Results 111 to 120 of about 762 (252)

A REVIEW: THIAZINES DERIVATIVES TREATED AS POTENTIAL ANTIMICROBIAL AGENTS [PDF]

, 2017
In recent days, heterocycles and their derivatives have become strong reflection in medicinal research and pharmaceutical fields because of their practical pharmacological and biological activities.
Makkar, Reena, Sharma, Praveen Kumar
core   +1 more source

Synthesis, physical-chemical properties and research of acute toxicity of 1,2,4-triazole derivatives containing thiophene core

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2015
The aim of research. Modern drugs must have certain characteristics, such as low toxicity and high efficiency. Special attention should be given to esthers of 2-(1,2,4-triazoles-3-iltio)acetic acids.
V. A. Salionov
doaj   +1 more source

SYNTHESIS AND CHARACTERIZATION OF 4- AMINO-3-MERCAPTO-5-METHYL-1, 2, 4 -TRIAZOLE AND ITS MIXED- LIGANDS COMPLEX WITH Cd (II) IONS [PDF]

In the present investigation, the Schiff base (E)-4-(2-hydroxynaphthalen-1-yl) methylene) amino)-5-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione was prepared by the condensation reaction of 2-hydroxyl-1-naphthaldehyde with  4-amino-3-mercapto-5-methyl-1,
Anweting, Idongesit Bassey, Eno, Ededet Akpan, Johnson, Atim Sunday, Nkom, Nsikanabasi Ekerete   +3 more
core   +1 more source

CREATION, PHYSICAL AND CHEMICAL PROPERTIES OF ALKIL-2-((5-PHENETHYL-4-R-1,2,4- TRIAZOLE-3-YL)THIO)ACET(PROPAN,BENZ)IMIDATES [PDF]

, 2019
Objective: The aim of this research was to synthesize and evaluate physical-chemical properties of 5-pheneyhyl-4-R-3-thio-1,2,4-triazole and to establish identity and structure of the synthesized compounds, namely alkil-2-((5-phenethyl-4-R-1,2,4-triazole-
ANDRIY, KAPLAUSHENKO, ANTONINA, AVRAMENKO, NATALIYA, NAGORNA, TATYANA, IGNATOVA   +3 more
core   +1 more source

Unlocking Catalyst Activation as a Critical Bottleneck in Cross‐Coupling Reactions: Room‐Temperature Couplings of Weak Nucleophiles Enabled by [Pd(1‐MeNAP)TFA]2 Precatalysts

Angewandte Chemie International Edition, EarlyView.
In many Pd‐catalyzed cross‐couplings, catalyst performance has been found to be limited by catalyst activation. Methylnaphthyl (MeNAP) palladium trifluoroacetate dimers are presented as easy‐to‐store and easy‐to‐handle precursors, which rapidly activate under reaction conditions, even when only weakly coordinating, non‐reducing nucleophiles are present.
Sourav Manna, Henric F. Janning, Nikolaos V. Tzouras, Jane Anto Simplica Sagayaraj, Fadil Faizal Mannighayil, Angelino Doppiu, Lukas J. Gooßen   +6 more
wiley   +1 more source

Synthesis and Characterization New 1, 2, 4-Triazole Derivative and Its Complexes with Some Transition Metal Ions [PDF]

An innovative class of ligand compounds using The ions of transition metals (Cr(III), Fe(III), and Ni(II)).The ligand N,N'-(4H-1,2,4-triazole-3,5-diyl)bis(4-methoxybenzamide) was produced by reacting 2,5-di amino-1,2,4-triazole with two moles of methyl 4-
Natheil, Amal Hussein
core   +2 more sources

Azide–alkyne cycloaddition (click) reaction in biomass-derived solvent CyreneTM under one-pot conditions

Beilstein Journal of Organic Chemistry
It was demonstrated that CyreneTM, as a biomass-originated polar aprotic solvent, could be utilized as an alternative reaction medium for one-pot copper(I)-catalyzed azide–alkyne cycloaddition (click or CuAAC) reactions, for the synthesis of various 1,2 ...
Zoltán Medgyesi, László T. Mika
doaj   +1 more source

Comparative Study of Goitrogenic Actions of 3-Substituted 1, 2, 4-Triazoles in Rats.

Journal of Veterinary Medical Science, 1994
Antithyroid actions of 3-amino-1, 2, 4-triazole (ATZ), 3-mercapto-1, 2, 4-triazole (MTZ) and 3-nitro-1, 2, 4-triazole (NTZ), which are substituents on the 3-position of 1, 2, 4-triazole (TZ), and those of the parental compound, were compared in rats. After administration of either ATZ, MTZ, or NTZ, the thyroids of rats were enlarged with decreasing of ...
M, Takaoka, S, Manabe, T, Yamoto, M, Teranishi, N, Matsunuma, H, Masuda, N, Goto   +6 more
openaire   +3 more sources

Geminal Difunctionalization of Ketones via C─S Bond Insertion of Photogenerated Donor–Donor Diazo Compounds

Angewandte Chemie International Edition, EarlyView.
Geminal difunctionalization of readily available building blocks provides rapid access to molecular complexity. This work introduces a strategy for installing two distinct functional groups on a carbonyl carbon by transforming it into a donor–donor diazo compound, enabling both batch and flow applications with broad solvent compatibility.
Vincent George, Aryaman Pattanaik, Daniel Maddox, Lukas M. Sigmund, Giovanna Mejia, Sara Pahlén, Simon O. Angerer, Maria Schmoll, Lisa Marie Schneider, Nidhal Selmi, Mikhail Kabeshov, Giulia Bergonzini, Julia Rehbein, Burkhard König   +13 more
wiley   +1 more source

Synthesis, Characterization and Antimicrobial Activity of Cu(II), Co(II) and Ni(II) Complexes with O, N, and S Donor Ligands

E-Journal of Chemistry, 2008
The complexes of the type ML2 [where M = Cu(II), Co(II), and Ni(II)] L = 1-phenyl-1-ene-3-(2-hydroxyphenyl)-prop-2-ene with 3- substituted-5-mercapto-4-amino-1,2,4-triazoles.
Vidyavati Reddy, Nirdosh Patil, S. D. Angadi   +2 more
doaj   +1 more source