Results 1 to 10 of about 2,160 (144)

Electroreductive Intermolecular Coupling of 4‑Quinolones with Benzophenones: Synthesis of 2‑Substituted 4‑Quinolones [PDF]

open access: yesACS Omega, 2019
The electroreductive coupling of 1-alkoxycarbonyl-4-quinolones with benzophenones in the presence of trimethylsilyl chloride gave adducts reacted at the 2-position of 4-quinolones as trimethylsilyl ethers. The adducts were transformed to 2-(diarylhydroxymethyl)-4-quinolones.
Naoki Kise   +3 more
doaj   +4 more sources

Novel Synthesis of 1,2-Substituted 4-Quinolones [PDF]

open access: yesSynOpen, 2018
An efficient method for the straightforward synthesis of N-functionalized 4-quinolones and 1,2-substituted 4-quinolones from simple 2-aminoacetophenones has been developed.
Sreenivasulareddy Bandatmakuru   +1 more
doaj   +3 more sources

Essential Guide of Analysis Methods Applied to Silver Complexes with Antibacterial Quinolones [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2018
To describe the chemical structure and characterize physico-chemical properties of organometallic complexes it is necessary to use a complex set of analysis methods. Thus, this review has been compiled as a relevant guide which includes the most commonly
Aura Rusu, Gabriel Hancu, Silvia Imre
doaj   +1 more source

Hydrogen Bond Assisted Three-Component Tandem Reactions to Access N-Alkyl-4-Quinolones

open access: yesMolecules, 2023
Hydrogen-bonding catalytic reactions have gained great interest. Herein, a hydrogen-bond-assisted three-component tandem reaction for the efficient synthesis of N-alkyl-4-quinolones is described.
Huanhuan Liu   +8 more
doaj   +1 more source

Synthetic approach to 2-alkyl-4-quinolones and 2-alkyl-4-quinolone-3-carboxamides based on common β-keto amide precursors

open access: yesBeilstein Journal of Organic Chemistry, 2023
β-Keto amides were used as convenient precursors to both 2-alkyl-4-quinolones and 2-alkyl-4-quinolone-3-carboxamides. The utility of this approach is demonstrated with the synthesis of fourteen novel and four known quinolone derivatives, including ...
Yordanka Mollova-Sapundzhieva   +3 more
doaj   +1 more source

Synthesis of Quinolones and Zwitterionic Quinolonate Derivatives with Broad-Spectrum Antibiotic Activity

open access: yesPharmaceuticals, 2022
Quinolones are one of the most extensively used therapeutic families of antibiotics. However, the increase in antibiotic-resistant bacteria has rendered many of the available compounds useless.
Beatriz Suay-García   +5 more
doaj   +1 more source

Creation of 4-Quinolone Thioether and Selenoether Derivatives via Pd-NHC Catalysed Cross-Coupling Reaction

open access: yesSynOpen, 2020
Pd-NHC catalysed direct sulfenylation and selenylation of 3-iodo-4-quinolones has been developed. This protocol provides an alternative route for the construction of ipso-C–S and C–Se bond formation in 4-quinolones under aerobic conditions.
Prasanjit Ghosh, Sajal Das
doaj   +1 more source

Effect of Co-Existing Cations and Anions on the Adsorption of Antibiotics on Iron-Containing Minerals

open access: yesMolecules, 2022
The adsorption of antibiotics on minerals is an important process in their environment behavior. The adsorption behavior of antibiotics on iron-containing minerals and the effect of co-existing cations and anions were studied in this work.
Xiaoyu Guan   +6 more
doaj   +1 more source

Interactions of the 4-quinolones with other antibacterials [PDF]

open access: yesJournal of Medical Microbiology, 1989
The effect of sub-inhibitory concentrations of 16 antibacterials on the bactericidal activity of the 4-quinolones nalidixic acid, ciprofloxacin and ofloxacin against Escherichia coli KL16 in nutrient broth was investigated. Sub-inhibitory concentrations of rifampicin, clindamycin, chloramphenicol, erythromycin or tetracycline antagonised the ...
J. T. Smith, C. S. Lewin
openaire   +3 more sources

The determination of six quinolone drug residues in milk tofu by high-performance liquid chromatography-tandem mass spectrometry

open access: yesZhongguo shipin weisheng zazhi, 2023
ObjectiveTo establish a high-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method for the detection of 6 quinolones residues in milk tofu.MethodsThe milk tofu sample was extracted with 0.1 mmol/L EDTA-Mcllvaine buffer with 0.1 ...
WANG Xueqi   +5 more
doaj   +1 more source

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