Results 121 to 130 of about 32,766 (293)

Identification of 5-(Aryl/Heteroaryl)amino-4-quinolones as Potent Membrane-Disrupting Agents to Combat Antibiotic-Resistant Gram-Positive Bacteria. [PDF]

open access: yesJ Med Chem, 2022
Schultz JR   +14 more
europepmc   +1 more source

Dual Allosteric Effect in Glycine/NMDA Receptor Antagonism: A Comparative QSAR Approach

open access: yesPharmaceuticals, 2010
A comparative Hantzsch type QSAR study was conducted using multiple regression analysis on various sets of quinoxalines, quinoxalin-4-ones, quinazoline-2-carboxylates, 4-hydroxyquinolin-2(1H)-ones, 2-carboxytetrahydroquinolines, phenyl-hydroxy-quinolones,
Vipin B. Gupta, Manish Sharma
doaj   +1 more source

Antibiotic‐Induced Dysbiosis of the Gut Microbiota Shifts Host Tryptophan Metabolism and Increases the Susceptibility of Mice to Pulmonary Infection With Pseudomonas aeruginosa

open access: yesImmunology, EarlyView.
Antibiotic‐induced dysbiosis of the gut microbiota shifts host tryptophan metabolism and impairs the innate immune response during Pseudomonas aeruginosa pulmonary infection. (A) Eubiosis: During eubiosis, the intestinal microbiota metabolises tryptophan into indole metabolites, which keeps tryptophan levels within normal serum concentrations. However,
Camila Bernardo de Brito   +19 more
wiley   +1 more source

REVIEW ON ANTIMICROBIAL POTENTIALS OF QUINOLONE DERIVATIVES [PDF]

open access: yes, 2015
The quinolones are a class of bicyclic molecules, organic chemical structures that are related to the heteroaromatic coal tar isolate quinoline. Quinolone antibacterials are widely used.
Asif, Mohammad
core   +1 more source

Validation and Evaluation of Lateral Flow Tests for the Detection of Antimicrobial Residues on Poultry Feathers

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Persistence of antimicrobial drugs (AMDs) administered to poultry is longer in feathers than in edible tissues. Hence, poultry feathers are a suitable matrix to investigate historical exposure contributing to antimicrobial resistance, since current detection methods are either non‐specific or highly technical and costly.
Sophie Hedges   +5 more
wiley   +1 more source

High resistance to tetracycline and ciprofloxacin in bacteria isolated from poultry farms in Ibadan, Nigeria

open access: yesJournal of Infection in Developing Countries, 2018
Introduction: Resistance to ciprofloxacin and tetracycline is increasing in the food chain especially in E. coli strains and more worrisome will be occurrence of extended-spectrum beta-lactamase (ESBL) producers among ciprofloxacin- and tetracycline ...
Tunmise O. Ayandiran   +4 more
doaj   +1 more source

Evidence for a Role of Extraintestinal Pathogenic Escherichia coli, Enterococcus faecalis and Streptococcus gallolyticus in the Aetiology of Exudative Cloacitis in the Critically Endangered Kākāpō (Strigops habroptilus)

open access: yesMolecular Ecology, EarlyView.
ABSTRACT The kākāpō is a critically endangered flightless parrot which suffers from exudative cloacitis, a debilitating disease resulting in inflammation of the vent margin or cloaca. Despite this disease emerging over 20 years ago, the cause of exudative cloacitis remains elusive.
Rebecca K. French   +13 more
wiley   +1 more source

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