Results 211 to 220 of about 18,771 (284)

Targeting fungal lipid synthesis for antifungal drug development and potentiation of contemporary antifungals. [PDF]

NPJ Antimicrob Resist
Gutierrez-Perez C, Cramer RA.
europepmc   +1 more source

Research progress of antibody coupling technique in targeted drug delivery

Interdisciplinary Medicine, EarlyView.
Abstract Antibody‐drug conjugates are a cutting‐edge biotechnology recently attracting wide attention in the medical field. Binding antibodies to drug molecules could deliver drugs precisely to the site of the lesion, which shows great potential in the treatment of tumors and immune diseases.
Meng Li, Tiantian Wang, Dan Tan, Mengqi Wang, Changhai Lei, Yuqing Wang, Shi Hu   +6 more
wiley   +1 more source

Clinical aspects and recent advances in fungal diseases impacting human health. [PDF]

J Antimicrob Chemother
Pagano L, Fernández OM.
europepmc   +1 more source

The Development and Challenges of PET/MRI Dual‐Modality Imaging Probes—An Update

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT The integration of Positron emission tomography (PET) with Magnetic resonance imaging (MRI) combines the functional imaging capabilities of PET with the high‐resolution anatomical detail of MRI, creating a synergistic platform for advanced diagnostic imaging and image‐guided therapies. Central to the success of this dual‐modality system is the
Maryam Sabbaghan, Saumya Nigam, Isabella Kasabasic, Medha Manepalli, Ping Wang, Jinda Fan   +5 more
wiley   +1 more source

Synthesis of Functionalized 1<i>H</i>-Imidazoles via Denitrogenative Transformation of 5-Amino-1,2,3-Triazoles. [PDF]

Molecules
Gribanov PS, Philippova AN, Smol'yakov AF, Tukhvatullina DN, Vlasova VA, Topchiy MA, Asachenko AF, Osipov SN.   +7 more
europepmc   +1 more source

Transformation of 5-acylated N-fluoroalkyl-1,2,3-triazoles to trifluoromethylated ring-fused isoquinolines, 1,3-oxazines, and 1,3-oxazin-6-ones via ketenimines. [PDF]

RSC Adv
Janecký L, Klepetářová B, Beier P.
europepmc   +1 more source

Engineering Folic Acid‐Modified Nanoparticles to Enhance Letrozole's Anticancer Action

Macromolecular Bioscience, EarlyView.
Folate‐functionalized, pH‐sensitive nanoparticles (NPs) are developed for the targeted delivery of letrozole (LTZ) in breast cancer therapy. LTZ‐loaded PCL‐co‐PEG NPs exhibit controlled release, enhanced cytotoxicity, and apoptosis induction in MCF‐7 cells.
Neda Rostami, Abuzar Nikzad, Shervin Shaybani, Hadi Noei, Aida Ghebleh, Mehdi Alidadi, Hanie Abbasi, Sidi A. Bencherif   +7 more
wiley   +1 more source

Synthesis and biological evaluation of novel D-ring fused steroidal N(2)-substituted-1,2,3-triazoles. [PDF]

RSC Med Chem
Tenjović B, Bekić S, Ćelić A, Petri E, Scholda J, Kopp F, Sakač M, Nikolić A.   +7 more
europepmc   +1 more source

Self‐Assembly of Noncanonical Peptides: A New Frontier in Cancer Therapeutics and Beyond

Macromolecular Bioscience, EarlyView.
Representative examples of noncanonical peptide assemblies in anticancer therapeutics, biomaterials, regenerative medicine, molecular imaging, and catalysis are discussed, highlighting enzyme‐instructed self‐assembly as a valuable approach for constructing biomimetic and bioinspired materials that bridge the interface between biological systems and ...
Lin Bai, Meihui Yi, Bing Xu
wiley   +1 more source

Profiling the endocrine-disrupting properties of triazines, triazoles, and short-chain PFAS. [PDF]

Toxicol Sci
Carlier MP, Cenijn PH, Baygildiev T, Irwan J, Escher SE, van Duursen MBM, Hamers T.   +6 more
europepmc   +1 more source