Results 31 to 40 of about 345,197 (240)

Post-transcriptional control ofPseudomonas aeruginosa lasBexpression involves the 5′ untranslated region of the mRNA [PDF]

open access: yesFEMS Microbiology Letters, 1998
To investigate the regulatory role of the 5' untranslated region of Pseudomonas aeruginosa lasB mRNA, several lasB-lacZ protein and operon fusions were generated. By examining expression of these fusions in strain PAO1 we showed that the 5' untranslated leader sequence was involved in the post-transcriptional iron regulation of elastase. Two components
M J, Brumlik, D G, Storey
openaire   +2 more sources

3' untranslated regions: regulation at the end of the road [PDF]

open access: yes, 2023
Post-transcriptional gene regulation in bacteria plays a major role in the adaptation of bacterial cells to the changing conditions encountered in the environment.
Balsalobre Parra, Carlos   +1 more
core   +1 more source

SMAD4–201 transcript as a putative biomarker in colorectal cancer

open access: yesBMC Cancer, 2022
Background Transcripts with alternative 5′-untranslated regions (UTRs) result from the activity of alternative promoters and they can determine gene expression by influencing its stability and translational efficiency, thus executing complex regulation ...
Tamara Babic   +4 more
doaj   +1 more source

Regulatory components at thecsgDpromoter – additional roles for OmpR and integration host factor and role of the 5′ untranslated region [PDF]

open access: yesFEMS Microbiology Letters, 2006
CsgD is a master regulator of multicellular behaviour in Salmonella enterica serovar Typhimurium. Expression of CsgD is highly regulated on the transcriptional level. A nucleo-protein complex had been defined where the global regulators OmpR and integration host factor (IHF) bind up- and downstream of the csgD core promoter.
Ulrich, Gerstel   +2 more
openaire   +2 more sources

High-Resolution Mapping of Transcription Initiation in the Asexual Stages of Toxoplasma gondii

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Toxoplasma gondii is a common parasite of humans and animals, causing life-threatening disease in the immunocompromized, fetal abnormalities when contracted during gestation, and recurrent ocular lesions in some patients.
Benedikt M. Markus   +6 more
doaj   +1 more source

DETECTING PATTERNS IN 5’ UNTRANSLATED REGIONS OF GENES INVOLVED IN THE REGULATION OF BLOOD PRESSURE AND OXIDATIVE STRESS [PDF]

open access: yesAmerican Medical Journal, 2013
Hypertension is a chronic physical condition with multifactorial causes. Although genetic factors have been associated to this pathological condition, characterization of the sequence patterns in the regulatory sites, for example, in 3’ or 5’ Untranslated Regions (UTR), remains to be explored.
openaire   +1 more source

5’ and 3’ untranslated regions strongly enhance performance of geminiviral replicons in Nicotiana benthamiana leaves

open access: yesFrontiers in Plant Science, 2016
We previously reported a recombinant protein production system based on a geminivirus replicon that yields high levels of vaccine antigens and monoclonal antibodies in plants.
Andrew G. Diamos   +2 more
doaj   +1 more source

Characterization of Single Nucleotide Variants of OPN3 Gene in Melanocytic Nevi and Melanoma

open access: yesJID Innovations, 2021
In this study, we examined single nucleotide variants (SNVs) of the OPN3 gene in malignant melanoma and melanocytic nevi. A total of 20 variants of SNVs were detected.
Wei Zhang   +5 more
doaj   +1 more source

Functional characterization of 5′ UTR cis-acting sequence elements that modulate translational efficiency in Plasmodium falciparum and humans

open access: yesMalaria Journal, 2022
Background The eukaryotic parasite Plasmodium falciparum causes millions of malarial infections annually while drug resistance to common anti-malarials is further confounding eradication efforts.
Valentina E. Garcia   +2 more
doaj   +1 more source

An mRNA-mRNA Interaction Couples Expression of a Virulence Factor and Its Chaperone in Listeria monocytogenes

open access: yesCell Reports, 2020
Summary: Bacterial pathogens often employ RNA regulatory elements located in the 5′ untranslated regions (UTRs) to control gene expression. Using a comparative structural analysis, we examine the structure of 5′ UTRs at a global scale in the pathogenic ...
Dmitriy Ignatov   +10 more
doaj   +1 more source

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