Results 81 to 90 of about 12,877,669 (294)
Angewandte Chemie, EarlyView.Metadynamics simulations drive automated reaction exploration of acid‐catalysed drug degradation, generating a network spanning 1720 species and 2471 elementary steps. QM‐based filtering reduces the network to eight candidate pathways for rigorous DFT refinement and microkinetic modelling.
Julius Seumer +5 more
wiley +2 more sources
, 2022 Significant advances have been achieved for the construction of chiral skeletons containing 1,2,3-triazoles via transition-metal-catalyzed asymmetric azide–alkyne cycloaddition; however, most of them have been limited to terminal alkynes in the synthesis
Long Li +15 more
core +1 more source
Polyproline: A Synthetic Polypeptide With Unique Properties
Angewandte Chemie, EarlyView.Poly‐L‐proline is a unique polypeptide distinguished by its well‐defined secondary structures and unusual thermal behavior. This mini review highlights recent advances in the synthesis of poly‐L‐proline by N‐carboxyanhydride (NCA) polymerization, the formation of structurally defined architectures and nanostructures, and emerging strategies that ...
Rosanna Le Scouarnec +3 more
wiley +2 more sources
Acute toxicity of 5-(furan-2-yl, 2-metylfuran-3-yl)-4-amino-1,2,4-triazole-3-thiol alkyl derivatives
Zaporožskij Medicinskij Žurnal, 2017 The purpose of our work was the further exploration of the new 5-(furan-2-yl, 2-metylfuran-3-yl)-4-amino-1,2,4-triazole-3-thiol alkyl derivatives’ acute toxicity, setting some patterns of alkyl substituents influence by the Sulfur atom on the acute ...
D. M. Danilchenko, V. V. Parchenko
doaj +1 more source
Molecules, 2020 Efficient synthesis of 2,5-diaryl substituted 4-azido-1,2,3-triazoles by the reaction of sodium azide with dichlorosubstituted diazadienes was demonstrated.
Biligma Tsyrenova, Valentine Nenajdenko
doaj +1 more source
Angewandte Chemie, EarlyView.The luminescence of a heterometallic d‐s {Cu2I2Na2} phosphane‐phosphinate aggregate is regulated by an interplay of Na+–π/I– contacts and reversible coordination of oxygen‐containing organic molecules to Na ions. Structural variations caused by the incoming guest lead to a wide and selective variation of the emission color and illustrate a new approach
Henna Korhonen +10 more
wiley +2 more sources
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2014 The creation and improvement of the original domestic medicines is anactual problem of medical and pharmaceutical industries. Chemistry of heterocyclicsystems attracts scientists all over the world, as it is associated with a number of properties of this
R. О. Shcherbyna +3 more
doaj +1 more source
, 2022 We report a copper-catalyzed cycloaddition of hydrogen azide (hydrazoic acid, HN3) with terminal alkynes to form 4-substituted-1H-1,2,3-triazoles in a sustainable manner.
Martin Gazvoda +5 more
core +1 more source
Zaporožskij Medicinskij Žurnal, 2015 Aim. To analyze the carbonyl derivatives of 7-((3-thio-4-R-4H-1,2,4-triazole-5-yl)methyl)theophylline their mother substance was synthesized and its interaction with α-haloketones series was carried out. Methods and results.
A. S. Gotsulia +3 more
doaj +1 more source
Die Aza‐Büchner–Curtius–Schlotterbeck‐Reaktion: Selektive Bildung Quartärer Kohlenstoffzentren
Angewandte Chemie, EarlyView.Wir stellen die Aza‐Büchner–Curtius–Schlotterbeck‐(ABCS)‐Reaktion vor: eine milde, katalysatorfreie Methode zur Homologierung von Aryliminen. Im Gegensatz zum traditionellen BCS‐Mechanismus durchläuft das Diazo‐Intermediat eine selektive C─C‐Insertion zur Bildung eines quartären Zentrums.
Simon O. Angerer +6 more
wiley +1 more source