Results 31 to 40 of about 31,395 (235)
Communications Chemistry, 2022 Quinolones can possess desirable antibacterial, antiviral and anticancer properties, rending them important synthetic targets for drug discovery purposes.
Feng-Wei Guo +7 more
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Privileged Chiral Photocatalysts
Angewandte Chemie, EarlyView.Privileged chiral catalysts have transformed asymmetric synthesis, conferring generality to processes that are routinely leveraged in the construction of societally important functional small molecules. This mini‐review is intended to survey the conception and evolution of privileged chiral photocatalyst scaffolds that enable simultaneous orchestration
Emanuel Studer +3 more
wiley +2 more sources
Nonclassical Biological Activities of Quinolone Derivatives
Journal of Pharmacy & Pharmaceutical Sciences, 2011 Quinolones are considered as a big family of multi-faceted drugs; their chemical synthesis is flexible and can be easily adapted to prepare new congeners with rationally devised structures.
Mohsen Daneshtalab, Abeer Ahmed
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Docking studies on novel analogs of quinolones against DNA gyrase of Escherichia coli [PDF]
Journal of Pharmacy & Pharmacognosy Research, 2018 Context: Bacterial resistance to antibiotics is the inevitable consequence of the use of antimicrobial agents. Thus, quinolones are an important class of antibacterials; these agents generally consist of a 1-subtituted-1,4-dihydro-4-oxopyridine-3 ...
Cristian Davila +3 more
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Microwave assisted synthesis of 4-quinolones and N,N′-diarylureas
Green Processing and Synthesis, 2013 4-Quinolinones are an important class of alkaloids, widely used as conventional drugs to treat various infectious diseases. In this study, we report the synthesis of 4-quinolones in one step, under microwave irradiation and with diphenyl ether as a ...
Duarte Patricia D. +2 more
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1,2-Substituted 4-(1H)-Quinolones: Synthesis, Antimalarial and Antitrypanosomal Activities in Vitro
Molecules, 2014 A diverse array of 4-(1H)-quinolone derivatives bearing substituents at positions 1 and 2 were synthesized and evaluated for antiprotozoal activities against Plasmodium falciparum and Trypanosoma brucei rhodesiense, and cytotoxicity against L-6 cells in ...
Abraham Wube +6 more
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Metabolites, 2020 Pseudomonas aeruginosa is a ubiquitous environmental bacterium that causes chronic infections of burn wounds and in the lungs of cystic fibrosis (CF) patients.
Andrew C. Lybbert +4 more
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Occurrence of multi-antibiotics in chicken and egg samples in Hubei
Zhongguo shipin weisheng zazhi, 2022 ObjectiveTo investigate the residues of quinolones，tetracyclines and metronidazole in chicken and egg samples in Hubei from 2016 to 2019.MethodsA total of 373 chicken and 365 egg samples collected from 15 cities in Hubei Province were detected by ultra ...
XIAO Yonghua +4 more
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Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao +6 more
wiley +1 more source
Analytical profiling of mutations in quinolone resistance determining region of gyrA gene among UPEC. [PDF]
PLoS ONE, 2018 Mutations in gyrA are the primary cause of quinolone resistance encountered in gram-negative clinical isolates. The prospect of this work was to analyze the role of gyrA mutations in eliciting high quinolone resistance in uropathogenic E.coli (UPEC ...
Lesley R Varughese +5 more
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