Results 21 to 30 of about 42,924 (245)

Anatomic study of verumontanum during endoscopic surgeries in patients with benign prostatic hyperplasia [PDF]

International Brazilian Journal of Urology, 2021
Introduction and objective: To evaluate changes in verumontanum anatomy in patients with benign prostatic hyperplasia (BPH) who used 5-alpha reductase inhibitors (5-ARIs) and to propose an anatomical classification of the verumontanum.
Henrique Barbosa de Menezes, Francisco José Barcellos Sampaio, José Anacleto Dutra de Resende Júnior, Rodrigo Ribeiro Vieiralves, Fernando Salles da Silva Filho, Edilaine Alves, Luciano Alves Favorito   +6 more
doaj   +1 more source

Antipsychotic-Like Properties of 5-α-Reductase Inhibitors [PDF]

Neuropsychopharmacology, 2008
Recent evidence indicates that neuroactive steroids may participate in the pathogenesis of schizophrenia spectrum disorders, yet the mechanisms of this involvement are elusive. As 5-alpha-reductase (5AR) is the rate-limiting enzyme of one of the two major metabolic pathways in brain steroidogenesis, we investigated the effects of its blockade in ...
Bortolato M, FRAU, ROBERTO, Orrù M, Bourov, MARROSU, FRANCESCO, Mareu G, DEVOTO, PAOLA, Gessa GL   +7 more
openaire   +4 more sources

Preoperative treatment with 5α-reductase inhibitors and the risk of hemorrhagic events in patients undergoing transurethral resection of the prostate – A population-based cohort study

Clinics, 2018
OBJECTIVES: To assess the associations between preoperative treatment with 5-alpha reductase inhibitors and the risks of blood transfusion during transurethral resection of the prostate and blood clot evacuation or emergency department visits for ...
Ti-Yuan Yang, Marcelo Chen, Wun-Rong Lin, Chung-Yi Li, Wei-Kung Tsai, Allen W. Chiu, Ming-Chung Ko   +6 more
doaj   +1 more source

Effect of 5α-reductase inhibitors on the efficiency of thulium:yttrium-aluminium-garnet (RevoLix®) vaporesection for treating benign prostatic hyperplasia [PDF]

Investigative and Clinical Urology, 2020
Purpose: Preoperative use of 5α-reductase inhibitors (5ARIs) may cause fibrosis of the prostate tissue and reduce the efficiency of thulium laser surgery for treating benign prostate hyperplasia (BPH).
Jae Seung Chung, Won Ik Seo, Cheol Kyu Oh, Seong Cheol Kim, Myung Chan Park, Sang Hyun Park, Jihyeong Yu, Chan Ho Lee, Wansuk Kim, Tae Yong Park, Kweon Sik Min, Jae Il Chung   +11 more
doaj   +1 more source

Evaluation of Recent Trends in Treatment Patterns Among Men With Benign Prostatic Hyperplasia

American Journal of Men's Health, 2013
Although there is an abundance of evidence regarding clinical efficacy and safety of benign prostatic hyperplasia (BPH) treatment, real-world evidence is lacking for pharmacotherapy utilization and trends.
Eric J. Kruep PharmD, MS, Bridgett B. Goodwin PhD, Sham Chaudhari PharmD, MS   +2 more
doaj   +1 more source

Bothersome Hematospermia Following Stereotactic Body Radiation Therapy for Prostate Cancer

Frontiers in Oncology, 2021
BackgroundHematospermia following prostate radiation therapy is a benign and often self-limiting side effect. However, it may be bothersome to some men and their partners with a negative impact on sexual quality of life (QOL).
Sarthak Shah, Tamir Sholklapper, Michael Creswell, Abigail Pepin, Jonathan Cantalino, Ryan Andrew Hankins, Simeng Suy, Sean P. Collins   +7 more
doaj   +1 more source

Effect of 5-alpha Reductase Inhibitor on Storage Symptoms in Patients with Benign Prostatic Hyperplasia [PDF]

International Neurourology Journal, 2011
Purpose Many patients with benign prostatic hyperplasia (BPH) have storage symptoms. The aim of this study was to evaluate the effects of treatment with a 5-alpha reductase inhibitor (5ARI) on storage symptoms in patients with BPH. Methods This study was
Kang Jun Cho, Se Hee Kang, Hyo Sin Kim, Jun Sung Koh, Joon Chul Kim   +4 more
doaj   +1 more source

Inhibition of sterol biosynthesis in animal cells by 14 alpha-hydroxymethyl sterols.

Journal of Lipid Research, 1980
The chemical syntheses of a number of 14 alpha-hydroxymethyl sterols and 14 alpha -hydroxymethyl-15 alpha-hydroxysterols and their derivatives have been pursued to permit evaluation of their activity in the inhibition of sterol biosynthesis in animal ...
G J Schroepfer, Jr, E J Parish, R A Pascal, Jr, A A Kandutsch   +3 more
doaj   +1 more source

Estudio de la expresión de receptores de andrógenos, estrógenos y progesterona mediante inmunohistoquímica en pacientes con alopecia frontal fibrosante

Revista Médica Clínica Las Condes, 2023
Resumen: Introducción: La alopecia frontal fibrosante (AFF) es una alopecia linfocítica primaria cicatricial, cuya patogenia se desconoce. Se han desarrollado distintos regímenes de tratamientos farmacológicos, siendo el finasteride por sí sólo o en ...
Néstor Carreño-Orellana, Daniela Alfaro-Sepúlveda, María Paz Traipe, Verónica Vial-Letelier   +3 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source