Results 41 to 50 of about 345,197 (240)

Regulatory 3′ Untranslated Regions of Bacterial mRNAs [PDF]

, 2017
The untranslated regions (UTRs) of mRNA contain important features that are relevant to the post-transcriptional and translational regulation of gene expression.
Yi-Cheng Sun, Gai-Xian Ren, Xiao-Peng Guo   +2 more
core   +1 more source

Is there a classical nonsense-mediated decay pathway in trypanosomes? [PDF]

PLoS ONE, 2011
In many eukaryotes, messenger RNAs with premature termination codons are destroyed by a process called "nonsense-mediated decay", which requires the RNA helicase Upf1 and also, usually, an interacting factor, Upf2.
Praveen Delhi, Rafael Queiroz, Diana Inchaustegui, Mark Carrington, Christine Clayton   +4 more
doaj   +1 more source

Post-transcriptional control of nuclear-encoded cytochrome oxidase subunits in Trypanosoma brucei:evidence for genome-wide conservation of life-cycle stage-specific regulatory elements [PDF]

, 2006
Trypanosomes represent an excellent model for the post-transcriptional regulation of gene expression because their genome is organized into polycistronic transcription units.
Katelyn Fenn, Matthew Mayho, Keith Matthews, Fenn, Katelyn, Matthews, Keith; id_orcid, Crosthwaite, Susan, Susan Crosthwaite, Craddy, Paul, Mayho, Matthew, Matthews, Keith, Paul Craddy   +10 more
core   +1 more source

Epidemiology of Human Parechovirus Type1 in Clinical Samples from Children with Gastroenteritis Using RT-PCR [PDF]

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2011
Background and Objectives: Human parechovirus type-1 (HPeV-1) is a genus of picornaviridea with a single stranded positive sense RNA genome. In general it seems to be responsible for more gastrointestinal and respiratory syndromes and less responsible ...
F Ghazi, Z Ata’ei, B Dabirmanesh, M Taghizadeh   +3 more
doaj   +1 more source

The 3' untranslated regions of influenza genomic sequences are 5'PPP-independent ligands for RIG-I. [PDF]

PLoS ONE, 2012
Retinoic acid inducible gene-I (RIG-I) is a key regulator of antiviral immunity. RIG-I is generally thought to be activated by ssRNA species containing a 5'-triphosphate (PPP) group or by unphosphorylated dsRNA up to ~300 bp in length. However, it is not
William G Davis, J Bradford Bowzard, Suresh D Sharma, Mayim E Wiens, Priya Ranjan, Shivaprakash Gangappa, Olga Stuchlik, Jan Pohl, Ruben O Donis, Jacqueline M Katz, Craig E Cameron, Takashi Fujita, Suryaprakash Sambhara   +12 more
doaj   +1 more source

RNA-Protein Interaction Analysis of SARS-CoV-2 5′ and 3′ Untranslated Regions Reveals a Role of Lysosome-Associated Membrane Protein-2a during Viral Infection

mSystems, 2021
Replication of a positive-strand RNA virus involves an RNA-protein complex consisting of viral genomic RNA, host RNA(s), virus-encoded proteins, and host proteins.
Rohit Verma, Sandhini Saha, Shiv Kumar, Shailendra Mani, Tushar Kanti Maiti, Milan Surjit   +5 more
doaj   +3 more sources

Tunable protein synthesis by transcript isoforms in human cells

eLife, 2016
Eukaryotic genes generate multiple RNA transcript isoforms though alternative transcription, splicing, and polyadenylation. However, the relationship between human transcript diversity and protein production is complex as each isoform can be translated ...
Stephen N Floor, Jennifer A Doudna
doaj   +1 more source

The 5′ and 3′ Untranslated Regions of the Japanese Encephalitis Virus (JEV): Molecular Genetics and Higher Order Structures

Frontiers in Microbiology, 2021
The untranslated region (UTRs) of viral genome are important for viral replication and immune modulation. Japanese encephalitis virus (JEV) is the most significant cause of epidemic encephalitis worldwide.
Hong Liu, Hong Liu, Jun Zhang, Yuzhen Niu, Guodong Liang   +4 more
doaj   +1 more source

Improving plant transient expression through the rational design of synthetic 5′ and 3′ untranslated regions

Plant Methods, 2019
Background The growing field of plant molecular farming relies on expression vectors that allow high yields of recombinant proteins to be produced through transient gene expression.
Hadrien Peyret, James K. M. Brown, George P. Lomonossoff   +2 more
doaj   +1 more source

Regulation of translation in haloarchaea: 5'- and 3'-UTRs are essential and have to functionally interact in vivo

, 2009
Recently a first genome-wide analysis of translational regulation using prokaryotic species had been performed which revealed that regulation of translational efficiency plays an important role in haloarchaea.
Jörg Soppa, Brenneis, Mariam, Mariam Brenneis, Soppa, Jörg (Prof. Dr.), Brenneis Mariam, Soppa Jörg   +5 more
core   +1 more source