Results 111 to 120 of about 12,877,669 (294)

Synthesis, Characterization and Antimicrobial Properties of Schiff Bases Derived from Condensation of 8-Formyl-7-hydroxy-4-methylcoumarin and Substituted Triazole Derivatives

open access: yesE-Journal of Chemistry, 2009
Two biologically active classes of compounds coumarins and triazoles were employed to form the Schiff bases. The synthesized Schiff base viz., 3-aryl-[(1-isocyano-4-methyl-7-hydroxycoumarin)]-5-methyl-1,3,4-triazoline-2-one and its substituents were ...
Kumar Sanjeev S. Lamani   +3 more
doaj   +1 more source

Mass-spectrometric fragmentation of sodium 2-(4-methyl-5-(thiophene-2-yl)-4H-1,2,4-triazole-3-ylthio)acetate

open access: yesZaporožskij Medicinskij Žurnal, 2015
The study of physical and chemical characteristics and establishing patterns of mass spectrometric fragmentation are the actual tasks of modern pharmaceutical science, have both scientific interest and practical importance. Aim.
V. A. Salionov   +2 more
doaj   +1 more source

[3 + 2] Cycloaddition of Isocyanides with Aryl Diazonium Salts: Catalyst-Dependent Regioselective Synthesis of 1,3- and 1,5-Disubstituted 1,2,4-Triazoles

open access: yes, 2018
An unprecedented catalyst-dependent regioselective [3 + 2] cycloaddition of isocyanides with aryl diazonium salts is reported. 1,3-Disubstituted 1,2,4-triazoles were selectively obtained in high yield under Ag­(I) catalysis, whereas 1,5-disubstituted 1,2,
Xihe Bi   +9 more
core   +1 more source

Synthesis, physical-chemical properties and research of acute toxicity of 1,2,4-triazole derivatives containing thiophene core

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2015
The aim of research. Modern drugs must have certain characteristics, such as low toxicity and high efficiency. Special attention should be given to esthers of 2-(1,2,4-triazoles-3-iltio)acetic acids.
V. A. Salionov
doaj   +1 more source

Click‐Spaltung quartärer Anilinium‐Tetrazine ermöglicht Kaskadenaufbau multifunktioneller biomolekularer Gerüste

open access: yesAngewandte Chemie, EarlyView.
Die Click‐Chemie hat sich von dem Aufbau kovalenter Bindungen hin zum Spalten von Bindungen weiterentwickelt. Hier wird über einen Kaskaden‐Aufbau berichtet, der diese Verfahren kombiniert, um multifunktionale biomolekulare Gerüste in einer modularen Ein‐Topf‐Reaktion aufzubauen.
Markus Staudt   +9 more
wiley   +1 more source

Pd-catalyzed regioselective C-H chlorination of disubstituted 1,2,3-triazoles

open access: yes, 2018
This paper mainly studied Pd-catalyzed regioselective chlorination of disubstituted 1,2,3-triazoles directed by the 1,2,3-triazole ring. A series of regioselective chlorinated products were synthesized in 47–86% yields using Pd(OAc)2 as a catalyst and ...
Qiong Mo (5262569)   +3 more
core   +1 more source

Copper-Catalyzed Decarboxylative Cycloaddition of Propiolic Acids, Azides, and Arylboronic Acids: Construction of Fully Substituted 1,2,3-Triazoles

open access: yes, 2020
A copper-catalyzed decarboxylative cycloaddition of propiolic acids, azides, and arylboronic acids is described. The present reaction provides an efficient and convenient method for the synthesis of various fully substituted 1,2,3-triazoles from readily ...
Ya-Min Li   +13 more
core   +1 more source

Regioselective synthesis of 4-fluoro-1,5-substituted-1,2,3-triazoles from synthetic surrogates of 1-fluoroalkynes [PDF]

open access: yes, 2019
Here, we show that 1-fluoronitroalkenes can serve as synthetic surrogates of 1-fluoroalkynes in [3+2] cycloaddition reactions with organic azides facilitated by a catalytic amount of trifloroacetic acid. This work provides the first regioselective method
Sampad, Jana   +3 more
core   +2 more sources

Mechanistic Evidence for Mild Base-Mediated Intermolecular Trans-Aminoacylations of 1‑Acyl-5-amino‑1H‑1,2,4-triazoles and 5‑Amino‑1H‑1,2,4-triazoles to Afford 5‑Acylamino‑1H‑1,2,4-triazoles

open access: yes
Acylation of 5-amino-1H-1,2,4-triazoles is selective for the nitrogen atom at the ring 1-position of the heterocycle to give 1-acyl-5-amino-1H-1,2,4-triazoles.
Nicholas A. Magnus (1950841)   +3 more
core   +1 more source

Synthesis and Fluorescent Behaviour of 2‑Aryl-4,5-dihydro‑1H‑1,2,4-triazoles

open access: yes, 2016
A series of new 4,5-dihydro-1H-1,2,4-triazoles was synthesized from amidrazones and acetylenedicarboxylic acid esters in the presence of pyridine in toluene.
Olga O. Nesterenko (3564023)   +4 more
core   +1 more source

Home - About - Disclaimer - Privacy