Results 101 to 110 of about 762 (252)
A REVIEW ON THE VARIOUS BIOLOGICAL ACTIVITIES OF THIADIAZOLE [PDF]
, 2015 Thiadiazole and their derivatives have been studied colossally because of their wide range of biological activity. They are found to be effectual as antibacterial, antimalarial, antiviral, antiinflammatory, anticancer and antianthelminthic agents ...
Mehta, Dinesh, Neetu, Taya, Poonam
core
Synthesis and Characterization of Some New Morpholine Derivatives [PDF]
, 2016 In this paper a new series of morpholine derivatives was prepared by reacting the morpholine with ethyl chloro acetate in the presence triethylamine as a catalyst in benzene gave morpholin-N-ethyl acetate(1) which reacted with hydrazine hydrate in ...
AlKaissi, Sura S. +2 more
core +2 more sources
Angewandte Chemie, EarlyView.Die geminale Difunktionalisierung leicht verfügbarer Bausteine ermöglicht einen schnellen Zugang zu molekularer Komplexität. Diese Arbeit stellt eine Strategie vor, um zwei unterschiedliche funktionelle Gruppen an einem Carbonylkohlenstoff zu installieren, indem dieser in eine Donor–Donor‐Diazo‐Verbindung überführt wird. Die Methode ist sowohl im Batch‐
Vincent George +13 more
wiley +1 more source
ANTIPROLIFERATIVE, ADME AND POTENTIAL IN SILICO G6PDH INHIBITORY ACTIVITY OF NOVEL 2-(1-BENZOFURAN-2-YL)-4-(5-PHENYL-4H-1, 2, 4-TRIAZOL-3-YL) QUINOLINE DERIVATIVES [PDF]
, 2016 Objectives: Synthesis of new 2-(1-benzofuran-2-yl)-4-(5-phenyl-4H-1, 2, 4-triazol-3-yl) quinoline and its derivatives for antiproliferative potential against cancer cells.Methods: The general methods were employed for the synthesis and the structures ...
D., Satyanarayan N. +7 more
core +1 more source
Zaporožskij Medicinskij Žurnal, 2015 The study of physical and chemical characteristics and establishing patterns of mass spectrometric fragmentation are the actual tasks of modern pharmaceutical science, have both scientific interest and practical importance. Aim.
V. A. Salionov +2 more
doaj +1 more source
E-Journal of Chemistry, 2009 Two biologically active classes of compounds coumarins and triazoles were employed to form the Schiff bases. The synthesized Schiff base viz., 3-aryl-[(1-isocyano-4-methyl-7-hydroxycoumarin)]-5-methyl-1,3,4-triazoline-2-one and its substituents were ...
Kumar Sanjeev S. Lamani +3 more
doaj +1 more source
Zaporožskij Medicinskij Žurnal, 2016 The aim of this work was the study of actoprotective activity of compounds, which combine sintons of 1,2,4-triazole-3-thiol and theophylline. Materials and methods.
A. S. Gotsulya
doaj
BMC MicrobiologyPotassium-competitive acid blockers (P-CABs), such as revaprazan (REV), act by competitively inhibiting potassium (K+) binding on the proton pump (H+/K+-ATPase) and are reversible K+ antagonists.
Wenxu Cheng +6 more
doaj +1 more source
The synthesis of potential analgesics derived from thebaine [PDF]
, 1979 The thesis describes the synthesis of novel bridged thebaine derivatives with heterocyclic rings attached to C-7 and a study of the associated chemistry. Use has been made of the α-hydrazide (3) formed from the α-ester (2), itself prepared by Diels-Alder
Michael Burton (4178776)
core
A Synergistic Inhibitor Development Strategy Against Human UDP‐Galactose‐4‐Epimerase
Angewandte Chemie International Edition, EarlyView.The epimerase GalE is crucial for the biosynthesis of cancer‐relevant O‐GalNAc glycans. Here, we employ orthogonal, structurally enabled small molecule fragment screens to yield both covalent and non‐covalent inhibitors against GalE within no more than 22 elaborated compounds.
William M. Browne +22 more
wiley +1 more source