Electroreductive Intermolecular Coupling of 4‑Quinolones with Benzophenones: Synthesis of 2‑Substituted 4‑Quinolones [PDF]
ACS Omega, 2019 The electroreductive coupling of 1-alkoxycarbonyl-4-quinolones with benzophenones in the presence of trimethylsilyl chloride gave adducts reacted at the 2-position of 4-quinolones as trimethylsilyl ethers. The adducts were transformed to 2-(diarylhydroxymethyl)-4-quinolones.
Naoki Kise +3 more
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Hydrogen Bond Assisted Three-Component Tandem Reactions to Access N-Alkyl-4-Quinolones [PDF]
Molecules, 2023 Hydrogen-bonding catalytic reactions have gained great interest. Herein, a hydrogen-bond-assisted three-component tandem reaction for the efficient synthesis of N-alkyl-4-quinolones is described.
Huanhuan Liu +8 more
doaj +2 more sources
Synthetic approach to 2-alkyl-4-quinolones and 2-alkyl-4-quinolone-3-carboxamides based on common β-keto amide precursors [PDF]
Beilstein Journal of Organic Chemistry, 2023 β-Keto amides were used as convenient precursors to both 2-alkyl-4-quinolones and 2-alkyl-4-quinolone-3-carboxamides. The utility of this approach is demonstrated with the synthesis of fourteen novel and four known quinolone derivatives, including ...
Yordanka Mollova-Sapundzhieva +3 more
doaj +2 more sources
Bacterial Alkyl-4-quinolones: Discovery, Structural Diversity and Biological Properties [PDF]
Molecules, 2020 The alkyl-4-quinolones (AQs) are a class of metabolites produced primarily by members of the Pseudomonas and Burkholderia genera, consisting of a 4-quinolone core substituted by a range of pendant groups, most commonly at the C-2 position. The history of
Muhammad Saalim +2 more
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Effective Synthesis of 4-Quinolones by Reductive Cyclization of 2′-Nitrochalcones Using Formic Acid as a CO Surrogate [PDF]
Molecules, 2023 4-Quinolones are the structural elements of many pharmaceutically active compounds. Although several approaches are known for their synthesis, the introduction of an aryl ring in position 2 is problematic with most of them. The reductive cyclization of o-
Francesco Ferretti +3 more
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Hypervalent Iodine(III)-Promoted C3–H Regioselective Halogenation of 4‑Quinolones under Mild Conditions [PDF]
ACS Omega, 2021 Fang Yang +4 more
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4-Quinolones: smart phones of the microbial world. [PDF]
Chem Rev, 2011 The cellular telephone has revolutionized the way in which humans communicate. Since its invention, this device has evolved into the multifunctional “smart phone”. The smart phone provides us with not only a means of communication but also a useful toolkit for managing our daily lives.
Huse H, Whiteley M.
europepmc +4 more sources
Evaluation of the Activity of 4‑Quinolones against Multi-Life Stages of Plasmodium spp. [PDF]
ACS OmegaYasmin Annunciato +31 more
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Essential Guide of Analysis Methods Applied to Silver Complexes with Antibacterial Quinolones [PDF]
Advanced Pharmaceutical Bulletin, 2018 To describe the chemical structure and characterize physico-chemical properties of organometallic complexes it is necessary to use a complex set of analysis methods. Thus, this review has been compiled as a relevant guide which includes the most commonly
Aura Rusu, Gabriel Hancu, Silvia Imre
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1-Phenyl-2-trifluoromethyl-4-quinolone [PDF]
Acta Crystallographica Section E Structure Reports Online, 2007 In the title mol-ecule, C(16)H(10)F(3)NO, the N-bound phenyl ring is oriented nearly orthogonal to the quinolinyl ring in order to avoid steric clashes with the trifluoro-methyl substituent [dihedral angle 89.7 (1)°].
Sadr, Moayad Hossaini +3 more
openaire +4 more sources