Results 251 to 260 of about 11,638,573 (298)
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Unraveling the crystal structure, stability and drug likeness of 1,3,4-oxadiazole derivatives against Myelofibrosis: a combined experimental and computational investigation

Journal of Biomolecular Structure and Dynamics
Herein, we report the synthesis and characterization of novel 1,3,4-oxadiazole derivatives, 2-methoxybenzyl 5-(4-chlorophenyl)-1,3,4-oxadiazole-2-carboxylate (C1) 2-methoxybenzyl 5-(2-chlorophenyl)-1,3,4-oxadiazole-2-carboxylate (C2), and methoxybenzyl 5-
Lohith Tumakuru Nagarajappa   +8 more
semanticscholar   +1 more source

Synthesis and study of poly (1, 3, 4-oxadiazoles)

Chemistry of Heterocyclic Compounds, 1967
Various conditions for synthesizing poly (1,3,4-oxadiazoles) from carboxylic acids, their hydrazides, and polyhydrazides, are investigated. Methods of cyclodehydration of polyhydrazides using phosphorus oxychloride, sulfuric acid, and certain other reagents are not of general utility for synthesizing poly (1,3,4-oxadiazoles).
A. P. Grekov   +2 more
openaire   +1 more source

Design, Synthesis, and Biological Evaluation of 2‐(2‐Bromo‐3‐nitrophenyl)‐5‐phenyl‐1,3,4‐oxadiazole Derivatives as Possible Anti‐Breast Cancer Agents

Chemistry and Biodiversity, 2020
Breast Cancer (BCa) is the most often diagnosed cancer among women who were in the late 1940’s. Breast cancer growth is largely dependent on the expression of estrogen and progesterone receptor.
Arjun H. Ananth   +7 more
semanticscholar   +1 more source

Poly(1, 3, 4-Oxadiazole-Amide)s Containing Pendent Phenoxy Groups

High Performance Polymers, 1996
A series of new poly(1, 3, 4-oxadiazole-amide)s have been synthesized by solution polycondensation of aromatic diamines containing preformed 1, 3, 4-oxadiazole rings with phenoxyterephthalic diacid chloride or by the reaction of the same diacid chloride with p-aminobenzhydrazide resulting in a polyhydrazide-amide which was cyclodehydrated to the ...
Corneliu Hamciuc   +2 more
openaire   +1 more source

SYNTHESIS AND ANTIMICROBIAL ACTIVITIES OF SOME NEW 1, 3, 4-OXADIAZOLES

INDIAN DRUGS, 2012
Various 5-β-[(N-Benzenesulphonyl/tosyl)-4-(un) substituted anilino] ethyl-2-H/CH3/C6H5/-CH2C6H5/p-NO2C6H4-1,3,4-oxadiazoles (5a-d), 5--β-[(N-Benzenesulphonyl/tosyl)-4-(un)-substituted anilino] ethyl-2-(N,N-diethylamino/anilino/morpholino)-1, 3, 4-oxadiazoles (6a-r), 3--β-[(N-Benzenesulphonyl/tosyl)-4-(un) substituted anilino] ethyl-4-amino-5-mercapto-4(
S Desai, U. Laddi
openaire   +1 more source

Synthesis of Some New 1, 3, 4-Oxadiazole, Pyrazole, and Pyrimidine Bearing Thienopyrazole Moieties

Current Organic Synthesis, 2020
Aim and Objective: According to the literature survey, pyrazole is a unique template that is associated with several biological activities. This article highlighted the research work of many researchers reported in the literature for synthesis and different pharmacological activities of the pyrazole nucleus.
Mohamed Ahmed Elian Sophy   +1 more
openaire   +2 more sources

1,2,4-Oxadiazole-Bridged Polynitropyrazole Energetic Materials with Enhanced Thermal Stability and Low Sensitivity.

ChemPlusChem, 2019
A family of mono or di(1,2,4-oxadiazole)-bridged polynitropyrazole derivatives with C-nitro/N-nitro functionalities is reported. All compounds were fully characterized by IR, NMR (1 H, 13 C), elemental analysis and differential scanning calorimetry (DSC).
Tingou Yan, G. Cheng, Hongwei Yang
semanticscholar   +1 more source

Recent Advances in 1, 3, 4-Oxadiazole Chemistry

1967
Publisher Summary This chapter introduces the chemistry of the 1,3,4-oxadiazoles. The 1,3,4-oxadiazoles have large number of applications in diverse areas—for example, in drug syntheses, scintillation materials, and the dyestuffs industry. Ring cleavage reactions of the 1,3,4-oxadiazoles have also excited great interest in various fields, because ...
A. Hetzheim, K. Möckel
openaire   +1 more source

Synthesis Of 3-Aryl-5-[Thien-3-Yl Methyl]-1,2, 4-Oxadiazoles

Synthetic Communications, 1999
Abstract A convenient and efficient synthesis of eight new compounds 5a-h is described. The intermediates 4a-h have also been isolated and characterized the with help of spectroscopic data.
R. M. Srivastava   +3 more
openaire   +1 more source

Azo1,3,4-oxadiazole as a Novel Building Block to Design High-Performance Energetic Materials

Crystal Growth & Design, 2019
In this study, the azo1,3,4-oxadiazole energetic fragment was first introduced into the energetic materials using a simple synthetic strategy, yielding two symmetrical covalent compounds 4 and 5.
Qian Wang, Yanli Shao, Ming Lu
semanticscholar   +1 more source

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