Results 91 to 100 of about 9,324,719 (299)
Angewandte Chemie, EarlyView.Die Kontrolle biologischer Systeme mit organischen Chromophoren hat sich zu einer vielversprechenden Strategie entwickelt und findet Anwendung von der chemischen Biologie bis hin zur Medizin. Die Komplexität von In‐vivo‐Systemen lässt sich jedoch nicht mit nur einer einzigen Lichtwellenlänge adäquat abbilden.
Nadja A. Simeth
wiley +1 more source
Angewandte Chemie, EarlyView.Photochemically generated phosphoryl radicals from iminyl phosphines enable strain‐release addition to azabicyclobutanes, providing access to elusive N‐phosphoryl azetidines. Combined experimental, computational, and EPR studies reveal an unconventional water‐assisted photoredox pathway.
Chandu G. Krishnan +4 more
wiley +2 more sources
Acute toxicity of 5-(furan-2-yl, 2-metylfuran-3-yl)-4-amino-1,2,4-triazole-3-thiol alkyl derivatives
Zaporožskij Medicinskij Žurnal, 2017 The purpose of our work was the further exploration of the new 5-(furan-2-yl, 2-metylfuran-3-yl)-4-amino-1,2,4-triazole-3-thiol alkyl derivatives’ acute toxicity, setting some patterns of alkyl substituents influence by the Sulfur atom on the acute ...
D. M. Danilchenko, V. V. Parchenko
doaj +1 more source
Molecules, 2020 Efficient synthesis of 2,5-diaryl substituted 4-azido-1,2,3-triazoles by the reaction of sodium azide with dichlorosubstituted diazadienes was demonstrated.
Biligma Tsyrenova, Valentine Nenajdenko
doaj +1 more source
Design, Synthesis, Trypanocidal Activity, and Studies on Human Album in Interaction of Novel S-Alkyl-1,2,4-triazoles [PDF]
, 2019 Chagas disease is a neglected tropical disease caused by the hemoflagellated parasite Trypanosoma cruzi (Kinetoplastida). The only available drug to treat chagasic patients in Brazil, the nitroheterocycle benznidazole, is effective solely during the ...
Otávio A. Chaves (5670620) +10 more
core +1 more source
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2014 The creation and improvement of the original domestic medicines is anactual problem of medical and pharmaceutical industries. Chemistry of heterocyclicsystems attracts scientists all over the world, as it is associated with a number of properties of this
R. О. Shcherbyna +3 more
doaj +1 more source
Pd-catalyzed regioselective C-H chlorination of disubstituted 1,2,3-triazoles [PDF]
, 2018 This paper mainly studied Pd-catalyzed regioselective chlorination of disubstituted 1,2,3-triazoles directed by the 1,2,3-triazole ring. A series of regioselective chlorinated products were synthesized in 47–86% yields using Pd(OAc)2 as a catalyst and ...
Qiong Mo (5262569) +3 more
core +1 more source
Mechanistic Evidence for Mild Base-Mediated Intermolecular Trans-Aminoacylations of 1‑Acyl-5-amino‑1H‑1,2,4-triazoles and 5‑Amino‑1H‑1,2,4-triazoles to Afford 5‑Acylamino‑1H‑1,2,4-triazoles [PDF]
Acylation of 5-amino-1H-1,2,4-triazoles is selective for the nitrogen atom at the ring 1-position of the heterocycle to give 1-acyl-5-amino-1H-1,2,4-triazoles.
Nicholas A. Magnus (1950841) +3 more
core +1 more source
Metal-Free Click Synthesis of Functional 1-Substituted-1,2,3-Triazoles [PDF]
, 2019 The 1,2,3-triazole group is one of the most important connective linkers and functional aromatic heterocycles in modern chemistry. The boom in growth of, in particular, 1,4-disubstituted triazole products since the early 2000’s, can be largely attributed
Marie-Claire Giel (7462496) +6 more
core +1 more source
Funktionalisierung von Peptiden auf der festen Phase im späten Synthesestadium
Angewandte Chemie, EarlyView.Peptidmodifikationen sind für die Kontrolle der Eigenschaften von Peptidwirkstoffen von entscheidender Bedeutung. Daher sind Strategien, die einen effizienten und schnellen Einbau nicht‐kanonischer Modifikationen in Peptide in Parallelformaten ermöglichen, sehr gefragt.
Marius Werner +2 more
wiley +1 more source