Results 181 to 190 of about 9,297,922 (227)

An Overview: 1, 3, 4- oxadiazole and its uses

Asian Journal of Research in Chemistry, 2021
Heterocyclic compounds show various potent biological activity. Every heterocyclic compound has different structure, different functional group and designed for different biological activities. Oxadiazole is one of those heterocyclic compounds possess various biological activity. The structure is simple contain carbon, nitrogen, oxygen, hydrogen.
Anuja S. Patil., Shrinivas K. Mohite
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Synthesis of 1, 3, 4-Oxadiazole

Asian Journal of Research in Chemistry, 2017
Synthesis of 1, 3, 4-oxadiazole by the reaction of 2-propyl Benzo imidiazol-2-yl carbohydrazide and 1, 3, dihydro iso indo-2-yl acetic acid (Phthalyl Amino Acids) in presence of HCl and phosphoryl chloride. All the newly synthesized compounds were screened antibacterial activity which shows moderate to mild activity, and yield of the synthesized ...
Maqdoom Farooqui, Syed Nazimuddin
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[1, 2, 4]-Oxadiazoles: Synthesis and Biological Applications

Mini-Reviews in Medicinal Chemistry, 2014
In the present article synthesis and medicinal applications of [1, 2, 4] oxadiazoles are reviewed. The oxadiazoles have a wide range of applications such as Antitussive, Anti-inflammatory, Anaesthetic, Vasodilator, anthelmintic, antiallergic, antiplatelet effects in vitro, antithrombotic properties in vivo, etc.
Rajesh O, Bora, Bashir, Dar, Vidya, Pradhan, Mazahar, Farooqui   +3 more
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2, 5-Dialkyl-1, 3, 4-oxadiazoles

Chemistry of Heterocyclic Compounds, 1970
A single stage method has been developed for the preparation of 2, 5-dialky-1, 3, 4-oxadiazoles from aliphatic carboxylic acids, by boiling with hydrazine hydrochloride in phosphoryl chloride. A mechanism for the synthesis is suggested. The oxadiazoles are characterized, and the group refractivity of the 1, 3, 4-oxadiazole ring has been determined.
M. S. Skorobogatova, Ya. A. Levin, O. A. Raevskii   +2 more
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Study on 1, 3, 4-Oxadiazole Derivatives as an Antibacterial and Antifungal Agents

2021
In the present investigation a new series of 1, 3, 4-oxadiazoles (3a-j) were synthesized by reacting INH (1) and substituted aromatic acids (2) in presence of POCl3. The new compounds were established on the basis of IR, 1H NMR and Mass spectral data.
B. C. Revanasiddappa, E. V. S. Subrahmanyam   +1 more
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Synthesis and study of poly (1, 3, 4-oxadiazoles)

Chemistry of Heterocyclic Compounds, 1967
Various conditions for synthesizing poly (1,3,4-oxadiazoles) from carboxylic acids, their hydrazides, and polyhydrazides, are investigated. Methods of cyclodehydration of polyhydrazides using phosphorus oxychloride, sulfuric acid, and certain other reagents are not of general utility for synthesizing poly (1,3,4-oxadiazoles).
A. P. Grekov, S. A. Malyutenko, K. A. Kornev   +2 more
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A OVERVIEW ON ANTIMICROBIAL AND ANTI-INFLAMMATORY ACTIVITY OF 1, 3, 4-OXADIAZOLES

INDIAN DRUGS, 2020
1, 3, 4-oxadiazoles first came into the lime light about 80 years ago. With the increasing world population, the number of microbial infections has increased all over. To overcome the continuously spreading harmful microbial infections, the need for newer and newer drugs has increased tremendously.
Satvir Singh, Manpreet Kaur, Divya Bhandari, Mandeep Kaur, Monika Gupta   +4 more
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Recent Advances in 1, 3, 4-Oxadiazole Chemistry

1967
Publisher Summary This chapter introduces the chemistry of the 1,3,4-oxadiazoles. The 1,3,4-oxadiazoles have large number of applications in diverse areas—for example, in drug syntheses, scintillation materials, and the dyestuffs industry. Ring cleavage reactions of the 1,3,4-oxadiazoles have also excited great interest in various fields, because ...
A. Hetzheim, K. Möckel
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SYNTHESIS AND ANTIMICROBIAL ACTIVITIES OF SOME NEW 1, 3, 4-OXADIAZOLES

INDIAN DRUGS, 2012
Various 5-β-[(N-Benzenesulphonyl/tosyl)-4-(un) substituted anilino] ethyl-2-H/CH3/C6H5/-CH2C6H5/p-NO2C6H4-1,3,4-oxadiazoles (5a-d), 5--β-[(N-Benzenesulphonyl/tosyl)-4-(un)-substituted anilino] ethyl-2-(N,N-diethylamino/anilino/morpholino)-1, 3, 4-oxadiazoles (6a-r), 3--β-[(N-Benzenesulphonyl/tosyl)-4-(un) substituted anilino] ethyl-4-amino-5-mercapto-4(
S Desai, U. Laddi
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1, 2, 4-Oxadiazoles

1976
Publisher Summary This chapter focuses on the chemistry of 1,2,4-oxadiazoles and the corresponding reduced derivatives. The chapter discusses the synthesis of 1,2,4-oxadiazoles. Two widely used general methods of synthesizing 1,2,4-oxadiazoles embrace 95% of the practical preparations of these compounds: The conversion of amidoximes by means of ...
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