Results 61 to 70 of about 5,785 (211)
Gold–Thiopurine and Thioguanine Platforms for Chemotherapy and Photodynamic Therapy
ChemistryEurope, Volume 4, Issue 3, March 2026.Gold(I)–thiopurine complexes bearing chromophores and phosphine or N‐heterocyclic carbene ligands were developed as multimodal chemo‐photodynamic agents. They show good stability, moderate lipophilicity, and tunable photoresponse. 6‐TG enhances dark cytotoxicity, 6‐MP improves phototoxicity, and PPh3/NBD provide the most efficient photoactivation ...
Laura Agulló +3 more
wiley +1 more source
Synthesis of Mono-Substituted and Simmetrically 2, 5-Disubstituted 1, 3, 4-Oxadiazoles
Chemistry Journal of Moldova, 2012 This article is an extended abstract of a communication presented at the Conference Ecological Chemistry 2012.
Z. Ribcovskaia, F. Macaev
openaire +2 more sources
Preliminary structure-activity relationship studies on some novel s-substituted aliphatic analogues of 5-{1-[(4- chlorophenyl) sulfonyl]-3-piperidinyl}-1, 3, 4-oxadiazol-2-yl sulfide [PDF]
, 2016 Purpose: To study the structure-activity relationships of synthetic multifunctional sulfides through evaluation of lipoxygenase and anti-bacterial activities.Methods: S-substituted derivatives of the parent compound 5-(1-(4- chlorophenylsulfonyl ...
Abbasi, M. Athar +5 more
core +2 more sources
MedComm, Volume 7, Issue 3, March 2026.This review focuses on the clinical features, molecular mechanisms, treatment methods, and preventive measures of the VZV, with the aim of providing a theoretical basis for the development of new treatment and prevention methods for HZ. ABSTRACT Varicella zoster virus (VZV) is a ubiquitous human herpesvirus that establishes lifelong latency and causes ...
Lei Peng +8 more
wiley +1 more source
ChemMedChem, Volume 21, Issue 3, 12 February 2026.An enrichment map, developed using principal components analysis (PCA), shows the relative abundance of inhibitors of synthetic hemozoin (β‐hematin) formation in antiplasmodium chemical space. This 2‐dimensional landscape can be mined to unearth new chemotypes for antimalarial drug development.
Jessica L. Thibaud +9 more
wiley +1 more source
Macromolecular Bioscience, Volume 26, Issue 2, February 2026.We have synthesized a new variant of tetrazole methylsulfone (TzMS) precursor as a thiol‐reactive cross‐linking system for homogenous cell encapsulation in star poly(ethylene glycol) with gelation kinetics in minutes time scale. Our strategy entailed introduction of an electron‐withdrawing substituent at p‐position of the TzMS ring to fine tune the ...
Hafiz Syed Usama Bin Farrukh +5 more
wiley +1 more source
Synthesis and antimicrobial evaluation of some 2,5 disubstituted 1,3,4-oxadiazole derivatives
Research in Pharmaceutical Sciences, 2017 1,3,4-oxadiazoles are interesting compounds because of their valuable biological effects such as cytotoxic, antibacterial, antifungal, and anti-tubercular activities.
Elham Jafari +3 more
doaj +1 more source
Propellants, Explosives, Pyrotechnics, Volume 51, Issue 2, Page 269-276, February 2026.ABSTRACT We examine the new energetic plasticizer 3‐(2‐(2‐(2‐azidoethoxy)ethoxy)ethoxy)‐4‐nitro‐1,2,5‐oxadiazole (NFPEG3N3), three reference compounds (BDNPA/F, Bu‐NENA, and DNDA‐57), and a plasticizer‐free control in a fixed HMX/GAP composite. NFPEG3N3 provides the strongest low‐temperature properties, yielding the lowest formulation glass transition ...
Patrick Lieber +2 more
wiley +1 more source
Medical Laboratory Journal, 2021 Background and objectives: Antibiotic resistance is a major public health challenge. The pervasive antibiotic misuse can lead to increased antibiotic resistance.
Nakisa Zarrabi Ahrabi +2 more
doaj
Tổng hợp và đánh giá hoạt tính kháng khuẩn của một số dẫn xuất naphthalene-1,3,4-oxadiazole
Tạp chí Khoa học Đại học Cần Thơ, 2018 1,3,4-Oxadiazole có nhiều hoạt tính sinh học bao gồm kháng khuẩn, kháng nấm, kháng viêm, giảm đau, hạ lipid máu, kháng ung thư, chống co giật, chống đái tháo đường, kháng virus và chống loét.
Nguyễn Thị Cẩm Hồng +7 more
doaj +1 more source