An Atypical Dinuclear Copper(II) 1,2,4-Triazolyl Complex as a Catalyst for Palladium-Free Csp-Csp Homocoupling of Phenylacetylene. [PDF]
Luciani L +3 more
europepmc +1 more source
1, 2, 4-Triazole Scafolds : Recent Advances and Pharmacological Applications
Anjali Thakur +4 more
openaire +1 more source
Abstract figure legend Both ATP synthase and adenine nucleotide translocator (ANT) play key roles in mediating the permeability transition. The contribution of ANT becomes evident in the presence of atractylate (ATR) at pH 6.5, a condition that prevents ATP synthase channel activity. At pH 7.4, this effect is minimal, suggesting a critical role for ATP
Ludovica Tommasin +7 more
wiley +1 more source
Nucleophilic substitution of a phthalimidyl group with morpholine in an N<sup>1</sup>-methyl-1,2,3-triazole: crystallographic evidence for migration of the methylene bridge. [PDF]
Palme PR +5 more
europepmc +1 more source
ABSTRACT Poly(ADP‐ribose) polymerase‐1 (PARP‐1) plays a central role in the repair of DNA single‐strand breaks and represents an established therapeutic target in cancer treatment. In this study, a series of novel oxadiazole–morpholine hybrid compounds was designed and synthesized using a structure‐based drug design approach to target the catalytic ...
Nader R. Albujuq +6 more
wiley +1 more source
Mechano-Induced Synthesis of Polyethylene Glycols α,ω-DiSubstituted with 4-(PAH)-1H-1,2,3-Triazoles in Presence of In Situ-Generated Bronze Microparticles as Catalyst. [PDF]
Mohammed MS +6 more
europepmc +1 more source
Abstract BACKGROUND Hospital premises generate wastewater containing a wide spectrum of contaminants, such as pharmaceutically active compounds (PhACs), antibiotic resistance genes (ARGs) and pathogenic microorganisms, whilst plenty of them are classified under the antibiotic resistant bacteria (ΑRΒ) category.
Andreas Kaliakatsos +11 more
wiley +1 more source
Triazoles Versus Echinocandins for the First-Line Treatment of Invasive Pulmonary Aspergillosis: A Propensity Score-Weighted Multicenter Study. [PDF]
Hatzl S +9 more
europepmc +1 more source
This study explores new antifungal strategies to combat non‐albicans Candida species. We tested clinically approved HDAC inhibitors—Vorinostat, Romidepsin, Tucidinostat—and the HDAC6/8‐selective MC1568, alone and with Fluconazole. The Fluconazole/MC1568 combination significantly enhanced antifungal activity and reduced biofilm formation.
Andrea Giammarino +10 more
wiley +1 more source
Structure-Property Correlations in Disubstituted 1,2,3-Triazoles: DFT Insights and Photophysical Analysis. [PDF]
Lakhani D +9 more
europepmc +1 more source

