Results 51 to 60 of about 2,685 (205)

SYNTHESIS, CHARACTERIZATION AND EVALUATION OF ANTICANCER ACTIVITY OF SOME NEW SCHIFF BASES OF 1, 3, 4-THIADIAZOLE DERIVATIVES [PDF]

, 2015
Objective: N-benzylidene-5-phenyl-1, 3, 4-thiadiazol-2-amine derivatives: Synthesis and anticancer activity.Methods: In the present study five new derivatives of N-benzylidene-5-phenyl-1, 3, 4-thiadiazol-2-amine (Schiff bases containing 1, 3, 4 ...
B, Ashok Kumar, Guria, Tanmoy, Maity, Tapan Kumar, Naskar, Arup, Singh, Jagadish, Singha, Tanushree   +5 more
core  

Reaction strategies for synthesis of imidazole derivatives: a review [PDF]

, 2018
The development of a methodical directional synthesis of complex organic molecules with the aim of obtaining the physiologically active substance with selective action takes a central position in modern synthetic organic chemistry.
Atanasova-Stamova, Sylvia Yordanova, Georgieva, Maya Boyanova, Georgieva, Svetlana Fotkova   +2 more
core   +2 more sources

Design Principles for Next Generation of Small Organic Molecules for Photodynamics Therapy Revealed by Nonadiabatic Molecular Dynamics

Chemistry – A European Journal, EarlyView.
Molecular design reshapes the landscape of excited‐state relaxation. Nonadiabatic dynamics reveal how electronic structure guides population flow between competing pathways beyond static energetic arguments. ABSTRACT Nitrobenzochalcogenadiazole derivatives are emerging candidates for photodynamic therapy (PDT), yet the precise mechanisms governing ...
Vinícius N. da Rocha, Davide Avagliano, Paulo C. Piquini   +2 more
wiley   +1 more source

SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME NEW QUINOLINE DERIVATIVES

Zagazig Journal of Pharmaceutical Sciences, 2012
Two series of novel quinoline derivatives; oxadiazolyl and thiadiazolyl quinolines were prepared and evaluated for their antimicrobial activities. The first series; 5-(2-aryl-6-substituted-4-quinolyl)-1.3,4-oxadiazol-2-amines (Va-g) was synthesized by ...
Lobna Abdel-Aziz , Kamel Metwaly , El-Sayed Lashine , Rania Badawy   +3 more
doaj   +1 more source

Action of 2-Amino-1, 3, 4-thiadiazole in Controlling Plant Diseases

Japanese Journal of Phytopathology, 1971
Properties of 2-amino-1, 3, 4-thiadiazole (ATDA) as rice bacterial leaf blight controlling agent were examined.This compound was effective against the disease as foliar application, and also as root application.As foliar spray, ATDA showed immediate therapeutic effect, and the duration of the effect was fairly short.When applied into paddy water, ATDA ...
Kunito YAKUSHIJI, Osamu WAKAE
openaire   +3 more sources

Modular Donor‐Acceptor Diradicaloids Based on an Electron Deficient N‐Heteroacene Acceptor

Small, EarlyView.
This work presents a modular approach to donor‐acceptor‐donor (D‐A‐D) diradicaloids that show systematic evolution of their energy gaps, singlet‐triplet splittings, and diradical character (y). The correlation of (opto)electronic, spin, and magnetic properties with high‐fidelity theoretical investigations provides clear connections between the degree ...
Tanner L. Smith, Zhendian Zhang, Tanya A. Balandin, Paramasivam Mahalingam, Andrew H. Comstock, Anna M. Österholm, Michael K. Bowman, Molly M. Lockart, Guoxiang Hu, Jason D. Azoulay   +9 more
wiley   +1 more source

Synthesis and properties of some 3-(5-(4-methoxyphenyl)pyrazol-3-yl)-6-R-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazoles

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2022
Pyrazole and 1,2,4-triazole derivatives play an important strategic role in modern medicine and pharmacy. This fact is due to the significant possibilities of chemical modification and significant pharmacological potential among the derivatives of ...
S. O. Fedotov, A. S. Hotsulia, O. I. Panasenko   +2 more
doaj   +1 more source

DESIGN, SYNTHESIS AND ANTIFUNGAL EVALUATION OF NOVEL SUBSTITUTED 1, 3, 4-OXADIAZOLES, AND 1, 3, 4-THIADIAZOLES [PDF]

, 2015
Objective: The purpose of this research is to evaluate the antifungal activity of synthesized conjugates of thiophene with 1, 3, 4-oxadiazoles and 1, 3, 4-thiadiazoles using in vitro methods.Methods: The series of (IVa-e) and (Va-e) compounds were ...
Mishra, Pradeep, Upadhyay, Prabhat K
core  

Fluorescent Supramolecular Gels Based on D‐Sorbitol Derivatives

Small, EarlyView.
Sugar‐based fluorescent low‐molecular‐weight gelators (LMWGs) DNapS, DBTDS, and MCumS, prepared by a green, scalable route, form supramolecular gels in water, organic, and deep eutectic solvents. MCumS yields solvent‐dependent nanofibrous networks and viscoelastic injectable eutectogels.
Emmanuel Odella, Miryam Criado‐Gonzalez, Rodrigo A. Ponzio, David Mecerreyes, Matías L. Picchio, Daniele Mantione   +5 more
wiley   +1 more source

Synthesis and Biological Activity of 3-(2-Furanyl)-6-Aryl-1,2,4-Triazolo[3,4-b]-1,3,4 –Thiadiazoles

Molecules, 2002
3-(2-Furanyl)-4-amino-5-mercapto-1,2,4-triazole (1) was prepared from 2-furoic acid through a multi-step reaction sequence. Compound 1 reacted with aromatic acids in the presence of phosphorus oxychloride to give 3-(2-furanyl)-6-aryl-1,2,4-triazolo[3,4-b]
Zi-Yi Zhang, Dong-Yong Chen, Xiang-Yun Nan, Xin-Xiang Lei, Xian-Xing Chen, An-Jiang Zhang, Li-Xue Zhang   +6 more
doaj   +1 more source