Results 61 to 70 of about 32,766 (293)
The Pan African Medical Journal, 2015 INTRODUCTION: it is estimated that 150 million urinary tract infections (UTIs) occur yearly worldwide, resulting in more than 6 billion dollar in direct healthcare cost.
Emilia Enjema Lyonga +9 more
doaj +1 more source
Studies on the bactericidal activities of the 4-quinolones [PDF]
, 1991 The 4-quinolones act primarily on the A subunit of DNA gyrase coded by the gyrA gene. The nalA mutation in gyrA was found to abolish mechanism B which is the first evidence that mechanism B may reside within gyrase.
Howard, Bernadette Maria Anne
core
Quorum Sensing: suatu Sistem Komunikasi Bakteri Fitopatogen, Peranannya pada Proses Infeksi, dan Peluangnya sebagai Basis Pengembangan Strategi Baru dalam Pengendalian Penyakit Tumbuhan [PDF]
, 2009 Previously, it is thought that bacterium is an autonomous unicellular organism with no capacity for collective behavior. Now the paradigm has changed since there are communication between intercell bacteria.
Hadiwiyono, H. (Hadiwiyono)
core +2 more sources
Interfacing B‐DNA and DNA Mimic Foldamers
Angewandte Chemie International Edition, EarlyView.Helical aromatic oligoamide DNA mimic foldamers that reproduce the shape and charge distribution of duplex B‐DNA have been interfaced with DNA duplexes by means of a new linker that serves both as a DNA hairpin and as an aromatic oligoamide unit. In the resulting chimeric molecules, the linker does not perturb the DNA duplex structure and converts the ...
Manuel Loos +10 more
wiley +1 more source
Bactericidal activity of the new 4-quinolones DU-6859a and DV-7751a [PDF]
, 1995 The bactericidal activity of two new 4-quinolones, DU-6859a and DV-7751a, was investigated against strains of Escherichia coli, Staphylococcus aureus, S. epidermidis, Streptococcus pneumoniae and Enterococcus faecalis.
Morrissey, Ian +3 more
core
Cp*Co(III)‐catalyzed C–H functionalization of bioactive heterocyclic motifs
Bulletin of the Korean Chemical Society, EarlyView.Directed carbon–hydrogen bond functionalization of biologically active scaffolds is attractive as it enables the selective modification of sophisticated structures, enhancing the efficiency of drug development by adopting diverse functional groups. This review summarizes recent advances in cobalt‐catalyzed C–H functionalizations of bioactive motifs ...
Yeongmi Park +3 more
wiley +1 more source
mSphere, 2020 Pseudomonas aeruginosa is an opportunistic human pathogen important to diseases such as cystic fibrosis. P. aeruginosa has multiple quorum-sensing (QS) systems, one of which utilizes the signaling molecule 2-heptyl-3-hydroxy-4-quinolone (Pseudomonas ...
Tianyuan Cao +3 more
doaj +3 more sources
Journal of Saudi Chemical Society, 2017 The reaction of aryne with aza-Morita–Baylis–Hillman (aza-MBH) adducts has been studied. Aryne reacts with aza-MBH adducts through a cascade insertion–cyclization–ene reaction to produce 4-quinolones in 18–44% yields; meanwhile, aza-MBH adducts undergo N-
Li-Li Liu +4 more
doaj +1 more source
CleanMat, EarlyView.Iron‐based catalysts activate peroxymonosulfate (PMS) to generate high‐valent iron‐oxo species for water decontamination and clean water production. The activation efficiency of PMS varies significantly depending on iron catalyst properties, while the generation of reactive high‐valent iron intermediates is governed by catalyst characteristics ...
Junpeng Guo +8 more
wiley +1 more source
Chemical Engineering Transactions, 2016 Numerous studies have shown that a variety of pharmaceuticals such as quinolones have been detected in the vicinity of municipal wastewater discharges and livestock agricultural facilities.
N.V. Madalossi +4 more
doaj +1 more source