Structural diversity and biological role of the 5’ untranslated regions of picornavirus [PDF]
RNA Biology, 2023 The genomic arrangement of most picornavirus of the Picornaviridae family shares a similar monocistronic genomic pattern and a defining organizational feature.
Tingyu Peng +5 more
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Identification and Cross-Characterisation of Artificial Promoters and 5′ Untranslated Regions in Vibrio natriegens [PDF]
Frontiers in Bioengineering and Biotechnology, 2022 Vibrio natriegens has recently gained attention as a novel fast-growing bacterium in synthetic biology applications. Currently, a limited set of genetic elements optimised for Escherichia coli are used in V.
Lisa Tietze +3 more
doaj +4 more sources
Identification and Characterization of 5′ Untranslated Regions (5′UTRs) in Zymomonas mobilis as Regulatory Biological Parts [PDF]
Frontiers in Microbiology, 2017 Regulatory RNA regions within a transcript, particularly in the 5′ untranslated region (5′UTR), have been shown in a variety of organisms to control the expression levels of these mRNAs in response to various metabolites or environmental conditions ...
Seung Hee Cho +7 more
doaj +3 more sources
Differences in 5'untranslated regions highlight the importance of translational regulation of dosage sensitive genes [PDF]
Genome BiologyBackground Untranslated regions (UTRs) are important mediators of post-transcriptional regulation. The length of UTRs and the composition of regulatory elements within them are known to vary substantially across genes, but little is known about the ...
Nechama Wieder +12 more
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The 5′ and 3′ Untranslated Regions of the Flaviviral Genome
Viruses, 2017 Flaviviruses are enveloped arthropod-borne viruses with a single-stranded, positive-sense RNA genome that can cause serious illness in humans and animals.
Wy Ching Ng +4 more
doaj +4 more sources
Alternative 5' untranslated regions are involved in expression regulation of human heme oxygenase-1. [PDF]
PLoS ONE, 2013 The single nucleotide polymorphism rs2071746 and a (GT)n microsatellite within the human gene encoding heme oxygenase-1 (HMOX1) are associated with incidence or outcome in a variety of diseases.
Marcel Kramer +8 more
doaj +3 more sources
Evidence for widespread translation of 5′ untranslated regions [PDF]
Nucleic Acids ResearchNational Human Genome Research Institute of the National Institutes of Health [U41 HG007234]; Spanish Ministry of Science, Innovation and Universities [PGC2018- 097019-B-I00]; Carlos III Institute of Health-Fondo de Investigación Sanitaria [IPT17/0019]; ‘
JOSÉ Manuel Rodríguez +2 more
exaly +3 more sources
Genetic polymorphisms of the 5' untranslated regions of the HSP70 gene in Indonesian cattle populations [PDF]
Veterinary World, 2022 Background and Aim: Heat shock proteins (HSPs) are a group of proteins that play a significant role in protecting cells against cellular stress. HSP70 is a conserved, sensitive, and abundant gene associated with heat stress's physiological adaptability ...
Peni Wahyu Prihandini +4 more
doaj +2 more sources
The Roles of the 5′ and 3′ Untranslated Regions in Human Astrovirus Replication [PDF]
Viruses, 2023 Astroviruses are small nonenveloped single-stranded RNA viruses with a positive sense genome. They are known to cause gastrointestinal disease in a broad spectrum of species.
Nicole Wildi, Torsten Seuberlich
doaj +2 more sources
eIF3 and Its mRNA-Entry-Channel Arm Contribute to the Recruitment of mRNAs With Long 5′-Untranslated Regions [PDF]
Frontiers in Molecular Biosciences, 2022 Translation initiation in eukaryotes is a multi-step pathway and the most regulated phase of translation. Eukaryotic initiation factor 3 (eIF3) is the largest and most complex of the translation initiation factors, and it contributes to events throughout
Andrei Stanciu +6 more
doaj +2 more sources