Results 51 to 60 of about 3,781 (252)
Reaction strategies for synthesis of imidazole derivatives: a review [PDF]
, 2018 The development of a methodical directional synthesis of complex organic molecules with the aim of obtaining the physiologically active substance with selective action takes a central position in modern synthetic organic chemistry.
Atanasova-Stamova, Sylvia Yordanova +2 more
core +2 more sources
BMC Cancer, 2017 Background Expression and activity of heparanase, an endoglycosidase that cleaves heparan sulfate (HS) side chains of proteoglycans, is associated with progression and poor prognosis of many cancers which makes it an attractive drug target in cancer ...
C. P. Baburajeev +9 more
doaj +1 more source
SYNTHESIS, CHARACTERIZATION AND EVALUATION OF ANTICANCER ACTIVITY OF SOME NEW SCHIFF BASES OF 1, 3, 4-THIADIAZOLE DERIVATIVES [PDF]
, 2015 Objective: N-benzylidene-5-phenyl-1, 3, 4-thiadiazol-2-amine derivatives: Synthesis and anticancer activity.Methods: In the present study five new derivatives of N-benzylidene-5-phenyl-1, 3, 4-thiadiazol-2-amine (Schiff bases containing 1, 3, 4 ...
B, Ashok Kumar +5 more
core
SPECTRAL EVALUATION AND ANTIMICROBIAL ACTIVITY OF SYNTHESIZED 4H-1,4-BENZOTHIAZINES [PDF]
, 2021 Objective: 4H-1,4-Benzothiazines constitute an important class of heterocycles containing 1,4-thiazine ring fused to benzene ring. They are extensively used as tranquilizer, antispasmodic, central nervous system depressant, antiulcer, antibacterial ...
GOYAL, ARUN
core +1 more source
DESIGN, SYNTHESIS AND ANTIFUNGAL EVALUATION OF NOVEL SUBSTITUTED 1, 3, 4-OXADIAZOLES, AND 1, 3, 4-THIADIAZOLES [PDF]
, 2015 Objective: The purpose of this research is to evaluate the antifungal activity of synthesized conjugates of thiophene with 1, 3, 4-oxadiazoles and 1, 3, 4-thiadiazoles using in vitro methods.Methods: The series of (IVa-e) and (Va-e) compounds were ...
Mishra, Pradeep, Upadhyay, Prabhat K
core
Molecules, 2002 3-(2-Furanyl)-4-amino-5-mercapto-1,2,4-triazole (1) was prepared from 2-furoic acid through a multi-step reaction sequence. Compound 1 reacted with aromatic acids in the presence of phosphorus oxychloride to give 3-(2-furanyl)-6-aryl-1,2,4-triazolo[3,4-b]
Zi-Yi Zhang +6 more
doaj +1 more source
Synthesis and Preliminary Antimicrobial Study of 2-Amino-5-Mercapto-1,3,4-Thiadiazole Derivatives
Iraqi Journal of Pharmaceutical Sciences, 2017 Nitrogen heterocycles are of a special interest because they constitute an important class of natural and non natural products, many of which exhibit useful biological activities.Among these nitrogen heterocycles are 1, 3, 4-thiadiazole containing ...
Husam A. Ameen, Ahlam J. Qasir
doaj +3 more sources
E-Journal of Chemistry, 2011 In the present study we report the synthesis and antibacterial activity of a new series 2-(1-methyl-4-nitro-1H-imidazol-5-ylsulfonyl)-1,3,4-thiadiazoles (6a-c).
Bahram Letafat +3 more
doaj +1 more source
Rational Design of Donor‐Acceptor Oligomers for Enhanced Charge Separation
Advanced Physics Research, EarlyView.How can molecular symmetry be broken to maximize photoinduced charge separation? Through first‐principles analysis of 22 DTP‐based donor‐acceptor ternary oligomers, this work establishes that combining architectural asymmetry with site‐selective acceptor fluorination creates an ideal electrostatic landscape for frontier orbital segregation.
Jannik Theile +3 more
wiley +1 more source
Cumhuriyet Science Journal, 2018 1,3,4-Thiadiazoles have a variety of biologicalactivities depending on their substituents. This study aims to investigatethe in vitro antioxidant properties of 1R,2R-1,2-bis- (5- (4-hydroxynaphthalen-1-ylazo) - [1,3,4] thiadiazol-2-yl) -ethane- 1,2-diole
Akif Evren Parlak, Pelin Koparır
doaj +1 more source