Oxidative DNA damage modulates genome and epigenome integrity via base excision repair [PDF]
, 2021 Oxidative DNA damage is one of the leading causes of genome instability, cell death, and diseases. It is repaired by DNA base excision repair (BER), during which repair and translesion DNA polymerases may incorporate damaged nucleotides and mediate RNA ...
Tsegay, Pawlos S.
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Biological Evaluation of DNA Biomarkers in a Chemically Defined and Site-Specific Manner [PDF]
, 2019 As described elsewhere in this Special Issue on biomarkers, much progress has been made in the detection of modified DNA within organisms at endogenous and exogenous levels of exposure to chemical species, including putative carcinogens and ...
Bian, Ke +3 more
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DNA Damage, Oxidative Stress and Related Metabolic By-Products in Cancer and Environmental Studies [PDF]
, 2022 Computational fluid dynamics (CFD), which uses numerical analysis to predict and model complex flow behaviors and transport processes, has become a mainstream tool in engineering process research and development.
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Active transcriptomic and proteomic reprogramming in the C-elegans nucleotide excision repair mutant xpa-1 [PDF]
, 2013 Peer ...
Arczewska, Katarzyna D. +16 more
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Bypassing a 8,5'-cyclo-2'-deoxyadenosine lesion by human DNA polymerase η at atomic resolution. [PDF]
Proc Natl Acad Sci U S A, 2018 Weng PJ +5 more
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Chemistry meets biology in colitis-associated carcinogenesis [PDF]
, 2013 The intestine comprises an exceptional venue for a dynamic and complex interplay of numerous chemical and biological processes. Here, multiple chemical and biological systems, including the intestinal tissue itself, its associated immune system, the gut ...
Dedon, Peter C. +4 more
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Novel Antitumoral Strategies Inducing Membrane Lipid and DNA Damage:Artificial Chemical Nucleases & the ‘ClickGene’ Project [PDF]
, 2019 This PhD project was carried out within the frame of a Marie Curie Network with the acronym ‘ClickGene’, which focuses on the development of next-generation gene silencing therapeutics, such as the artificial metallo-nucleases (AMNs).
Menounou, Georgia <1991>
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Towards a circular economy: fabrication and characterization of biodegradable plates from sugarcane waste [PDF]
, 2023 Bagasse pulp is a promising material to produce biodegradable plates. Bagasse is the fibrous residue that remains after sugarcane stalks are crushed to extract their juice.
Irene S. Fahim, Yara Hossam
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Mutagenesis and Genetic Control of Translesion Synthesis Across an Abasic Site, 8,5’-Cyclopurines and \u3cem\u3eO\u3c/em\u3e\u3csup\u3e2\u3c/sup\u3e-Alkylthymidine DNA Lesions [PDF]
, 2015 DNA contains the genetic information of all living organisms. Therefore, its integrity and stability are essential for the long-term viability of the organism.
Weerasooriya, Savithri Anurada Kumari
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Epigenetic Instability Induced by DNA Base Lesion via DNA Base Excision Repair [PDF]
, 2017 DNA damage can cause genome instability, which may lead to human cancer. The most common form of DNA damage is DNA base damage, which is efficiently repaired by DNA base excision repair (BER).
Jiang, Zhongliang
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