Results 21 to 30 of about 345,197 (240)

Dengue and Zika Virus 5′ Untranslated Regions Harbor Internal Ribosomal Entry Site Functions [PDF]

mBio, 2019
The Flavivirus genus of the Flaviviridae family encompasses numerous enveloped plus-strand RNA viruses. Dengue virus (DENV), a flavivirus, is the leading cause of serious arthropod-borne disease globally.
Yutong Song, JoAnn Mugavero, Charles B. Stauft, Eckard Wimmer   +3 more
doaj   +2 more sources

Conserved Sequences in the 5′ and 3′ Untranslated Regions of Jingmenvirus Group Representatives

Viruses, 2023
The Jingmenvirus group (JVG), with members such as Jingmen tick virus (JMTV), Alongshan virus (ALSV), Yanggou tick virus (YGTV), and Takachi virus (TAKV), is drawing attention due to evidence of it causing disease in humans and its unique genome ...
Alexander G. Litov, Egor V. Okhezin, Ivan S. Kholodilov, Oxana A. Belova, Galina G. Karganova   +4 more
doaj   +2 more sources

The genomic features that affect the lengths of 5’ untranslated regions in multicellular eukaryotes [PDF]

BMC Bioinformatics, 2011
Background The lengths of 5’UTRs of multicellular eukaryotes have been suggested to be subject to stochastic changes, with upstream start codons (uAUGs) as the major constraint to suppress 5’UTR elongation.
Chen Feng-Chi, Pan Chia-Lin, Lin Hsuan-Yu, Chen Chun-Hsi   +3 more
doaj   +2 more sources

RNP interfaces as regulatory “active sites”: a repurposing strategy for small molecules targeting viral 5′-untranslated regions [PDF]

Frontiers in Molecular Biosciences
RNA-protein (RNP) complexes regulate nearly every stage of gene expression and play central roles in viral infection and human disease. Despite decades of research, relatively few small molecules (SMs) have been shown to modulate RNP assemblies with ...
Louis G. Smith, Solomon Attionu, Sudeshi M. Abedeera, Barrington Henry, Srinivasa Penumutchu, Srinivasa Penumutchu, Blanton S. Tolbert, Blanton S. Tolbert   +7 more
doaj   +2 more sources

Exploring the selective constraint on the sizes of insertions and deletions in 5' untranslated regions in mammals [PDF]

BMC Evolutionary Biology, 2011
Background Small insertions and deletions ("indels" with size ≦ 100 bp) whose lengths are not multiples of three (non-3n) are strongly constrained and depleted in protein-coding sequences.
Chen Feng-Chi, Liao Ben-Yang, Chen Chun-Hsi   +2 more
doaj   +2 more sources

Properties of untranslated regions of the S. cerevisiae genome

BMC Genomics, 2009
Background During evolution selection forces such as changing environments shape the architecture of genomes. The distribution of genes along chromosomes and the length of intragenic regions are basic genomic features known to play a major role in the ...
Tuller Tamir, Ruppin Eytan, Kupiec Martin   +2 more
doaj   +2 more sources

Regulatory feedback loop of two phz gene clusters through 5'-untranslated regions in Pseudomonas sp. M18. [PDF]

PLoS ONE, 2011
BACKGROUND: Phenazines are important compounds produced by pseudomonads and other bacteria. Two phz gene clusters called phzA1-G1 and phzA2-G2, respectively, were found in the genome of Pseudomonas sp.
Yaqian Li, Xilin Du, Zhi John Lu, Daqiang Wu, Yilei Zhao, Bin Ren, Jiaofang Huang, Xianqing Huang, Yuhong Xu, Yuquan Xu   +9 more
doaj   +2 more sources

Corrigendum: eIF3 and Its mRNA-Entry-Channel Arm Contribute to the Recruitment of mRNAs With Long 5′-Untranslated Regions [PDF]

Frontiers in Molecular Biosciences, 2022
Andrei Stanciu, Juncheng Luo, Lucy Funes, Shanya Galbokke Hewage, Shardul D. Kulkarni, Colin Echeverría Aitken, Colin Echeverría Aitken   +6 more
doaj   +2 more sources

A proposed new Tombusviridae genus featuring extremely long 5’ untranslated regions and a luteo/polerovirus-like gene block

Frontiers in Virology
Tombusviridae is a large family of single-stranded, positive-sense RNA plant viruses with uncapped, non-polyadenylated genomes encoding 4–7 open reading frames (ORFs).
Zachary Lozier, Zachary Lozier, Lilyahna Hill, Elizabeth Semmann, W. Allen Miller, W. Allen Miller   +5 more
doaj   +3 more sources

Posttranscriptional regulation ofcspEinEscherichia coli: involvement of the short 5′-untranslated region [PDF]

FEMS Microbiology Letters, 2008
Escherichia coli K-12 contains nine paralogs of CspA, namely CspA-CspI. In spite of considerable sequence similarity among these genes, the individual members of this family show significant differences in their expression regulation. Among these nine members, cspA, B, G and I have been reported to be cold-induced.
Sheetal, Uppal, Venkata S N Rao, Akkipeddi, Narendra, Jawali   +2 more
openaire   +2 more sources