Results 21 to 30 of about 134,477 (121)
Properties of untranslated regions of the
BMC Genomics, 2009 Background During evolution selection forces such as changing environments shape the architecture of genomes. The distribution of genes along chromosomes and the length of intragenic regions are basic genomic features known to play a major role in the ...
Tuller Tamir +2 more
doaj +2 more sources
The 3' untranslated regions of influenza genomic sequences are 5'PPP-independent ligands for RIG-I. [PDF]
PLoS ONE, 2012 Retinoic acid inducible gene-I (RIG-I) is a key regulator of antiviral immunity. RIG-I is generally thought to be activated by ssRNA species containing a 5'-triphosphate (PPP) group or by unphosphorylated dsRNA up to ~300 bp in length. However, it is not
William G Davis +12 more
doaj +3 more sources
The Roles of Picornavirus Untranslated Regions in Infection and Innate Immunity
Frontiers in Microbiology, 2018 Viral genomes have evolved to maximize their potential of overcoming host defense mechanisms and to induce a variety of disease syndromes. Structurally, a genome of a virus consists of coding and noncoding regions, and both have been shown to contribute ...
Anna Kloc +2 more
doaj +2 more sources
MicroRNA genes and their target 3'-untranslated regions are infrequently somatically mutated in ovarian cancers. [PDF]
PLoS ONE, 2012 MicroRNAs are key regulators of gene expression and have been shown to have altered expression in a variety of cancer types, including epithelial ovarian cancer.
Georgina L Ryland +9 more
doaj +2 more sources
Evidence for widespread translation of 5' untranslated regions. [PDF]
Nucleic Acids ResNational Human Genome Research Institute of the National Institutes of Health [U41 HG007234]; Spanish Ministry of Science, Innovation and Universities [PGC2018- 097019-B-I00]; Carlos III Institute of Health-Fondo de Investigación Sanitaria [IPT17/0019]; ‘
Rodriguez JM +5 more
europepmc +2 more sources
3' untranslated regions: regulation at the end of the road [PDF]
, 2023 Post-transcriptional gene regulation in bacteria plays a major role in the adaptation of bacterial cells to the changing conditions encountered in the environment.
Balsalobre Parra, Carlos +1 more
core +1 more source
Malaria Journal, 2022 Background The eukaryotic parasite Plasmodium falciparum causes millions of malarial infections annually while drug resistance to common anti-malarials is further confounding eradication efforts.
Valentina E. Garcia +2 more
doaj +1 more source
Cell Reports, 2020 Summary: Bacterial pathogens often employ RNA regulatory elements located in the 5′ untranslated regions (UTRs) to control gene expression. Using a comparative structural analysis, we examine the structure of 5′ UTRs at a global scale in the pathogenic ...
Dmitriy Ignatov +10 more
doaj +1 more source
Regulatory 3′ Untranslated Regions of Bacterial mRNAs [PDF]
, 2017 The untranslated regions (UTRs) of mRNA contain important features that are relevant to the post-transcriptional and translational regulation of gene expression.
Yi-Cheng Sun +2 more
core +1 more source
Is there a classical nonsense-mediated decay pathway in trypanosomes? [PDF]
PLoS ONE, 2011 In many eukaryotes, messenger RNAs with premature termination codons are destroyed by a process called "nonsense-mediated decay", which requires the RNA helicase Upf1 and also, usually, an interacting factor, Upf2.
Praveen Delhi +4 more
doaj +1 more source