitrendipine, nicardipine, nisoldipine and felodipine. The most successful separations for the all investigated compounds were achieved on Chiralpak AD column that consist of amylose tris(3, 5-dimethylphenylcarbamat) as chiral selector.
Kalčić, Igor, Vinković, Vladimir, Litvić, Mladen   +2 more
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Enantioselective and diastereoselective preparation of 1, 4-dihydropyridines

2004
Ispitane su različite metode za pripravu enantiomerno čistih 1, 4-dihidropiridinskih spojeva (1, 4-DHP). Rezultati pokazuju da se ovaj tip spojeva dobiva vrlo teško u enantiomerno čistom obliku i da ne postoji jedna općenita metoda za njihovu pripravu.
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Exploring 1, 4-Dihydropyridines: Synthesis, Biological Activities, Therapeutic Potentials and Computational Studies

Abstract: 1, 4-dihydropyridines and their derivatives are the foremost notable class of Nitrogen-containing heterocyclic scaffolds and have been extensively used since they are occupying the highest position in the pharmaceutical industry because of its wider range of biological and medicinal uses.
Sodah, Karun, Khilnani, Dr. Veena, Sharma, Prerna   +2 more
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Synthesis and Biological Evaluation of New 1, 4-Dihydropyridines as Antihypertensives Agents in Rats

2003
New analogues of nifedipine, as a known calcium channel blocker, were synthesized by replacing the orthonitrophenyl group on position 4 with 1-(4-Nitrobenzyl)-5-imidazolyl or 2methylthio-1-(4-Nitrobenzyl)-5-imidazolyl substituent. Effects of the new synthesized compounds on blood pressure were studied at 15, 30 and 60 min after administration by ...
Jorjani, M, Rastegar, H, Roshanzamir, F, Varmazyari, M, Abdollahi, M, Zarghi, Afshin   +5 more
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Synthese de diacyl-1,4 alcoyl-4 dihydropyridines

Tetrahedron Letters, 1969
P.M. Atlani, J.F. Biellmann
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Synthesis and pharmacological activity of 4-aryl-l,4-dihydropyridines

Pharmaceutical Chemistry Journal, 1982
V. V. Kastron, G. Ya. Dubur, R. O. Vitolin', A. A. Kimenis, M. Ya. Selga, N. V. Kondratenko, L. M. Yagupol'skii, D. Ya. Tirzite, Yu. A. Fialkov, S. V. Shelezhenko   +9 more
openaire   +1 more source